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> Protein (NX_P43353)
Protein (NX_P43353)
Protein
Gene SymbolALDH3B1 to neXtProt (NX_P43353)
DescriptionAldehyde dehydrogenase family 3 member B1
Chromosome11
Location11q13.2 (67776048 ~ 67796744) to Ensembl
Sequene Features : Isoforms 2, Variants 0, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.oxidation-reduction process
.aldehyde catabolic process
.cellular response to oxidative stress
  + 3 more...
.aldehyde dehydrogenase [NAD(P)+] activity
.3-chloroallyl aldehyde dehydrogenase activity
.extracellular exosome
.vesicle
.plasma membrane
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 0 7
2014-09-19protein level
2 0 7
2014-05-27protein level
2 0 7
2014-02-25protein level
2 0 7
2013-12-09protein level
2 0 7
2013-11-01protein level
2 0 3
2013-09-12protein level
2 0 0
2013-08-17protein level
2 0 0
2013-07-15protein level
2 0 0
2013-06-11protein level
2 0 0
2013-02-12protein level
2 0 2
2012-12-20protein level
2 0 2
2012-10-30protein level
2 0 2
2012-10-07protein level
2 0 1
2012-08-24protein level
2 0 1
2012-07-28protein level
2 0 1
2012-06-08protein level
2 0 1
2012-05-07protein level
2 0 1
2012-04-10protein level
2 0 1
2012-01-13protein level
2 0 1
2011-12-20protein level
2 0 1
2011-11-11protein level
2 0 1
2011-08-23protein level
2 0 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P43353-1
2 15 3 51806.4114
NX_P43353-2
1 15 3 47652.2652
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2558314,EBI-10172150 KRTAP10-5  
  .N/A .identical protein binding .keratin filament
2 EBI-2558314,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
3 EBI-2558314,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
4 EBI-2558314,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
5 EBI-2558314,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
6 EBI-2558314,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
7 EBI-2558314,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites25
blood49
bone27
bone marrow41
cervix206
connective tissue6
eye47
heart11
intestine17
kidney56
lung131
lymph22
mammary gland26
muscle18
pancreas23
pharynx24
placenta17
prostate116
salivary gland246
skin14
spleen37
stomach10
testis4
thyroid21
uterus8
Health State
TissuesTPM*
normal14
breast (mammary gland) tumor10
cervical tumor202
chondrosarcoma84
colorectal tumor26
gastrointestinal tumor8
germ cell tumor11
head and neck tumor44
kidney tumor101
leukemia21
lung tumor253
lymphoma13
non-neoplasia31
pancreatic tumor47
prostate cancer211
retinoblastoma43
skin tumor15
uterine tumor22
Developmental Stage
TissuesTPM*
adult17
fetus12
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.6
adrenal gland11.8
appendix9.1
bone marrow24.7
cerebral cortex1.7
colon9.3
duodenum17.8
esophagus5.5
gallbladder8.2
heart muscle2.4
kidney18.2
liver2.3
lung42.5
lymph node4.8
ovary1.5
pancreas3.1
placenta10.2
prostate2.3
salivary gland4
skin3.4
small intestine14.6
spleen13.3
stomach17.7
testis2.6
thyroid gland1.7
urinary bladder12.3
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastLow
bronchusHigh
cerebellumMedium
cerebral cortexLow
cervix, uterineLow
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
fallopian tubeHigh
gallbladderMedium
heart muscleMedium
hippocampusLow
kidneyHigh
lateral ventricleMedium
liverMedium
lungMedium
nasopharynxHigh
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateMedium
rectumMedium
skeletal muscleLow
skin 1Medium
small intestineMedium
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Medium
spleenMedium
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandLow
urinary bladderMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600466, gene) Aldehyde dehydrogenase 3 family, member b1; ALDH3B1OMIM


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