Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_P29728)
Protein (NX_P29728)
Protein
Gene SymbolOAS2 to neXtProt (NX_P29728)
Description2'-5'-oligoadenylate synthase 2
Chromosome12
Location12q24.13 (113416200 ~ 113449528) to Ensembl
Sequene Features : Isoforms 3, Variants 115, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.type I interferon signaling pathway
.interferon-gamma-mediated signaling pathway
.defense response to virus
  + 7 more...
.metal ion binding
.zinc ion binding
.ATP binding
  + 2 more...
.perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.membrane
  + 5 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 115 3
2014-09-19protein level
3 93 3
2014-05-27protein level
3 93 4
2014-02-25protein level
3 93 4
2013-12-09protein level
3 69 4
2013-11-01protein level
3 64 4
2013-09-12protein level
3 64 4
2013-08-17protein level
3 64 4
2013-07-15protein level
3 35 4
2013-06-11protein level
3 35 4
2013-02-12protein level
3 22 7
2012-12-20protein level
3 23 7
2012-10-30protein level
3 28 7
2012-10-07protein level
3 28 3
2012-08-24protein level
3 25 3
2012-07-28protein level
3 25 3
2012-06-08protein level
3 38 3
2012-05-07protein level
3 31 3
2012-04-10protein level
2 29 3
2012-01-13protein level
2 18 3
2011-12-20protein level
2 18 3
2011-11-11protein level
2 18 3
2011-08-23protein level
2 18 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P29728-1
2 26 0 82378.2742
NX_P29728-2
0 26 0 78736.5948
NX_P29728-3
3 4 0 19504.7968
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10211452,EBI-745579 CLK3  
  .protein autophosphorylation
.regulation of RNA splicing
.protein phosphorylation
.poly(A) RNA binding
.ATP binding
.protein tyrosine kinase activity
  + 2 more...
.intermediate filament cytoskeleton
.nuclear speck
.membrane
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder133
blood130
bone27
bone marrow20
brain13
cervix41
connective tissue40
ear62
heart11
intestine64
kidney23
liver29
lung35
lymph158
lymph node178
mammary gland119
mouth60
muscle9
ovary29
pancreas4
pharynx24
placenta56
prostate10
skin18
spleen149
stomach62
testis11
thymus50
trachea231
uterus112
vascular19
Health State
TissuesTPM*
normal29
breast (mammary gland) tumor128
cervical tumor57
chondrosarcoma60
colorectal tumor97
gastrointestinal tumor33
germ cell tumor53
glioma27
head and neck tumor29
kidney tumor29
leukemia42
liver tumor41
lung tumor38
lymphoma110
non-neoplasia31
ovarian tumor39
pancreatic tumor9
skin tumor23
soft tissue/muscle tissue tumor175
uterine tumor66
Developmental Stage
TissuesTPM*
adult54
neonate32
fetus23
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue12.6
adrenal gland6.3
appendix33.5
bone marrow11.5
cerebral cortex5
colon10.2
duodenum11.1
esophagus16.1
gallbladder23.3
heart muscle8.3
kidney4.8
liver7.8
lung29.4
lymph node45.7
ovary2.2
placenta23.6
prostate6.2
salivary gland52.6
skin2.5
small intestine8.4
spleen49
stomach23.7
testis6.3
thyroid gland6.4
urinary bladder33.8
Tissues
TissuesExpression level
adrenal glandMedium
appendixHigh
bone marrowHigh
breastMedium
bronchusMedium
cerebellumHigh
cerebral cortexHigh
cervix, uterineHigh
colonHigh
duodenumHigh
endometrium 1High
endometrium 2Medium
epididymisHigh
esophagusHigh
fallopian tubeHigh
gallbladderHigh
heart muscleHigh
hippocampusHigh
kidneyHigh
lateral ventricleHigh
liverHigh
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaHigh
ovaryMedium
pancreasMedium
parathyroid glandMedium
placentaHigh
prostateHigh
rectumMedium
salivary glandMedium
seminal vesicleHigh
skeletal muscleMedium
skin 1High
skin 2Medium
small intestineHigh
smooth muscleMedium
soft tissue 1High
soft tissue 2High
spleenHigh
stomach 1High
stomach 2Medium
testisHigh
thyroid glandMedium
tonsilHigh
urinary bladderHigh
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603350, gene) 2-prime,5-prime-@oligoadenylate synthetase 2; OAS2OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center