Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_P42680)
Protein (NX_P42680)
Protein
Gene SymbolTEC to neXtProt (NX_P42680)
DescriptionTyrosine-protein kinase Tec
Chromosome4
Location4p11 (48137800 ~ 48271881) to Ensembl
Sequene Features : Isoforms 1, Variants 90, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.B cell receptor signaling pathway
.T cell receptor signaling pathway
.positive regulation of peptidyl-tyrosine phosphorylation
  + 12 more...
.metal ion binding
.phospholipid binding
.ATP binding
.non-membrane spanning protein tyrosine kinase activity
.extrinsic component of cytoplasmic side of plasma membrane
.cell-cell junction
.cytoskeleton
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 90 3
2014-09-19protein level
1 70 3
2014-05-27protein level
1 70 3
2014-02-25protein level
1 69 3
2013-12-09protein level
1 60 3
2013-11-01protein level
1 56 3
2013-09-12protein level
1 56 3
2013-08-17protein level
1 56 3
2013-07-15protein level
1 34 3
2013-06-11protein level
1 34 3
2013-02-12protein level
1 13 4
2012-12-20protein level
1 12 4
2012-10-30protein level
1 16 4
2012-10-07protein level
1 16 4
2012-08-24protein level
1 10 4
2012-07-28protein level
1 10 4
2012-06-08protein level
1 11 4
2012-05-07protein level
1 11 4
2012-04-10protein level
1 11 4
2012-01-13protein level
1 10 4
2011-12-20protein level
1 10 4
2011-11-11protein level
1 10 4
2011-08-23protein level
1 10 4
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P42680-1
32 0 0 73533.6693
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1383480,EBI-1039152 MET  
  .positive regulation of endothelial cell chemotaxis
.negative regulation of hydrogen peroxide-mediated programmed cell death
.semaphorin-plexin signaling pathway
  + 22 more...
.protein phosphatase binding
.ATP binding
.hepatocyte growth factor-activated receptor activity
.protein tyrosine kinase activity
.integral component of membrane
.cell surface
.basal plasma membrane
  + 3 more...
2 EBI-1383480,EBI-517684 GAB1  
  .interleukin-6-mediated signaling pathway
.labyrinthine layer development
.phosphatidylinositol-mediated signaling
  + 13 more...
.SH3/SH2 adaptor activity
.signal transducer activity
.cytosol
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
bone marrow61
heart11
intestine8
kidney9
lung2
lymph22
lymph node22
mammary gland6
muscle18
pancreas4
skin9
thyroid21
uterus8
Health State
TissuesTPM*
normal3
adrenal tumor158
breast (mammary gland) tumor10
colorectal tumor8
germ cell tumor7
head and neck tumor7
lymphoma13
pancreatic tumor9
uterine tumor22
Developmental Stage
TissuesTPM*
adult5
fetus3
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.1
adrenal gland2.8
appendix3.2
bone marrow7.4
colon1.9
duodenum1.7
esophagus4.6
gallbladder1.8
heart muscle1.3
kidney1.5
liver2.2
lung3.1
lymph node4
placenta1.7
prostate1
salivary gland2.3
skin4.1
small intestine2
spleen2.1
stomach2.2
testis2.2
thyroid gland1.7
urinary bladder1.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600583, gene) Tec protein tyrosine kinase; TECOMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center