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> Protein (NX_P46821)
Protein (NX_P46821)
Protein
Gene SymbolMAP1B to neXtProt (NX_P46821)
DescriptionMicrotubule-associated protein 1B
Chromosome5
Location5q13.2 (71403061 ~ 71505395) to Ensembl
Sequene Features : Isoforms 1, Variants 272, PTMs 98 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.establishment of monopolar cell polarity
.axon extension
.mitochondrion transport along microtubule
  + 5 more...
.structural molecule activity .dendritic spine
.cell junction
.postsynaptic density
  + 5 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 272 98
2014-09-19protein level
1 210 99
2014-05-27protein level
1 210 99
2014-02-25protein level
1 209 99
2013-12-09protein level
1 169 99
2013-11-01protein level
1 165 97
2013-09-12protein level
1 165 107
2013-08-17protein level
1 165 107
2013-07-15protein level
1 119 107
2013-06-11protein level
1 119 107
2013-02-12protein level
1 63 102
2012-12-20protein level
1 64 102
2012-10-30protein level
1 77 102
2012-10-07protein level
1 77 102
2012-08-24protein level
1 72 102
2012-07-28protein level
1 71 102
2012-06-08protein level
1 71 101
2012-05-07protein level
1 53 101
2012-04-10protein level
1 53 101
2012-01-13protein level
1 24 101
2011-12-20protein level
1 24 101
2011-11-11protein level
1 24 97
2011-08-23protein level
1 24 97
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P46821-1
108 0 2 270467.2559
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-764611,EBI-366083 TP53  
  .positive regulation of intrinsic apoptotic signaling pathway
.positive regulation of reactive oxygen species metabolic process
.negative regulation of reactive oxygen species metabolic process
  + 99 more...
.protein phosphatase 2A binding
.chaperone binding
.protein N-terminus binding
  + 27 more...
.protein complex
.PML body
.nuclear matrix
  + 11 more...
2 EBI-9517186,EBI-5323863 LRRK2  
  .negative regulation of peroxidase activity
.regulation of synaptic vesicle exocytosis
.regulation of branching morphogenesis of a nerve
  + 64 more...
.protein kinase A binding
.ion channel binding
.protein homodimerization activity
  + 18 more...
.extracellular exosome
.membrane raft
.perikaryon
  + 25 more...
3 EBI-764611,EBI-764342 GAN  
  .protein ubiquitination
.cytoskeleton organization
.N/A .Cul3-RING ubiquitin ligase complex
.cytoskeleton
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
adrenal gland30
bladder33
blood24
bone167
bone marrow82
brain490
connective tissue73
ear372
embryonic tissue192
esophagus148
eye296
heart111
intestine43
kidney151
larynx42
liver58
lung131
lymph node22
mammary gland66
muscle84
nerve514
ovary78
pancreas28
pituitary gland302
placenta14
prostate448
salivary gland49
skin47
spleen18
stomach10
testis45
trachea77
umbilical cord145
uterus94
vascular290
Health State
TissuesTPM*
normal246
breast (mammary gland) tumor53
chondrosarcoma205
colorectal tumor8
esophageal tumor173
gastrointestinal tumor25
germ cell tumor182
glioma195
head and neck tumor14
kidney tumor290
leukemia31
liver tumor83
lung tumor243
non-neoplasia248
ovarian tumor91
pancreatic tumor19
primitive neuroectodermal tumor of the CNS125
prostate cancer125
retinoblastoma279
soft tissue/muscle tissue tumor79
uterine tumor55
Developmental Stage
TissuesTPM*
adult212
embryoid body285
blastocyst97
neonate64
fetus405
infant212
juvenile143
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue19.5
adrenal gland19.1
appendix11.1
cerebral cortex103.7
colon5.9
duodenum1.8
esophagus12.6
gallbladder12.1
heart muscle15.3
kidney2.4
liver1.4
lung2.6
lymph node2.2
ovary6.9
pancreas1.7
placenta5.4
prostate16.4
salivary gland5.6
skin9
small intestine2.7
stomach3.3
testis13.6
thyroid gland5.8
urinary bladder15.1
Tissues
TissuesExpression level
adrenal glandLow
breastLow
bronchusMedium
cerebellumMedium
cerebral cortexHigh
colonMedium
fallopian tubeLow
hippocampusMedium
kidneyMedium
lateral ventricleLow
nasopharynxMedium
pancreasMedium
placentaLow
prostateLow
skin 1Low
smooth muscleLow
soft tissue 1Medium
soft tissue 2High
testisMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*157129, gene) Microtubule-associated protein 1b; MAP1BOMIM


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