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> Protein (NX_P32321)
Protein (NX_P32321)
Protein
Gene SymbolDCTD to neXtProt (NX_P32321)
DescriptionDeoxycytidylate deaminase
Chromosome4
Location4q35.1 (183811213 ~ 183839089) to Ensembl
Sequene Features : Isoforms 2, Variants 27, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.nucleobase-containing small molecule metabolic process
.pyrimidine nucleoside biosynthetic process
.small molecule metabolic process
  + 3 more...
.zinc ion binding
.dCMP deaminase activity
.extracellular exosome
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 27 0
2014-09-19protein level
2 25 0
2014-05-27protein level
2 25 0
2014-02-25protein level
2 25 0
2013-12-09protein level
2 22 0
2013-11-01protein level
2 22 0
2013-09-12protein level
2 22 0
2013-08-17protein level
2 22 0
2013-07-15protein level
2 15 0
2013-06-11protein level
2 15 0
2013-02-12protein level
2 3 2
2012-12-20protein level
2 3 2
2012-10-30protein level
2 4 2
2012-10-07protein level
2 4 1
2012-08-24protein level
2 2 1
2012-07-28protein level
2 2 1
2012-06-08protein level
2 4 1
2012-05-07protein level
2 4 1
2012-04-10protein level
2 4 1
2012-01-13protein level
2 7 1
2011-12-20protein level
2 7 1
2011-11-11protein level
2 7 1
2011-08-23protein level
2 7 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P32321-1
0 10 0 20002.7284
NX_P32321-2
1 10 0 21000.1367
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-739870,EBI-727004 SDCBP  
  .positive regulation of extracellular exosome assembly
.positive regulation of exosomal secretion
.ephrin receptor signaling pathway
  + 9 more...
.protein N-terminus binding
.protein heterodimerization activity
.syndecan binding
  + 4 more...
.blood microparticle
.extracellular exosome
.melanosome
  + 12 more...
2 EBI-739870,EBI-6657662 FGF12  
  .negative regulation of cation channel activity
.regulation of sodium ion transmembrane transporter activity
.regulation of sodium ion transmembrane transport
  + 12 more...
.ion channel binding
.sodium channel regulator activity
.heparin binding
.growth factor activity
.nucleus
.extracellular space
3 EBI-739870,EBI-2339737 MALSU1  
  .negative regulation of ribosome biogenesis
.negative regulation of mitochondrial translation
.ribosomal large subunit biogenesis
.ribosomal large subunit binding .mitochondrial matrix
.mitochondrion
.cytoplasm
4 EBI-739870,EBI-2932492 TXN2  
  .oxidation-reduction process
.response to axon injury
.cell redox homeostasis
  + 12 more...
.peptide-methionine (R)-S-oxide reductase activity
.oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
.protein disulfide oxidoreductase activity
.peptide-methionine (S)-S-oxide reductase activity
.neuronal cell body
.dendrite
.mitochondrial matrix
  + 2 more...
5 EBI-739870,EBI-739467 GORASP2  
  .organelle organization
.mitotic cell cycle
.N/A .membrane
.Golgi apparatus
.Golgi membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland212
ascites100
blood73
bone223
brain66
cervix226
connective tissue114
ear62
embryonic tissue89
esophagus297
eye114
heart122
intestine90
kidney90
liver68
lung65
lymph45
lymph node44
mammary gland138
mouth15
muscle18
nerve64
ovary88
pancreas112
parathyroid97
pharynx98
pituitary gland60
placenta35
prostate163
salivary gland49
skin75
spleen74
stomach125
testis55
thymus25
thyroid107
umbilical cord145
uterus116
vascular58
Health State
TissuesTPM*
normal79
adrenal tumor79
breast (mammary gland) tumor161
cervical tumor231
chondrosarcoma144
colorectal tumor106
esophageal tumor347
gastrointestinal tumor143
germ cell tumor41
glioma167
head and neck tumor37
kidney tumor87
leukemia74
liver tumor114
lung tumor68
lymphoma27
non-neoplasia165
ovarian tumor91
pancreatic tumor161
primitive neuroectodermal tumor of the CNS110
prostate cancer144
retinoblastoma86
skin tumor71
soft tissue/muscle tissue tumor39
uterine tumor166
Developmental Stage
TissuesTPM*
adult97
embryoid body85
blastocyst65
neonate96
fetus89
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue42.5
adrenal gland58.8
appendix44
bone marrow19.2
cerebral cortex25.1
colon39.6
duodenum28.7
esophagus52.5
gallbladder60.7
heart muscle34.1
kidney46.5
liver46.5
lung39.1
lymph node45.8
ovary64.7
pancreas26.5
placenta32.8
prostate39.7
salivary gland34.1
skin30.2
small intestine27.7
spleen50
stomach49.2
testis25.9
thyroid gland102.7
urinary bladder57.1
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowLow
bronchusMedium
cerebellumHigh
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumHigh
endometrium 1Medium
epididymisHigh
esophagusMedium
fallopian tubeMedium
gallbladderHigh
heart muscleMedium
hippocampusLow
kidneyHigh
lateral ventricleLow
liverMedium
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryMedium
pancreasMedium
parathyroid glandMedium
placentaHigh
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleLow
skin 1High
skin 2High
small intestineHigh
smooth muscleMedium
soft tissue 1Low
soft tissue 2High
spleenMedium
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandHigh
tonsilMedium
urinary bladderMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607638, gene) Deoxycytidylate deaminase; DCTDOMIM


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