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> Protein (NX_P48594)
Protein (NX_P48594)
Protein
Gene SymbolSERPINB4 to neXtProt (NX_P48594)
DescriptionSerpin B4
Chromosome18
Location18q21.33 (61304493 ~ 61311532) to Ensembl
Sequene Features : Isoforms 1, Variants 104, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.protection from natural killer cell mediated cytotoxicity
.regulation of proteolysis
.negative regulation of endopeptidase activity
.negative regulation of peptidase activity
.enzyme binding
.serine-type endopeptidase inhibitor activity
.protease binding
.extracellular exosome
.cytoplasm
.intracellular
.extracellular space
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 104 1
2014-09-19protein level
1 81 1
2014-05-27protein level
1 81 2
2014-02-25protein level
1 80 2
2013-12-09protein level
1 66 2
2013-11-01protein level
1 59 2
2013-09-12protein level
1 59 2
2013-08-17protein level
1 59 2
2013-07-15protein level
1 43 2
2013-06-11protein level
1 43 2
2013-02-12protein level
1 18 2
2012-12-20protein level
1 18 2
2012-10-30protein level
1 21 2
2012-10-07protein level
1 21 2
2012-08-24protein level
1 13 2
2012-07-28protein level
1 13 2
2012-06-08protein level
1 13 2
2012-05-07protein level
1 10 2
2012-04-10protein level
1 10 2
2012-01-13protein level
1 3 2
2011-12-20protein level
1 3 2
2011-11-11protein level
1 3 2
2011-08-23protein level
1 3 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P48594-1
10 0 10 44825.3512
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone marrow123
cervix61
esophagus446
larynx85
lung20
mouth60
muscle18
pharynx196
salivary gland98
skin4
testis2
thymus12
trachea289
uterus64
Health State
TissuesTPM*
normal6
esophageal tumor347
germ cell tumor3
head and neck tumor44
leukemia63
skin tumor7
uterine tumor144
Developmental Stage
TissuesTPM*
adult13
fetus1
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
appendix3.1
esophagus90.8
skin6.9
urinary bladder20.2
Tissues
TissuesExpression level
bronchusHigh
cervix, uterineMedium
esophagusMedium
nasopharynxHigh
oral mucosaLow
skin 1Medium
skin 2Medium
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600518, gene) Serpin peptidase inhibitor, clade b (ovalbumin), member 4; SERPINB4OMIM


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