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> Protein (NX_P29083)
Protein (NX_P29083)
Protein
Gene SymbolGTF2E1 to neXtProt (NX_P29083)
DescriptionGeneral transcription factor IIE subunit 1
Chromosome3
Location3q13.33 (120461484 ~ 120501916) to Ensembl
Sequene Features : Isoforms 1, Variants 75, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.viral process
.gene expression
.transcription elongation from RNA polymerase II promoter
  + 3 more...
.metal ion binding
.sequence-specific DNA binding
.intermediate filament cytoskeleton
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 75 3
2014-09-19protein level
1 62 3
2014-05-27protein level
1 62 3
2014-02-25protein level
1 62 3
2013-12-09protein level
1 47 3
2013-11-01protein level
1 44 3
2013-09-12protein level
1 44 3
2013-08-17protein level
1 44 3
2013-07-15protein level
1 33 3
2013-06-11protein level
1 33 3
2013-02-12protein level
1 15 3
2012-12-20protein level
1 15 3
2012-10-30protein level
1 21 3
2012-10-07protein level
1 21 3
2012-08-24protein level
1 21 3
2012-07-28protein level
1 21 3
2012-06-08protein level
1 23 3
2012-05-07protein level
1 17 3
2012-04-10protein level
1 17 3
2012-01-13protein level
1 6 3
2011-12-20protein level
1 6 3
2011-11-11protein level
1 6 3
2011-08-23protein level
1 6 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P29083-1
17 0 0 49420.8782
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5462215,EBI-2853321 GTF2E2  
  .viral process
.gene expression
.transcription elongation from RNA polymerase II promoter
  + 3 more...
.poly(A) RNA binding
.DNA binding
.cytoplasm
.transcription factor TFIIE complex
.nucleoplasm
.nucleus
2 EBI-5462215,EBI-715539 GTF2H1  
  .positive regulation of viral transcription
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of gene expression, epigenetic
  + 17 more...
.N/A .holo TFIIH complex
.nucleoplasm
.core TFIIH complex
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
blood16
brain10
eye9
heart11
intestine8
kidney14
liver19
lung2
lymph node11
mammary gland6
mouth60
muscle9
placenta7
skin18
spleen18
stomach10
testis39
thymus100
thyroid21
vascular19
Health State
TissuesTPM*
normal12
breast (mammary gland) tumor10
germ cell tumor22
head and neck tumor37
kidney tumor14
leukemia10
liver tumor20
lung tumor9
non-neoplasia10
skin tumor31
Developmental Stage
TissuesTPM*
adult8
fetus23
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.2
adrenal gland7
appendix8
bone marrow2.5
cerebral cortex4.7
colon6.3
duodenum4.5
esophagus5
gallbladder4.2
heart muscle4.3
kidney5.5
liver2.6
lung4.4
lymph node8.9
ovary5.3
pancreas2.5
placenta6.1
prostate5.2
salivary gland3.9
skin2.8
small intestine4.6
spleen9
stomach4.7
testis10.6
thyroid gland5.8
urinary bladder7.3
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowHigh
breastMedium
bronchusHigh
cerebellumHigh
cerebral cortexMedium
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1High
endometrium 2High
epididymisHigh
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleLow
hippocampusHigh
kidneyHigh
lateral ventricleMedium
liverLow
lungHigh
lymph nodeHigh
nasopharynxHigh
oral mucosaHigh
ovaryHigh
pancreasHigh
parathyroid glandHigh
placentaHigh
prostateMedium
rectumHigh
salivary glandHigh
seminal vesicleMedium
skeletal muscleLow
skin 1High
skin 2High
small intestineHigh
smooth muscleMedium
soft tissue 1Medium
spleenHigh
stomach 1High
stomach 2High
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*189962, gene) General transcription factor iie, polypeptide 1; GTF2E1OMIM


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