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> Protein (NX_P49796)
Protein (NX_P49796)
Protein
Gene SymbolRGS3 to neXtProt (NX_P49796)
DescriptionRegulator of G-protein signaling 3
Chromosome9
Location9q32 (116207011 ~ 116360018) to Ensembl
Sequene Features : Isoforms 9, Variants 179, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of GTPase activity
.termination of G-protein coupled receptor signaling pathway
.regulation of G-protein coupled receptor protein signaling pathway
.inactivation of MAPK activity
.GTPase activator activity .plasma membrane
.cytosol
.cytoplasm
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
9 179 5
2014-09-19protein level
9 144 5
2014-05-27protein level
9 144 5
2014-02-25protein level
8 143 4
2013-12-09protein level
7 96 4
2013-11-01protein level
7 94 4
2013-09-12protein level
7 94 5
2013-08-17protein level
7 94 5
2013-07-15protein level
6 67 5
2013-06-11protein level
6 67 5
2013-02-12protein level
6 34 8
2012-12-20protein level
6 32 8
2012-10-30protein level
6 40 8
2012-10-07protein level
6 40 2
2012-08-24protein level
6 40 2
2012-07-28protein level
6 40 2
2012-06-08protein level
6 51 2
2012-05-07protein level
6 41 2
2012-04-10protein level
6 41 2
2012-01-13protein level
6 21 2
2011-12-20protein level
6 21 2
2011-11-11protein level
6 21 2
2011-08-23protein level
6 21 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P49796-1
0 26 0 56566.2601
NX_P49796-2
1 10 0 23710.108
NX_P49796-3
5 59 0 132251.8404
NX_P49796-4
0 47 0 100883.6806
NX_P49796-5
3 31 0 67239.4385
NX_P49796-6
1 59 0 120931.3459
NX_P49796-7
0 15 0 35085.1095
NX_P49796-8
1 15 0 36079.495
NX_P49796-9
0 31 0 66435.7137
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2107809,EBI-740019 PLSCR1  
  .positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity
.regulation of Fc receptor mediated stimulatory signaling pathway
.defense response to virus
  + 11 more...
.CD4 receptor binding
.enzyme binding
.phospholipid scramblase activity
  + 5 more...
.extracellular exosome
.membrane raft
.extracellular matrix
  + 7 more...
2 EBI-10211517,EBI-739467 GORASP2  
  .organelle organization
.mitotic cell cycle
.N/A .membrane
.Golgi apparatus
.Golgi membrane
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites50
bladder66
blood16
bone139
brain69
cervix20
connective tissue127
ear62
embryonic tissue51
eye105
heart89
intestine43
kidney85
liver19
lung56
lymph67
lymph node66
mammary gland33
mouth45
muscle18
nerve128
ovary39
pancreas23
pituitary gland60
placenta24
prostate31
salivary gland345
skin113
spleen187
stomach10
testis73
thymus62
thyroid64
trachea77
uterus38
vascular77
Health State
TissuesTPM*
normal64
adrenal tumor79
breast (mammary gland) tumor42
cervical tumor28
chondrosarcoma144
colorectal tumor53
gastrointestinal tumor16
germ cell tumor34
glioma74
head and neck tumor82
kidney tumor116
leukemia31
liver tumor10
lung tumor48
lymphoma41
non-neoplasia144
ovarian tumor13
pancreatic tumor28
primitive neuroectodermal tumor of the CNS78
prostate cancer28
retinoblastoma21
skin tumor111
soft tissue/muscle tissue tumor47
uterine tumor11
Developmental Stage
TissuesTPM*
adult48
embryoid body71
blastocyst48
fetus52
juvenile53
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue37.8
adrenal gland26.3
appendix19
bone marrow7.9
cerebral cortex10.1
colon17.2
duodenum16.3
esophagus10.2
gallbladder46
heart muscle73.5
kidney34.8
liver19.5
lung43.1
lymph node27.5
ovary4.3
pancreas11.1
placenta24.4
prostate22.7
salivary gland8.6
skin7.5
small intestine17.5
spleen24.2
stomach17.6
testis25.4
thyroid gland16.9
urinary bladder33.4
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowLow
breastMedium
bronchusMedium
cerebellumHigh
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderMedium
heart muscleMedium
hippocampusHigh
kidneyMedium
lateral ventricleHigh
liverMedium
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryLow
pancreasHigh
parathyroid glandMedium
placentaMedium
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineMedium
smooth muscleMedium
soft tissue 1Low
soft tissue 2Low
spleenMedium
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602189, gene) Regulator of g protein signaling 3; RGS3OMIM


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