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> Protein (NX_P49721)
Protein (NX_P49721)
Protein
Gene SymbolPSMB2 to neXtProt (NX_P49721)
DescriptionProteasome subunit beta type-2
Chromosome1
Location1p34.3 (36067185 ~ 36107445) to Ensembl
Sequene Features : Isoforms 1, Variants 12, PTMs 10 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 25 more...
.threonine-type endopeptidase activity
.endopeptidase activity
.extracellular exosome
.membrane
.proteasome core complex
  + 5 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 12 10
2014-09-19protein level
1 9 10
2014-05-27protein level
1 9 10
2014-02-25protein level
1 9 10
2013-12-09protein level
1 10 10
2013-11-01protein level
1 9 10
2013-09-12protein level
1 9 10
2013-08-17protein level
1 9 10
2013-07-15protein level
1 8 1
2013-06-11protein level
1 8 1
2013-02-12protein level
1 6 4
2012-12-20protein level
1 6 4
2012-10-30protein level
1 5 4
2012-10-07protein level
1 5 4
2012-08-24protein level
1 3 4
2012-07-28protein level
1 3 4
2012-06-08protein level
1 3 4
2012-05-07protein level
1 3 4
2012-04-10protein level
1 3 4
2012-01-13protein level
1 7 4
2011-12-20protein level
1 7 4
2011-11-11protein level
1 7 3
2011-08-23protein level
1 7 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P49721-1
9 0 0 22821.6142
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-359335,EBI-603340 PSMB3  
  .positive regulation of canonical Wnt signaling pathway
.negative regulation of canonical Wnt signaling pathway
.regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
  + 23 more...
.threonine-type endopeptidase activity
.endopeptidase activity
.extracellular exosome
.actin cytoskeleton
.proteasome core complex
  + 7 more...
2 EBI-359335,EBI-4397613 KCTD9  
  .protein homooligomerization .N/A .N/A
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland121
ascites100
bladder100
blood147
bone83
bone marrow205
brain162
cervix185
connective tissue140
embryonic tissue84
esophagus248
eye81
heart111
intestine146
kidney128
larynx42
liver82
lung104
lymph180
lymph node100
mammary gland112
mouth181
muscle112
nerve64
ovary246
pancreas131
parathyroid194
pharynx220
placenta91
prostate68
skin208
spleen280
stomach135
testis121
thymus276
thyroid42
trachea96
uterus124
vascular174
Health State
TissuesTPM*
normal128
adrenal tumor79
bladder carcinoma227
breast (mammary gland) tumor96
cervical tumor202
chondrosarcoma72
colorectal tumor159
esophageal tumor289
gastrointestinal tumor118
germ cell tumor246
glioma74
head and neck tumor82
kidney tumor101
leukemia137
liver tumor114
lung tumor136
lymphoma166
non-neoplasia51
ovarian tumor249
pancreatic tumor133
primitive neuroectodermal tumor of the CNS118
prostate cancer38
retinoblastoma64
skin tumor143
soft tissue/muscle tissue tumor231
uterine tumor77
Developmental Stage
TissuesTPM*
adult121
embryoid body85
blastocyst48
neonate354
fetus104
infant42
juvenile341
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue23.1
adrenal gland24.9
appendix29.6
bone marrow27.8
cerebral cortex25.6
colon29.5
duodenum24.8
esophagus28.5
gallbladder23.4
heart muscle20.3
kidney20.5
liver27.4
lung23.9
lymph node34.4
ovary22.1
pancreas10.9
placenta32.6
prostate22.9
salivary gland16.3
skin25.7
small intestine25.6
spleen24.6
stomach22.3
testis20
thyroid gland24.7
urinary bladder28.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602175, gene) Proteasome subunit, beta-type, 2; PSMB2OMIM


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