Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_P50539)
Protein (NX_P50539)
Protein
Gene SymbolMXI1 to neXtProt (NX_P50539)
DescriptionMax-interacting protein 1
Chromosome10
Location10q25.2 (111967363 ~ 112047123) to Ensembl
Sequene Features : Isoforms 4, Variants 21, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cytoplasmic sequestering of transcription factor
.negative regulation of cell proliferation
.transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.transcription corepressor activity
.DNA binding
.cytoplasm
.nucleolus
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 21 1
2014-09-19protein level
4 20 1
2014-05-27protein level
4 20 1
2014-02-25protein level
4 20 1
2013-12-09protein level
4 16 1
2013-11-01protein level
4 15 1
2013-09-12protein level
4 15 1
2013-08-17protein level
4 15 1
2013-07-15protein level
4 10 0
2013-06-11protein level
4 10 0
2013-02-12protein level
4 6 0
2012-12-20protein level
4 6 0
2012-10-30protein level
4 6 0
2012-10-07protein level
4 6 0
2012-08-24protein level
4 6 0
2012-07-28protein level
4 6 0
2012-06-08protein level
4 5 0
2012-05-07protein level
4 5 0
2012-04-10protein level
3 5 0
2012-01-13protein level
3 3 0
2011-12-20protein level
3 3 0
2011-11-11protein level
3 3 0
2011-08-23protein level
3 3 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P50539-1
2 9 0 26046.0146
NX_P50539-2
0 9 0 21753.9227
NX_P50539-3
4 9 0 32799.4067
NX_P50539-4
0 8 0 20545.3365
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-752241,EBI-7416931 ENTPD5  
  .'de novo' posttranslational protein folding
.ATP metabolic process
.positive regulation of glycolytic process
  + 4 more...
.uridine-diphosphatase activity
.guanosine-diphosphatase activity
.extracellular exosome
.endoplasmic reticulum
2 EBI-10211940,EBI-10172150 KRTAP10-5  
  .N/A .identical protein binding .keratin filament
3 EBI-10211940,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
4 EBI-10211940,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
5 EBI-10211940,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
6 EBI-752241,EBI-751711 MAX  
  .cellular response to peptide hormone stimulus
.retina development in camera-type eye
.neuron apoptotic process
  + 6 more...
.sequence-specific DNA binding
.transcription coactivator activity
.transcription cofactor activity
.sequence-specific DNA binding transcription factor activity
.MLL1 complex
.dendrite
.PML body
  + 3 more...
7 EBI-10211940,EBI-739580 CALCOCO2  
  .response to interferon-gamma
.viral process
.protein homodimerization activity .perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.membrane
  + 4 more...
8 EBI-10211940,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
9 EBI-10211940,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland151
blood24
bone55
bone marrow61
brain77
cervix82
connective tissue13
ear124
embryonic tissue42
eye67
heart33
intestine21
kidney28
larynx42
liver38
lung47
lymph22
lymph node11
mammary gland26
muscle75
nerve64
ovary29
pancreas60
parathyroid97
pharynx24
pituitary gland121
placenta17
prostate21
salivary gland49
skin47
spleen18
stomach31
testis36
thyroid64
trachea19
uterus30
Health State
TissuesTPM*
normal49
breast (mammary gland) tumor32
cervical tumor57
chondrosarcoma36
gastrointestinal tumor25
germ cell tumor18
head and neck tumor22
kidney tumor29
liver tumor41
lung tumor19
lymphoma69
non-neoplasia82
ovarian tumor13
pancreatic tumor57
primitive neuroectodermal tumor of the CNS7
prostate cancer28
retinoblastoma21
skin tumor63
soft tissue/muscle tissue tumor15
uterine tumor22
Developmental Stage
TissuesTPM*
adult44
embryoid body57
blastocyst32
fetus52
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue22
adrenal gland32.1
appendix13.4
bone marrow47.1
cerebral cortex55.3
colon41.8
duodenum18.6
esophagus56.1
gallbladder40.3
heart muscle54.1
kidney34.2
liver22
lung24.4
lymph node15.3
ovary74.6
pancreas20.3
placenta26.8
prostate37.3
salivary gland61.2
skin41.2
small intestine24.7
spleen13.3
stomach18.5
testis28.9
thyroid gland71.6
urinary bladder28.9
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(#176807, phenotype) Prostate cancerOMIM
2(*600020, gene) Max-interacting protein 1; MXI1OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2020 (C) Yonsei Proteome Research Center