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> Protein (NX_P49901)
Protein (NX_P49901)
Protein
Gene SymbolSMCP to neXtProt (NX_P49901)
DescriptionSperm mitochondrial-associated cysteine-rich protein
Chromosome1
Location1q21.3 (152850793 ~ 152857523) to Ensembl
Sequene Features : Isoforms 1, Variants 15, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.sperm motility
.penetration of zona pellucida
.N/A .mitochondrial membrane
.mitochondrion
.cytoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 15 0
2014-09-19protein level
1 11 0
2014-05-27transcript level
1 11 0
2014-02-25transcript level
1 11 0
2013-12-09transcript level
1 10 0
2013-11-01transcript level
1 10 0
2013-09-12transcript level
1 10 0
2013-08-17transcript level
1 10 0
2013-07-15transcript level
1 9 0
2013-06-11transcript level
1 9 0
2013-02-12transcript level
1 4 0
2012-12-20transcript level
1 4 0
2012-10-30transcript level
1 4 0
2012-10-07transcript level
1 4 0
2012-08-24transcript level
1 4 0
2012-07-28transcript level
1 4 0
2012-06-08transcript level
1 5 0
2012-05-07transcript level
1 5 0
2012-04-10transcript level
1 5 0
2012-01-13transcript level
1 6 0
2011-12-20transcript level
1 6 0
2011-11-11transcript level
1 6 0
2011-08-23transcript level
1 6 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P49901-1
7 0 0 12758.4354
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-750494,EBI-533224 TCF4  
  .protein-DNA complex assembly
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 3 more...
.E-box binding
.protein heterodimerization activity
.bHLH transcription factor binding
  + 9 more...
.transcription factor complex
.nucleus
2 EBI-750494,EBI-3958099 KRTAP5-9  
  .epidermis development .N/A .keratin filament
3 EBI-750494,EBI-10172150 KRTAP10-5  
  .N/A .identical protein binding .keratin filament
4 EBI-750494,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
5 EBI-750494,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
6 EBI-750494,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
7 EBI-750494,EBI-618309 GOLGA2  
  .negative regulation of protein binding
.mitotic cell cycle
.syntaxin binding
.protein kinase binding
.Golgi cisterna membrane
.ER to Golgi transport vesicle
.cis-Golgi network
  + 4 more...
8 EBI-750494,EBI-739580 CALCOCO2  
  .response to interferon-gamma
.viral process
.protein homodimerization activity .perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.membrane
  + 4 more...
9 EBI-750494,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
10 EBI-750494,EBI-10246358 LCE4A  
  .keratinization .N/A .N/A
11 EBI-750494,EBI-10250562 KRTAP5-6  
  .N/A .N/A .keratin filament
12 EBI-750494,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
13 EBI-750494,EBI-739863 KRTAP4-12  
  .N/A .N/A .keratin filament
14 EBI-750494,EBI-10185730 KRTAP9-4  
  .N/A .N/A .keratin filament
15 EBI-750494,EBI-1044640 KRTAP9-2  
  .N/A .N/A .keratin filament
16 EBI-750494,EBI-10302392 KRTAP4-11  
  .N/A .N/A .keratin filament
17 EBI-750494,EBI-10302547 KRTAP4-7  
  .hair cycle
.aging
.N/A .keratin filament
18 EBI-750494,EBI-3918154 RGS17  
  .positive regulation of GTPase activity
.termination of G-protein coupled receptor signaling pathway
.GTPase activator activity .plasma membrane
.cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
brain2
nerve64
placenta10
testis140
Health State
TissuesTPM*
normal8
germ cell tumor11
leukemia10
Developmental Stage
TissuesTPM*
adult5
fetus8
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
testis338.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*601148, gene) Sperm mitochondria-associated cysteine-rich protein; SMCPOMIM


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