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> Protein (NX_P50452)
Protein (NX_P50452)
Protein
Gene SymbolSERPINB8 to neXtProt (NX_P50452)
DescriptionSerpin B8
Chromosome18
Location18q22.1 (61637159 ~ 61672278) to Ensembl
Sequene Features : Isoforms 3, Variants 78, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.negative regulation of endopeptidase activity .serine-type endopeptidase inhibitor activity .extracellular exosome
.cytosol
.extracellular space
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 78 0
2014-09-19protein level
3 64 0
2014-05-27protein level
2 64 0
2014-02-25protein level
2 64 0
2013-12-09protein level
2 51 0
2013-11-01protein level
2 51 0
2013-09-12protein level
2 51 0
2013-08-17protein level
2 51 0
2013-07-15protein level
2 33 0
2013-06-11protein level
2 33 0
2013-02-12protein level
2 20 0
2012-12-20protein level
2 18 0
2012-10-30protein level
2 21 0
2012-10-07protein level
2 21 0
2012-08-24protein level
2 21 0
2012-07-28protein level
2 21 0
2012-06-08protein level
2 21 0
2012-05-07protein level
2 17 0
2012-04-10protein level
2 17 0
2012-01-13protein level
1 9 0
2011-12-20protein level
1 9 0
2011-11-11protein level
1 9 0
2011-08-23protein level
1 9 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P50452-1
0 15 3 42739.075
NX_P50452-2
1 9 2 27654.5195
NX_P50452-3
0 6 1 22119.043
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder33
bone27
brain7
cervix20
connective tissue46
embryonic tissue9
eye4
heart33
intestine21
kidney18
liver4
lung20
mouth45
muscle18
ovary9
pancreas23
pharynx24
placenta14
prostate10
salivary gland49
skin56
stomach10
testis2
thymus37
trachea19
uterus30
vascular96
Health State
TissuesTPM*
normal14
bladder carcinoma56
cervical tumor28
chondrosarcoma48
colorectal tumor17
gastrointestinal tumor8
germ cell tumor3
head and neck tumor22
kidney tumor14
liver tumor10
lymphoma13
non-neoplasia41
ovarian tumor13
pancreatic tumor9
prostate cancer19
skin tumor31
soft tissue/muscle tissue tumor23
uterine tumor33
Developmental Stage
TissuesTPM*
adult19
embryoid body28
neonate32
fetus14
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue9.3
adrenal gland9.7
appendix15.8
bone marrow17.5
cerebral cortex4.8
colon8.8
duodenum6.5
esophagus33.5
gallbladder19.6
heart muscle2.6
kidney2.8
liver24.8
lung9
lymph node12.8
ovary4.1
pancreas3.3
placenta9.2
prostate3.3
salivary gland1.6
skin32.2
small intestine6.5
spleen7.5
stomach6.9
testis3.4
thyroid gland6.3
urinary bladder18
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*601697, gene) Protease inhibitor 8; PI8OMIM


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