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> Protein (NX_P40933)
Protein (NX_P40933)
Protein
Gene SymbolIL15 to neXtProt (NX_P40933)
DescriptionInterleukin-15
Chromosome4
Location4q31.21 (142557752 ~ 142655140) to Ensembl
Sequene Features : Isoforms 2, Variants 26, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to vitamin D
.positive regulation of immune response
.positive regulation of inflammatory response
  + 23 more...
.cytokine activity .membrane
.cell surface
.integral component of plasma membrane
  + 6 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 26 3
2014-09-19protein level
2 20 3
2014-05-27protein level
2 20 3
2014-02-25protein level
2 20 3
2013-12-09protein level
2 17 3
2013-11-01protein level
2 16 3
2013-09-12protein level
2 16 3
2013-08-17protein level
2 16 3
2013-07-15protein level
2 9 3
2013-06-11protein level
2 9 3
2013-02-12protein level
2 5 6
2012-12-20protein level
2 6 6
2012-10-30protein level
2 7 6
2012-10-07protein level
2 7 3
2012-08-24protein level
2 7 3
2012-07-28protein level
2 7 3
2012-06-08protein level
2 8 3
2012-05-07protein level
2 7 3
2012-04-10protein level
2 7 3
2012-01-13protein level
2 5 3
2011-12-20protein level
2 5 3
2011-11-11protein level
2 5 3
2011-08-23protein level
2 5 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P40933-1
1 5 0 18074.0357
NX_P40933-2
1 5 0 14902.2807
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-980274,EBI-2866779 IL2RB  
  .negative regulation of apoptotic process
.interleukin-2-mediated signaling pathway
.cytokine-mediated signaling pathway
  + 3 more...
.interleukin-2 binding
.interleukin-2 receptor activity
.membrane
.external side of plasma membrane
.integral component of plasma membrane
.plasma membrane
2 EBI-980274,EBI-980354 IL15RA  
  .cytokine-mediated signaling pathway
.cell proliferation
.signal transduction
.cytokine receptor activity
.signal transducer activity
.nuclear membrane
.cytoplasmic vesicle membrane
.integral component of membrane
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
brain4
connective tissue20
embryonic tissue4
eye9
kidney4
larynx85
lung2
muscle9
placenta24
stomach10
thymus12
thyroid21
uterus25
vascular58
Health State
TissuesTPM*
normal8
chondrosarcoma24
germ cell tumor3
head and neck tumor22
lung tumor9
non-neoplasia41
soft tissue/muscle tissue tumor7
uterine tumor44
Developmental Stage
TissuesTPM*
adult16
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.4
adrenal gland3
appendix8.4
bone marrow2.5
colon5.7
duodenum6.8
esophagus5.7
gallbladder9.1
heart muscle8.4
kidney4.6
liver2.1
lung8
lymph node13.2
ovary1.4
placenta4.7
prostate2.9
salivary gland3.5
skin3.1
small intestine8.1
spleen13.6
stomach5
testis1.4
thyroid gland17.2
urinary bladder14.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600554, gene) Interleukin 15; IL15OMIM


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