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> Protein (NX_P31944)
Protein (NX_P31944)
Protein
Gene SymbolCASP14 to neXtProt (NX_P31944)
DescriptionCaspase-14
Chromosome19
Location19p13.12 (15160195 ~ 15169104) to Ensembl
Sequene Features : Isoforms 1, Variants 52, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.extrinsic apoptotic signaling pathway in absence of ligand
.cornification
.keratinization
  + 3 more...
.cysteine-type endopeptidase activity involved in apoptotic signaling pathway
.cysteine-type endopeptidase activity
.extracellular exosome
.keratin filament
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 52 0
2014-09-19protein level
1 42 0
2014-05-27protein level
1 42 0
2014-02-25protein level
1 41 0
2013-12-09protein level
1 35 0
2013-11-01protein level
1 31 0
2013-09-12protein level
1 31 0
2013-08-17protein level
1 31 0
2013-07-15protein level
1 26 0
2013-06-11protein level
1 26 0
2013-02-12protein level
1 20 0
2012-12-20protein level
1 18 0
2012-10-30protein level
1 21 0
2012-10-07protein level
1 21 0
2012-08-24protein level
1 18 0
2012-07-28protein level
1 18 0
2012-06-08protein level
1 20 0
2012-05-07protein level
1 12 0
2012-04-10protein level
1 12 0
2012-01-13protein level
1 2 0
2011-12-20protein level
1 2 0
2011-11-11protein level
1 2 0
2011-08-23protein level
1 2 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P31944-1
14 0 0 27661.8726
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2510738,EBI-716699 PSAP  
  .cellular response to organic substance
.epithelial cell differentiation involved in prostate gland development
.prostate gland growth
  + 10 more...
.lipid binding
.enzyme activator activity
.extracellular exosome
.intracellular membrane-bounded organelle
.lysosomal lumen
  + 8 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder100
esophagus49
lymph node33
mammary gland6
skin279
thymus12
thyroid21
uterus236
Health State
TissuesTPM*
normal17
bladder carcinoma170
esophageal tumor57
gastrointestinal tumor25
head and neck tumor7
skin tumor15
uterine tumor344
Developmental Stage
TissuesTPM*
adult31
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
skin367.6
Tissues
TissuesExpression level
skin 1Medium
skin 2Medium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*605848, gene) Caspase 14, apoptosis-related cysteine protease; CASP14OMIM


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