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> Protein (NX_P49638)
Protein (NX_P49638)
Protein
Gene SymbolTTPA to neXtProt (NX_P49638)
DescriptionAlpha-tocopherol transfer protein
Chromosome8
Location8q12.3 (63961112 ~ 63998612) to Ensembl
Sequene Features : Isoforms 1, Variants 44, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of establishment of blood-brain barrier
.negative regulation of cell death
.intracellular pH reduction
  + 9 more...
.phosphatidylinositol-3,4-bisphosphate binding
.vitamin E binding
.phosphatidylinositol-4,5-bisphosphate binding
.transporter activity
.cytosol
.late endosome
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 44 1
2014-09-19protein level
1 36 1
2014-05-27protein level
1 36 1
2014-02-25protein level
1 35 1
2013-12-09protein level
1 31 1
2013-11-01protein level
1 31 1
2013-09-12protein level
1 31 1
2013-08-17protein level
1 31 1
2013-07-15protein level
1 25 1
2013-06-11protein level
1 25 1
2013-02-12protein level
1 12 0
2012-12-20protein level
1 12 0
2012-10-30protein level
1 13 0
2012-10-07protein level
1 13 0
2012-08-24protein level
1 12 0
2012-07-28protein level
1 12 0
2012-06-08protein level
1 13 0
2012-05-07protein level
1 13 0
2012-04-10protein level
1 13 0
2012-01-13protein level
1 9 0
2011-12-20protein level
1 9 0
2011-11-11protein level
1 9 0
2011-08-23protein level
1 9 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P49638-1
13 0 0 31729.557
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10210710,EBI-2548702 CMTM5  
  .negative regulation of myoblast differentiation
.chemotaxis
.N/A .integral component of membrane
.extracellular space
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain1
intestine4
kidney9
liver4
mammary gland13
placenta3
testis4
Health State
TissuesTPM*
normal2
breast (mammary gland) tumor21
germ cell tumor11
liver tumor10
Developmental Stage
TissuesTPM*
adult2
fetus7
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.3
cerebral cortex1.9
colon3.2
kidney2.7
liver69
placenta1.6
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(#277460, phenotype) Vitamin e, familial isolated deficiency of; VEDOMIM
2(*600415, gene) Tocopherol transfer protein, alpha; TTPAOMIM


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