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> Protein (NX_P50151)
Protein (NX_P50151)
Protein
Gene SymbolGNG10 to neXtProt (NX_P50151)
DescriptionGuanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-10
Chromosome9
Location9q31.3 (114423615 ~ 114432526) to Ensembl
Sequene Features : Isoforms 1, Variants 4, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to glucagon stimulus
.small molecule metabolic process
.synaptic transmission
  + 3 more...
.signal transducer activity
.GTPase activity
.extracellular exosome
.plasma membrane
.heterotrimeric G-protein complex
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 4 3
2014-09-19protein level
1 3 3
2014-05-27protein level
1 3 3
2014-02-25protein level
1 3 3
2013-12-09protein level
1 3 3
2013-11-01protein level
1 2 3
2013-09-12protein level
1 2 2
2013-08-17protein level
1 2 2
2013-07-15protein level
1 1 2
2013-06-11protein level
1 1 2
2013-02-12protein level
1 1 2
2012-12-20protein level
1 0 2
2012-10-30protein level
1 1 2
2012-10-07protein level
1 1 2
2012-08-24protein level
1 1 2
2012-07-28protein level
1 1 2
2012-06-08protein level
1 1 2
2012-05-07protein level
1 1 2
2012-04-10protein level
1 1 2
2012-01-13protein level
1 2 2
2011-12-20protein level
1 2 2
2011-11-11protein level
1 2 2
2011-08-23protein level
1 2 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P50151-1
1 0 2 7200.6558
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10211741,EBI-1047263 KRT38  
  .N/A .structural molecule activity .extracellular exosome
.intermediate filament
2 EBI-10211741,EBI-533224 TCF4  
  .protein-DNA complex assembly
.positive regulation of transcription from RNA polymerase II promoter
.positive regulation of transcription, DNA-templated
  + 3 more...
.E-box binding
.protein heterodimerization activity
.bHLH transcription factor binding
  + 9 more...
.transcription factor complex
.nucleus
3 EBI-10211741,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites25
bladder66
blood65
bone69
bone marrow20
brain49
connective tissue80
ear62
embryonic tissue37
eye28
heart11
intestine47
kidney4
liver48
lung2
lymph22
lymph node33
mammary gland46
mouth75
muscle9
pancreas9
pharynx73
pituitary gland60
placenta7
prostate68
salivary gland98
skin4
spleen18
stomach52
testis2
thyroid42
uterus4
vascular38
Health State
TissuesTPM*
normal2
adrenal tumor79
bladder carcinoma227
breast (mammary gland) tumor64
chondrosarcoma132
colorectal tumor44
gastrointestinal tumor50
germ cell tumor3
glioma55
head and neck tumor52
kidney tumor14
leukemia10
liver tumor20
lung tumor9
lymphoma13
non-neoplasia10
ovarian tumor13
pancreatic tumor66
primitive neuroectodermal tumor of the CNS62
prostate cancer28
retinoblastoma21
skin tumor31
soft tissue/muscle tissue tumor111
uterine tumor44
Developmental Stage
TissuesTPM*
adult3
embryoid body71
blastocyst16
neonate64
fetus50
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue37.2
adrenal gland28.9
appendix34
bone marrow13.9
cerebral cortex22.8
colon19.7
duodenum11.3
esophagus17.2
gallbladder20.5
heart muscle13.7
kidney17.8
liver15.8
lung20.9
lymph node22.4
ovary11.3
pancreas7.4
placenta22.2
prostate36.1
salivary gland14.6
skin5.9
small intestine18.8
spleen12.6
stomach10.9
testis11.1
thyroid gland11.4
urinary bladder34.3
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*604389, gene) Guanine nucleotide-binding protein, gamma-10; GNG10OMIM


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