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> Protein (NX_P48167)
Protein (NX_P48167)
Protein
Gene SymbolGLRB to neXtProt (NX_P48167)
DescriptionGlycine receptor subunit beta
Chromosome4
Location4q32.1 (157997209 ~ 158093242) to Ensembl
Sequene Features : Isoforms 2, Variants 90, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.chloride transmembrane transport
.righting reflex
.synaptic transmission, glycinergic
  + 12 more...
.extracellular-glycine-gated chloride channel activity
.extracellular-glycine-gated ion channel activity
.glycine binding
.drug binding
.postsynaptic membrane
.chloride channel complex
.cell junction
  + 2 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 90 5
2014-09-19protein level
2 62 5
2014-05-27protein level
2 62 5
2014-02-25protein level
2 60 5
2013-12-09protein level
2 53 5
2013-11-01protein level
2 46 5
2013-09-12protein level
2 46 5
2013-08-17protein level
2 46 5
2013-07-15protein level
2 29 3
2013-06-11protein level
2 29 3
2013-02-12protein level
1 16 3
2012-12-20protein level
1 15 3
2012-10-30protein level
1 16 3
2012-10-07protein level
1 16 3
2012-08-24protein level
1 14 3
2012-07-28protein level
1 13 3
2012-06-08protein level
1 14 3
2012-05-07protein level
1 7 3
2012-04-10protein level
1 7 3
2012-01-13protein level
1 2 3
2011-12-20protein level
1 2 3
2011-11-11protein level
1 2 3
2011-08-23protein level
1 2 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P48167-1
7 16 0 56085.9719
NX_P48167-2
0 16 0 34920.8644
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bone27
brain75
connective tissue26
eye4
heart44
kidney47
liver4
lung32
mammary gland26
muscle9
nerve64
ovary39
pancreas37
pituitary gland60
prostate5
salivary gland49
skin9
testis6
thyroid21
trachea19
uterus12
Health State
TissuesTPM*
normal23
adrenal tumor79
breast (mammary gland) tumor21
chondrosarcoma12
germ cell tumor18
glioma27
head and neck tumor7
kidney tumor72
lung tumor29
non-neoplasia20
ovarian tumor52
soft tissue/muscle tissue tumor23
uterine tumor33
Developmental Stage
TissuesTPM*
adult17
neonate32
fetus16
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.8
adrenal gland8.3
appendix1.4
cerebral cortex37.9
colon1.1
duodenum1
esophagus1.5
gallbladder4.2
heart muscle9.6
kidney3.1
lung3.7
ovary1.5
pancreas7.2
placenta2.8
prostate6
salivary gland15.6
small intestine1
stomach1.1
testis1.9
thyroid gland1.2
urinary bladder2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*138492, gene) Glycine receptor, beta subunit; GLRBOMIM
2(#614619, phenotype) Hyperekplexia 2; HKPX2OMIM


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