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> Protein (NX_P51959)
Protein (NX_P51959)
Protein
Gene SymbolCCNG1 to neXtProt (NX_P51959)
DescriptionCyclin-G1
Chromosome5
Location5q34 (162864575 ~ 162873157) to Ensembl
Sequene Features : Isoforms 2, Variants 36, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cell division
.negative regulation of apoptotic process
.cell growth
  + 6 more...
.N/A .perinuclear region of cytoplasm
.neuronal cell body
.dendrite
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 36 1
2014-09-19protein level
1 33 1
2014-05-27protein level
1 33 1
2014-02-25protein level
1 33 1
2013-12-09protein level
1 25 1
2013-11-01protein level
1 24 1
2013-09-12protein level
1 24 1
2013-08-17protein level
1 24 1
2013-07-15protein level
1 16 0
2013-06-11protein level
1 16 0
2013-02-12protein level
1 10 0
2012-12-20protein level
1 11 0
2012-10-30protein level
1 12 0
2012-10-07protein level
1 12 0
2012-08-24protein level
1 10 0
2012-07-28protein level
1 10 0
2012-06-08protein level
1 14 0
2012-05-07protein level
1 10 0
2012-04-10protein level
1 10 0
2012-01-13protein level
1 9 0
2011-12-20protein level
1 9 0
2011-11-11protein level
1 9 0
2011-08-23protein level
1 9 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P51959-1
7 7 0 34051.8416
NX_P51959-2
0 7 0 18756.9141
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-3905829,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
2 EBI-3905829,EBI-357849 TNIP1  
  .modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade
.negative regulation of ERK1 and ERK2 cascade
.positive regulation of inflammatory response
  + 9 more...
.mitogen-activated protein kinase binding .cytoplasm
.nucleus
.intracellular
3 EBI-3905829,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
4 EBI-3905829,EBI-2549423 HMBOX1  
  .positive regulation of transcription, DNA-templated
.negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.DNA binding .cytoplasm
.nucleoplasm
.nucleus
5 EBI-3905829,EBI-741724 SPERT  
  .N/A .N/A .cytoplasmic membrane-bounded vesicle
6 EBI-3905829,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
7 EBI-3905829,EBI-740322 RBPMS  
  .positive regulation of SMAD protein import into nucleus
.positive regulation of pathway-restricted SMAD protein phosphorylation
.RNA processing
  + 2 more...
.poly(A) RNA binding
.poly(A) binding
.transcription coactivator activity
.nucleotide binding
.cytoplasm
.nucleoplasm
8 EBI-3905829,EBI-741037 LZTS2  
  .negative regulation of protein localization to nucleus
.negative regulation of canonical Wnt signaling pathway
.spindle midzone assembly
  + 7 more...
.N/A .midbody
.microtubule
.centrosome
.cytoplasm
9 EBI-3905829,EBI-1105213 TFIP11  
  .biomineral tissue development
.RNA processing
.regulation of transcription, DNA-templated
  + 2 more...
.DNA binding .catalytic step 2 spliceosome
.U2-type post-mRNA release spliceosomal complex
.nuclear speck
  + 3 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland121
ascites75
bladder435
blood122
bone97
bone marrow328
brain110
cervix164
connective tissue80
ear124
embryonic tissue140
eye229
heart145
intestine150
kidney161
larynx42
liver199
lung89
lymph135
lymph node111
mammary gland112
mouth75
muscle94
nerve128
ovary59
pancreas14
parathyroid291
pharynx49
placenta120
prostate63
salivary gland98
skin170
spleen93
stomach62
testis87
thymus175
thyroid21
trachea115
umbilical cord72
uterus189
vascular367
Health State
TissuesTPM*
normal109
adrenal tumor237
bladder carcinoma170
breast (mammary gland) tumor139
cervical tumor231
chondrosarcoma48
colorectal tumor133
gastrointestinal tumor42
germ cell tumor284
glioma65
head and neck tumor22
kidney tumor87
leukemia116
liver tumor343
lung tumor97
lymphoma83
non-neoplasia62
ovarian tumor105
pancreatic tumor19
primitive neuroectodermal tumor of the CNS102
prostate cancer38
retinoblastoma366
skin tumor55
soft tissue/muscle tissue tumor151
uterine tumor188
Developmental Stage
TissuesTPM*
adult92
embryoid body128
blastocyst97
neonate675
fetus123
infant212
juvenile179
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue48.4
adrenal gland64.5
appendix36
bone marrow31.1
cerebral cortex19.5
colon85.2
duodenum134.2
esophagus55.7
gallbladder71.5
heart muscle44.6
kidney100.9
liver70.1
lung36.3
lymph node60
ovary113.9
pancreas35.8
placenta52.3
prostate76.5
salivary gland52.3
skin24.9
small intestine112.3
spleen36
stomach63.1
testis29.7
thyroid gland73.5
urinary bladder85.2
Tissues
TissuesExpression level
adrenal glandHigh
appendixHigh
bone marrowMedium
breastHigh
bronchusHigh
cerebellumMedium
cerebral cortexHigh
cervix, uterineMedium
colonHigh
duodenumHigh
endometrium 1Medium
endometrium 2Medium
epididymisHigh
esophagusMedium
fallopian tubeMedium
gallbladderHigh
hippocampusHigh
kidneyHigh
lateral ventricleHigh
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaHigh
ovaryMedium
pancreasHigh
parathyroid glandLow
placentaHigh
prostateMedium
rectumMedium
salivary glandHigh
seminal vesicleMedium
skeletal muscleHigh
skin 1Medium
small intestineHigh
smooth muscleHigh
soft tissue 1High
soft tissue 2High
spleenMedium
stomach 1High
stomach 2Medium
testisHigh
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*601578, gene) Cyclin g1; CCNG1OMIM


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