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> Protein (NX_P52179)
Protein (NX_P52179)
Protein
Gene SymbolMYOM1 to neXtProt (NX_P52179)
DescriptionMyomesin-1
Chromosome18
Location18p11.31 (3066805 ~ 3220106) to Ensembl
Sequene Features : Isoforms 2, Variants 250, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.activation of mitophagy in response to mitochondrial depolarization
.muscle contraction
.positive regulation of defense response to virus by host
.protein homodimerization activity
.identical protein binding
.structural constituent of muscle
.M band
.striated muscle myosin thick filament
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 250 1
2014-09-19protein level
2 202 1
2014-05-27protein level
2 202 1
2014-02-25protein level
2 202 1
2013-12-09protein level
2 135 1
2013-11-01protein level
2 134 1
2013-09-12protein level
2 134 1
2013-08-17protein level
2 134 1
2013-07-15protein level
2 84 1
2013-06-11protein level
2 84 1
2013-02-12protein level
2 39 2
2012-12-20protein level
2 34 2
2012-10-30protein level
2 67 2
2012-10-07protein level
2 67 1
2012-08-24protein level
2 51 1
2012-07-28protein level
2 51 1
2012-06-08protein level
2 65 1
2012-05-07protein level
2 65 1
2012-04-10protein level
2 65 1
2012-01-13protein level
2 35 1
2011-12-20protein level
2 35 1
2011-11-11protein level
2 35 1
2011-08-23protein level
2 35 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P52179-1
5 84 0 187508.9366
NX_P52179-2
1 84 0 177588.8612
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-5353249,EBI-2799016 DYSF  
  .vesicle fusion
.plasma membrane repair
.calcium-dependent phospholipid binding
.phospholipid binding
.calcium ion binding
.extracellular exosome
.sarcolemma
.cytoplasmic vesicle membrane
  + 8 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
blood8
bone27
brain5
eye33
heart279
kidney4
larynx42
liver29
muscle178
pancreas14
placenta17
prostate5
spleen18
stomach10
testis25
thyroid21
uterus8
Health State
TissuesTPM*
normal20
gastrointestinal tumor8
germ cell tumor11
head and neck tumor7
leukemia10
liver tumor10
pancreatic tumor19
Developmental Stage
TissuesTPM*
adult18
fetus25
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue13.5
adrenal gland5.5
appendix2.4
cerebral cortex3.1
colon3.6
duodenum1.5
esophagus13.6
gallbladder20.2
heart muscle274.9
kidney2.2
liver13.2
lung1.2
lymph node2.6
ovary2.5
pancreas4.1
placenta2
prostate18.9
salivary gland1.7
skin1.1
small intestine2.6
spleen1.1
stomach1.9
testis9.4
thyroid gland1.6
urinary bladder5.9
Tissues
TissuesExpression level
gallbladderLow
heart muscleMedium
skeletal muscleMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603508, gene) Myomesin 1; MYOM1OMIM


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