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> Protein (NX_P38405)
Protein (NX_P38405)
Protein
Gene SymbolGNAL to neXtProt (NX_P38405)
DescriptionGuanine nucleotide-binding protein G(olf) subunit alpha
Chromosome18
Location18p11.21 (11688955 ~ 11885684) to Ensembl
Sequene Features : Isoforms 3, Variants 40, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.response to caffeine
.metabolic process
.sensory perception of smell
  + 7 more...
.metal ion binding
.G-protein beta/gamma-subunit complex binding
.GTP binding
  + 3 more...
.extracellular exosome
.plasma membrane
.heterotrimeric G-protein complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 40 5
2014-09-19protein level
3 29 5
2014-05-27protein level
3 29 8
2014-02-25protein level
3 29 8
2013-12-09protein level
3 25 8
2013-11-01protein level
3 23 8
2013-09-12protein level
3 23 8
2013-08-17protein level
3 23 8
2013-07-15protein level
3 11 6
2013-06-11protein level
3 11 6
2013-02-12protein level
3 5 6
2012-12-20protein level
2 4 6
2012-10-30protein level
2 6 6
2012-10-07protein level
2 6 4
2012-08-24protein level
2 6 4
2012-07-28protein level
2 6 4
2012-06-08protein level
2 7 4
2012-05-07protein level
2 3 4
2012-04-10protein level
2 3 4
2012-01-13protein level
1 1 4
2011-12-20protein level
1 1 4
2011-11-11protein level
1 1 4
2011-08-23protein level
1 1 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P38405-1
2 12 3 44280.32
NX_P38405-2
3 12 3 52421.5308
NX_P38405-3
0 5 2 20509.1625
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
brain85
connective tissue6
ear62
embryonic tissue14
eye19
heart11
intestine4
liver9
lung23
mouth15
pancreas18
pituitary gland60
placenta21
prostate10
skin28
testis25
thymus25
trachea19
uterus12
vascular19
Health State
TissuesTPM*
normal42
bladder carcinoma56
germ cell tumor11
glioma18
head and neck tumor7
non-neoplasia10
pancreatic tumor38
uterine tumor22
Developmental Stage
TissuesTPM*
adult17
blastocyst16
fetus96
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue8.2
adrenal gland1.6
appendix3.5
cerebral cortex19.2
colon3.9
duodenum1.6
esophagus15.8
gallbladder9.5
heart muscle1.6
kidney3.9
lung2.4
lymph node7
ovary3.6
placenta2.9
prostate10.1
salivary gland4.6
skin10
small intestine2.7
spleen1.9
stomach1.6
testis9
thyroid gland12.7
urinary bladder13.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*139312, gene) Guanine nucleotide-binding protein, alpha-activating activity polypeptide,OMIM


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