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> Protein (NX_P29218)
Protein (NX_P29218)
Protein
Gene SymbolIMPA1 to neXtProt (NX_P29218)
DescriptionInositol monophosphatase 1
Chromosome8
Location8q21.13 (82570196 ~ 82598928) to Ensembl
Sequene Features : Isoforms 3, Variants 49, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.inositol phosphate dephosphorylation
.phosphatidylinositol phosphorylation
.small molecule metabolic process
  + 5 more...
.inositol monophosphate phosphatase activity
.inositol monophosphate 4-phosphatase activity
.inositol monophosphate 3-phosphatase activity
  + 6 more...
.extracellular exosome
.cytosol
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 49 2
2014-09-19protein level
3 37 2
2014-05-27protein level
3 36 2
2014-02-25protein level
3 36 2
2013-12-09protein level
3 27 2
2013-11-01protein level
3 27 2
2013-09-12protein level
3 27 2
2013-08-17protein level
3 27 2
2013-07-15protein level
3 18 1
2013-06-11protein level
3 18 1
2013-02-12protein level
2 11 0
2012-12-20protein level
2 12 0
2012-10-30protein level
2 12 0
2012-10-07protein level
2 12 0
2012-08-24protein level
2 6 0
2012-07-28protein level
2 6 0
2012-06-08protein level
2 8 0
2012-05-07protein level
2 8 0
2012-04-10protein level
2 8 0
2012-01-13protein level
1 9 0
2011-12-20protein level
1 9 0
2011-11-11protein level
1 9 0
2011-08-23protein level
1 9 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P29218-1
0 15 0 30169.0813
NX_P29218-2
2 9 0 21941.0151
NX_P29218-3
2 15 0 36670.6699
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-752410,EBI-725233 IMPA2  
  .inositol phosphate dephosphorylation
.phosphatidylinositol phosphorylation
.small molecule metabolic process
  + 4 more...
.inositol monophosphate 4-phosphatase activity
.inositol monophosphate 3-phosphatase activity
.metal ion binding
  + 2 more...
.cytosol
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites50
bladder200
blood65
bone13
bone marrow225
brain86
cervix82
connective tissue107
embryonic tissue14
eye33
heart22
intestine38
kidney75
larynx85
liver43
lung23
lymph22
lymph node44
mammary gland19
mouth30
muscle9
ovary29
pancreas51
pharynx24
placenta38
prostate68
salivary gland98
skin37
spleen18
stomach20
testis94
thymus75
thyroid21
trachea19
uterus43
vascular77
Health State
TissuesTPM*
normal48
adrenal tumor79
bladder carcinoma341
breast (mammary gland) tumor21
cervical tumor28
chondrosarcoma12
colorectal tumor17
gastrointestinal tumor25
germ cell tumor34
glioma9
head and neck tumor37
kidney tumor58
leukemia95
liver tumor52
lung tumor19
lymphoma41
non-neoplasia62
ovarian tumor39
pancreatic tumor9
primitive neuroectodermal tumor of the CNS94
prostate cancer96
retinoblastoma129
skin tumor39
soft tissue/muscle tissue tumor95
uterine tumor44
Developmental Stage
TissuesTPM*
adult36
embryoid body14
neonate128
fetus41
infant42
juvenile179
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12.7
adrenal gland15.1
appendix16.7
bone marrow18.4
cerebral cortex24.4
colon29.2
duodenum29.1
esophagus21.9
gallbladder17
heart muscle22.4
kidney18
liver19.5
lung12.4
lymph node21.3
ovary15.9
pancreas4.5
placenta8.6
prostate13.8
salivary gland8.2
skin5.9
small intestine27.3
spleen12.5
stomach16.5
testis42.7
thyroid gland27.4
urinary bladder18
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602064, gene) Myo-inositol monophosphatase 1; IMPA1OMIM


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