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> Protein (NX_P41208)
Protein (NX_P41208)
Protein
Gene SymbolCETN2 to neXtProt (NX_P41208)
DescriptionCentrin-2
ChromosomeX
LocationXq28 (151995517 ~ 151999321) to Ensembl
Sequene Features : Isoforms 1, Variants 27, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell division
.cellular protein metabolic process
.post-translational protein modification
  + 9 more...
.calcium ion binding .XPC complex
.ciliary basal body
.photoreceptor connecting cilium
  + 5 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 27 4
2014-09-19protein level
1 19 4
2014-05-27protein level
1 19 6
2014-02-25protein level
1 19 6
2013-12-09protein level
1 17 6
2013-11-01protein level
1 15 4
2013-09-12protein level
1 15 3
2013-08-17protein level
1 15 3
2013-07-15protein level
1 7 2
2013-06-11protein level
1 7 2
2013-02-12protein level
1 3 2
2012-12-20protein level
1 3 2
2012-10-30protein level
1 3 2
2012-10-07protein level
1 3 2
2012-08-24protein level
1 0 2
2012-07-28protein level
1 0 2
2012-06-08protein level
1 1 2
2012-05-07protein level
1 1 2
2012-04-10protein level
1 1 2
2012-01-13protein level
1 0 2
2011-12-20protein level
1 0 2
2011-11-11protein level
1 0 2
2011-08-23protein level
1 0 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P41208-1
6 0 1 19725.8193
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1789926,EBI-743371 SFI1  
  .negative regulation of phosphatase activity
.organelle organization
.mitotic cell cycle
.G2/M transition of mitotic cell cycle
.phosphatase binding .cytosol
.centriole
2 EBI-1789926,EBI-1566217 CCP110  
  .centrosome duplication
.regulation of cytokinesis
.cell projection organization
  + 4 more...
.N/A .protein complex
.cytosol
.centriole
.centrosome
3 EBI-1789926,EBI-372610 XPC  
  .regulation of mitotic cell cycle phase transition
.UV-damage excision repair
.cellular protein metabolic process
  + 10 more...
.single-stranded DNA binding
.damaged DNA binding
.bubble DNA binding
.heteroduplex DNA loop binding
.XPC complex
.extracellular exosome
.plasma membrane
  + 5 more...
4 EBI-1789926,EBI-10182463 SGSM1  
  .N/A .N/A .Golgi apparatus
5 EBI-1789926,EBI-2561090 POC5  
  .cell cycle .N/A .centriole
.centrosome
6 EBI-1789926,EBI-10171633 PNMA5  
  .positive regulation of apoptotic process .identical protein binding .N/A
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland91
ascites75
bladder167
blood32
bone83
bone marrow61
brain43
connective tissue40
ear248
embryonic tissue28
esophagus49
eye43
heart44
intestine30
kidney109
larynx42
liver48
lung98
lymph node22
mammary gland66
muscle37
nerve64
ovary108
pancreas28
pharynx343
pituitary gland121
placenta17
prostate36
salivary gland98
skin33
stomach41
testis27
thymus25
thyroid42
trachea38
umbilical cord72
uterus38
vascular58
Health State
TissuesTPM*
normal46
adrenal tumor158
bladder carcinoma284
breast (mammary gland) tumor53
chondrosarcoma84
colorectal tumor26
esophageal tumor57
gastrointestinal tumor59
germ cell tumor18
glioma83
head and neck tumor37
kidney tumor101
leukemia74
liver tumor52
lung tumor38
non-neoplasia10
ovarian tumor91
pancreatic tumor47
prostate cancer38
retinoblastoma43
skin tumor15
soft tissue/muscle tissue tumor39
uterine tumor44
Developmental Stage
TissuesTPM*
adult45
embryoid body42
blastocyst16
neonate32
fetus61
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue25.1
adrenal gland40.4
appendix19.7
bone marrow16.1
cerebral cortex34
colon25.2
duodenum14.4
esophagus37.2
gallbladder33.4
heart muscle26.2
kidney52.3
liver16.9
lung37.3
lymph node15.2
ovary51.7
pancreas9.9
placenta17.3
prostate46
salivary gland15.7
skin14.5
small intestine15.4
spleen13.7
stomach17.3
testis23.7
thyroid gland58.8
urinary bladder34.9
Tissues
TissuesExpression level
adrenal glandMedium
appendixLow
bone marrowLow
breastLow
bronchusHigh
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonLow
duodenumLow
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeHigh
gallbladderMedium
heart muscleLow
hippocampusMedium
kidneyHigh
lateral ventricleMedium
liverLow
lungMedium
nasopharynxHigh
oral mucosaMedium
ovaryMedium
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateLow
rectumLow
salivary glandLow
seminal vesicleMedium
skin 1Medium
skin 2Medium
small intestineLow
smooth muscleMedium
soft tissue 1Low
soft tissue 2Low
stomach 1Medium
stomach 2Medium
testisHigh
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*300006, gene) Centrin, ef-hand protein, 2; CETN2OMIM


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