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> Protein (NX_P43628)
Protein (NX_P43628)
Protein
Gene SymbolKIR2DL3 to neXtProt (NX_P43628)
DescriptionKiller cell immunoglobulin-like receptor 2DL3
Chromosome19
Location19q13.42 (55249980 ~ 55295776) to Ensembl
Sequene Features : Isoforms 2, Variants 81, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of immune response
.immune response
.receptor activity
.antigen binding
.integral component of membrane
.integral component of plasma membrane
.plasma membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 81 5
2014-09-19protein level
2 70 5
2014-05-27protein level
2 70 5
2014-02-25protein level
2 70 5
2013-12-09protein level
2 65 5
2013-11-01protein level
2 65 5
2013-09-12protein level
2 65 5
2013-08-17protein level
2 65 5
2013-07-15protein level
2 45 5
2013-06-11protein level
2 45 5
2013-02-12protein level
2 33 7
2012-12-20protein level
2 34 7
2012-10-30protein level
2 29 7
2012-10-07protein level
2 29 5
2012-08-24protein level
2 28 5
2012-07-28protein level
2 28 5
2012-06-08protein level
2 28 5
2012-05-07protein level
2 25 5
2012-04-10protein level
2 25 5
2012-01-13protein level
2 25 5
2011-12-20protein level
2 25 5
2011-11-11protein level
2 25 5
2011-08-23protein level
2 25 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P43628-1
1 4 10 37861.6468
NX_P43628-2
1 4 7 27251.6563
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-8632435,EBI-78260 PTPN6  
  .regulation of G1/S transition of mitotic cell cycle
.platelet aggregation
.regulation of ERK1 and ERK2 cascade
  + 33 more...
.protein kinase binding
.transmembrane receptor protein tyrosine phosphatase activity
.protein tyrosine phosphatase activity
.extracellular exosome
.alpha-beta T cell receptor complex
.membrane
  + 5 more...
2 EBI-8632435,EBI-297779 PTPN11  
  .positive regulation of glucose import in response to insulin stimulus
.positive regulation of ERK1 and ERK2 cascade
.regulation of type I interferon-mediated signaling pathway
  + 46 more...
.insulin receptor binding
.SH3/SH2 adaptor activity
.non-membrane spanning protein tyrosine phosphatase activity
  + 2 more...
.protein complex
.cytosol
.mitochondrion
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood16
Health State
TissuesTPM*
breast (mammary gland) tumor10
Developmental Stage
TissuesTPM*
adult2
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
spleen1.8
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*604938, gene) Killer cell immunoglobulin-like receptor, two domains, long cytoplasmicOMIM


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