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> Protein (NX_P31146)
Protein (NX_P31146)
Protein
Gene SymbolCORO1A to neXtProt (NX_P31146)
DescriptionCoronin-1A
Chromosome16
Location16p11.2 (30194148 ~ 30200397) to Ensembl
Sequene Features : Isoforms 1, Variants 51, PTMs 11 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to interleukin-4
.early endosome to recycling endosome transport
.regulation of release of sequestered calcium ion into cytosol
  + 23 more...
.actin filament binding
.poly(A) RNA binding
.phosphatidylinositol 3-kinase binding
  + 6 more...
.extracellular exosome
.phagocytic vesicle
.protein complex
  + 12 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 51 11
2014-09-19protein level
1 37 11
2014-05-27protein level
1 37 12
2014-02-25protein level
1 36 12
2013-12-09protein level
1 29 12
2013-11-01protein level
1 24 12
2013-09-12protein level
1 24 12
2013-08-17protein level
1 24 12
2013-07-15protein level
1 17 4
2013-06-11protein level
1 17 4
2013-02-12protein level
1 9 3
2012-12-20protein level
1 9 3
2012-10-30protein level
1 7 3
2012-10-07protein level
1 7 3
2012-08-24protein level
1 7 3
2012-07-28protein level
1 7 3
2012-06-08protein level
1 9 3
2012-05-07protein level
1 7 3
2012-04-10protein level
1 7 3
2012-01-13protein level
1 8 3
2011-12-20protein level
1 8 3
2011-11-11protein level
1 8 3
2011-08-23protein level
1 8 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P31146-1
20 0 0 50993.6551
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1046676,EBI-5661036 FSD2  
  .N/A .N/A .N/A
2 EBI-1046676,EBI-518675 STAT3  
  .negative regulation of neuron migration
.interleukin-6-mediated signaling pathway
.JAK-STAT cascade involved in growth hormone signaling pathway
  + 35 more...
.protein dimerization activity
.transcription regulatory region DNA binding
.protein phosphatase binding
  + 9 more...
.plasma membrane
.cytosol
.mitochondrial inner membrane
  + 4 more...
3 EBI-1046676,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland60
blood1079
bone55
bone marrow143
brain133
cervix20
connective tissue167
embryonic tissue9
esophagus99
eye47
heart67
intestine185
kidney23
liver29
lung83
lymph1715
lymph node490
mammary gland59
mouth30
muscle28
nerve64
ovary39
pancreas163
pharynx122
placenta109
prostate26
skin14
spleen1591
stomach125
testis11
thymus3500
tonsil5522
trachea57
uterus133
vascular96
Health State
TissuesTPM*
normal180
breast (mammary gland) tumor64
chondrosarcoma36
colorectal tumor26
esophageal tumor57
gastrointestinal tumor50
germ cell tumor125
glioma93
head and neck tumor37
kidney tumor29
leukemia709
liver tumor20
lung tumor136
lymphoma1509
non-neoplasia445
ovarian tumor26
pancreatic tumor304
primitive neuroectodermal tumor of the CNS110
prostate cancer38
retinoblastoma86
skin tumor23
soft tissue/muscle tissue tumor15
uterine tumor77
Developmental Stage
TissuesTPM*
adult114
blastocyst32
neonate579
fetus113
infant127
juvenile809
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue27.5
adrenal gland17.6
appendix247
bone marrow337.9
cerebral cortex28.9
colon24.6
duodenum40.3
esophagus19.6
gallbladder45.5
heart muscle8.7
kidney7.4
liver11.1
lung48.4
lymph node434
ovary7.4
pancreas4
placenta15.9
prostate12.1
salivary gland24
skin14.7
small intestine51.7
spleen234.5
stomach53
testis7.5
thyroid gland8.6
urinary bladder80.4
Tissues
TissuesExpression level
appendixHigh
bone marrowHigh
cerebral cortexMedium
endometrium 2Medium
hippocampusMedium
lateral ventricleHigh
lymph nodeHigh
skin 1High
spleenHigh
tonsilHigh
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605000, gene) Coronin 1a; CORO1AOMIM


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