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> Protein (NX_P30520)
Protein (NX_P30520)
Protein
Gene SymbolADSS to neXtProt (NX_P30520)
DescriptionAdenylosuccinate synthetase isozyme 2
Chromosome1
Location1q44 (244571796 ~ 244615436) to Ensembl
Sequene Features : Isoforms 1, Variants 43, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to electrical stimulus
.response to ammonium ion
.nucleobase-containing small molecule metabolic process
  + 9 more...
.phosphate ion binding
.GTP binding
.adenylosuccinate synthase activity
.magnesium ion binding
.extracellular exosome
.plasma membrane
.cytosol
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 43 4
2014-09-19protein level
1 35 4
2014-05-27protein level
1 35 4
2014-02-25protein level
1 35 4
2013-12-09protein level
1 28 4
2013-11-01protein level
1 27 2
2013-09-12protein level
1 27 2
2013-08-17protein level
1 27 2
2013-07-15protein level
1 14 0
2013-06-11protein level
1 14 0
2013-02-12protein level
1 5 1
2012-12-20protein level
1 5 1
2012-10-30protein level
1 8 1
2012-10-07protein level
1 8 1
2012-08-24protein level
1 5 1
2012-07-28protein level
1 5 1
2012-06-08protein level
1 6 1
2012-05-07protein level
1 6 1
2012-04-10protein level
1 6 1
2012-01-13protein level
1 5 1
2011-12-20protein level
1 5 1
2011-11-11protein level
1 5 1
2011-08-23protein level
1 5 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P30520-1
18 0 1 50065.6314
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1042898,EBI-8463848 SMYD1  
  .negative regulation of transcription, DNA-templated
.positive regulation of myoblast differentiation
.skeletal muscle cell differentiation
  + 4 more...
.metal ion binding
.histone-lysine N-methyltransferase activity
.transcription corepressor activity
.DNA binding
.cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites25
bladder200
blood155
bone41
bone marrow143
brain76
cervix41
connective tissue40
ear124
embryonic tissue70
esophagus198
eye95
heart67
intestine34
kidney75
liver48
lung68
lymph22
lymph node122
mammary gland66
mouth60
muscle28
ovary68
pancreas46
parathyroid194
pituitary gland121
placenta35
prostate89
skin90
spleen168
stomach41
testis167
thymus75
thyroid107
trachea251
umbilical cord145
uterus124
vascular348
Health State
TissuesTPM*
normal85
adrenal tumor79
bladder carcinoma227
breast (mammary gland) tumor85
cervical tumor57
chondrosarcoma24
colorectal tumor26
esophageal tumor231
gastrointestinal tumor25
germ cell tumor170
glioma46
head and neck tumor67
kidney tumor87
leukemia127
liver tumor93
lymphoma41
non-neoplasia62
ovarian tumor91
pancreatic tumor47
primitive neuroectodermal tumor of the CNS94
prostate cancer48
retinoblastoma129
skin tumor31
soft tissue/muscle tissue tumor63
uterine tumor110
Developmental Stage
TissuesTPM*
adult75
embryoid body85
blastocyst32
neonate386
fetus66
infant170
juvenile143
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue14.3
adrenal gland18.6
appendix26.3
bone marrow22.6
cerebral cortex23
colon24.9
duodenum22.3
esophagus26.1
gallbladder19.3
heart muscle5.6
kidney23.8
liver11.5
lung21
lymph node26.8
ovary18
pancreas8
placenta20.4
prostate19.3
salivary gland13.1
skin24.8
small intestine22.1
spleen19.9
stomach25.8
testis51.4
thyroid gland29
urinary bladder28.6
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderMedium
hippocampusLow
kidneyMedium
liverMedium
lungLow
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryLow
pancreasMedium
placentaHigh
prostateMedium
rectumMedium
seminal vesicleMedium
skeletal muscleLow
skin 1Low
skin 2Medium
small intestineMedium
smooth muscleMedium
soft tissue 2Low
spleenMedium
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*103060, gene) Adenylosuccinate synthetase; ADSSOMIM


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