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> Protein (NX_P28329)
Protein (NX_P28329)
Protein
Gene SymbolCHAT to neXtProt (NX_P28329)
DescriptionCholine O-acetyltransferase
Chromosome10
Location10q11.23 (50817141 ~ 50901925) to Ensembl
Sequene Features : Isoforms 3, Variants 159, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.glycerophospholipid biosynthetic process
.small molecule metabolic process
.rhythmic excitation
  + 11 more...
.choline O-acetyltransferase activity .neuronal cell body
.axon
.cytosol
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 159 0
2014-09-19protein level
3 129 0
2014-05-27protein level
3 129 0
2014-02-25protein level
3 128 0
2013-12-09protein level
3 101 0
2013-11-01protein level
3 95 0
2013-09-12protein level
3 95 0
2013-08-17protein level
3 95 0
2013-07-15protein level
3 76 0
2013-06-11protein level
3 76 0
2013-02-12protein level
3 44 0
2012-12-20protein level
3 48 0
2012-10-30protein level
3 56 0
2012-10-07protein level
3 56 0
2012-08-24protein level
3 55 0
2012-07-28protein level
3 54 0
2012-06-08protein level
3 62 0
2012-05-07protein level
3 56 0
2012-04-10protein level
3 56 0
2012-01-13protein level
3 51 0
2011-12-20protein level
3 51 0
2011-11-11protein level
3 51 0
2011-08-23protein level
3 51 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P28329-1
4 33 0 82482.7933
NX_P28329-2
1 33 0 74312.6227
NX_P28329-3
0 33 0 70348.5452
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain4
eye4
testis2
Health State
TissuesTPM*
primitive neuroectodermal tumor of the CNS7
retinoblastoma21
Developmental Stage
TissuesTPM*
adult1
infant42
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
placenta4.3
Tissues
TissuesExpression level
colonMedium
duodenumMedium
rectumMedium
small intestineMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*118490, gene) Choline acetyltransferase; CHATOMIM
2(#254210, phenotype) Myasthenic syndrome, congenital, associated with episodic apneaOMIM


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