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> Protein (NX_P45381)
Protein (NX_P45381)
Protein
Gene SymbolASPA to neXtProt (NX_P45381)
DescriptionAspartoacylase
Chromosome17
Location17p13.2 (3375668 ~ 3406713) to Ensembl
Sequene Features : Isoforms 1, Variants 71, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of oligodendrocyte differentiation
.central nervous system myelination
.aspartate catabolic process
.metal ion binding
.aspartoacylase activity
.hydrolase activity, acting on ester bonds
.aminoacylase activity
.extracellular exosome
.cytoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 71 0
2014-09-19protein level
1 63 0
2014-05-27protein level
1 63 0
2014-02-25protein level
1 63 0
2013-12-09protein level
1 56 0
2013-11-01protein level
1 55 0
2013-09-12protein level
1 55 0
2013-08-17protein level
1 55 0
2013-07-15protein level
1 47 0
2013-06-11protein level
1 47 0
2013-02-12protein level
1 40 0
2012-12-20protein level
1 40 0
2012-10-30protein level
1 40 0
2012-10-07protein level
1 40 0
2012-08-24protein level
1 40 0
2012-07-28protein level
1 40 0
2012-06-08protein level
1 46 0
2012-05-07protein level
1 43 0
2012-04-10protein level
1 43 0
2012-01-13protein level
1 40 0
2011-12-20protein level
1 40 0
2011-11-11protein level
1 40 0
2011-08-23protein level
1 40 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P45381-1
17 0 0 35711.9859
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-750475,EBI-3916242 ACY3  
  .small molecule metabolic process
.viral process
.xenobiotic metabolic process
.metal ion binding
.hydrolase activity, acting on ester bonds
.aminoacylase activity
.extracellular exosome
.apical plasma membrane
.cytosol
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
brain21
kidney52
mammary gland6
muscle28
skin18
stomach10
testis4
trachea19
uterus4
Health State
TissuesTPM*
normal12
adrenal tumor79
gastrointestinal tumor8
uterine tumor11
Developmental Stage
TissuesTPM*
adult5
fetus5
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue11.5
adrenal gland4.7
appendix2
cerebral cortex14.1
colon5.3
duodenum12
esophagus6.1
gallbladder4
heart muscle1.5
kidney33.9
liver8.1
lung3.3
lymph node1.8
ovary2.7
placenta2.3
prostate3.5
salivary gland1.4
skin4.1
small intestine12.6
spleen4.4
stomach3.6
testis5.9
thyroid gland1.6
urinary bladder5.8
Tissues
TissuesExpression level
adrenal glandLow
appendixMedium
bone marrowMedium
bronchusLow
cerebellumMedium
cerebral cortexMedium
cervix, uterineLow
colonMedium
duodenumMedium
epididymisMedium
gallbladderMedium
heart muscleMedium
hippocampusMedium
kidneyHigh
lateral ventricleMedium
liverMedium
lymph nodeMedium
nasopharynxLow
oral mucosaLow
pancreasLow
parathyroid glandLow
placentaMedium
prostateMedium
rectumMedium
seminal vesicleLow
skeletal muscleLow
small intestineMedium
smooth muscleLow
soft tissue 1Low
spleenMedium
stomach 1Medium
stomach 2Medium
testisLow
thyroid glandMedium
tonsilMedium
urinary bladderMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#271900, phenotype) Canavan diseaseOMIM
2(*608034, gene) Aspartoacylase; ASPAOMIM


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