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> Protein (NX_P51790)
Protein (NX_P51790)
Protein
Gene SymbolCLCN3 to neXtProt (NX_P51790)
DescriptionH(+)/Cl(-) exchange transporter 3
Chromosome4
Location4q33 (170533784 ~ 170644824) to Ensembl
Sequene Features : Isoforms 4, Variants 102, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of anion transmembrane transport
.chloride transmembrane transport
.transmembrane transport
  + 6 more...
.volume-sensitive chloride channel activity
.protein heterodimerization activity
.protein homodimerization activity
  + 5 more...
.phagocytic vesicle
.specific granule
.late endosome membrane
  + 16 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 102 3
2014-09-19protein level
4 76 3
2014-05-27protein level
4 76 3
2014-02-25protein level
3 72 3
2013-12-09protein level
3 60 3
2013-11-01protein level
3 56 3
2013-09-12protein level
3 56 3
2013-08-17protein level
3 56 3
2013-07-15protein level
3 35 3
2013-06-11protein level
3 35 3
2013-02-12protein level
3 13 9
2012-12-20protein level
2 12 6
2012-10-30protein level
2 15 6
2012-10-07protein level
2 15 3
2012-08-24protein level
2 14 3
2012-07-28protein level
2 14 3
2012-06-08protein level
2 21 3
2012-05-07protein level
2 12 3
2012-04-10protein level
2 12 3
2012-01-13protein level
2 11 3
2011-12-20protein level
2 11 3
2011-11-11protein level
2 11 3
2011-08-23protein level
2 11 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P51790-1
0 30 4 90907.014
NX_P51790-2
6 29 3 96669.9858
NX_P51790-4
1 29 4 88406.6997
NX_P51790-5
1 28 4 88723.342
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland60
bladder33
blood57
bone13
bone marrow123
brain104
cervix20
connective tissue26
ear248
embryonic tissue61
esophagus49
eye4
kidney9
lung2
mammary gland6
mouth15
placenta3
testis6
thymus25
trachea19
vascular19
Health State
TissuesTPM*
normal6
adrenal tumor79
bladder carcinoma113
breast (mammary gland) tumor64
cervical tumor28
chondrosarcoma36
colorectal tumor142
esophageal tumor57
germ cell tumor7
glioma9
head and neck tumor7
non-neoplasia10
Developmental Stage
TissuesTPM*
adult68
embryoid body85
blastocyst48
neonate32
fetus149
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue14.7
adrenal gland29.7
appendix19
bone marrow6.8
cerebral cortex51.8
colon41.8
duodenum25.9
esophagus42.1
gallbladder39.8
heart muscle25.9
kidney26.9
liver10.7
lung16.6
lymph node17.3
ovary19.4
pancreas17.7
placenta19.2
prostate29.5
salivary gland54.8
skin22.7
small intestine25.4
spleen12.5
stomach31.5
testis33.3
thyroid gland44.7
urinary bladder42.7
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600580, gene) Chloride channel 3; CLCN3OMIM


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