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> Protein (NX_P52742)
Protein (NX_P52742)
Protein
Gene SymbolZNF135 to neXtProt (NX_P52742)
DescriptionZinc finger protein 135
Chromosome19
Location19q13.43 (58570607 ~ 58597677) to Ensembl
Sequene Features : Isoforms 4, Variants 110, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of cell morphogenesis
.cytoskeleton organization
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
4 110 0
2014-09-19transcript level
4 85 0
2014-05-27transcript level
4 85 0
2014-02-25transcript level
4 84 0
2013-12-09transcript level
4 74 0
2013-11-01transcript level
4 69 0
2013-09-12transcript level
4 69 0
2013-08-17transcript level
4 69 0
2013-07-15transcript level
2 55 0
2013-06-11transcript level
2 55 0
2013-02-12transcript level
1 28 0
2012-12-20transcript level
1 33 0
2012-10-30transcript level
1 34 0
2012-10-07transcript level
1 34 0
2012-08-24transcript level
1 33 0
2012-07-28transcript level
1 32 0
2012-06-08transcript level
1 34 0
2012-05-07transcript level
1 30 0
2012-04-10transcript level
1 30 0
2012-01-13transcript level
1 14 0
2011-12-20transcript level
1 14 0
2011-11-11transcript level
1 14 0
2011-08-23transcript level
1 14 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P52742-1
0 31 10 75213.1617
NX_P52742-2
0 17 4 44793.0758
NX_P52742-3
0 32 10 76625.9393
NX_P52742-4
0 32 10 78100.7475
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bladder66
blood24
bone27
brain34
connective tissue13
ear62
embryonic tissue46
eye57
heart11
intestine12
kidney23
liver9
lung29
mammary gland39
mouth15
muscle75
nerve128
ovary59
pancreas32
parathyroid48
pharynx24
pituitary gland181
placenta45
prostate10
skin23
spleen37
stomach10
testis55
thymus62
thyroid64
uterus8
vascular19
Health State
TissuesTPM*
normal37
breast (mammary gland) tumor32
chondrosarcoma24
colorectal tumor17
gastrointestinal tumor8
germ cell tumor26
glioma18
head and neck tumor7
kidney tumor14
leukemia31
liver tumor10
lung tumor9
lymphoma27
ovarian tumor39
pancreatic tumor47
primitive neuroectodermal tumor of the CNS7
prostate cancer9
skin tumor15
soft tissue/muscle tissue tumor31
Developmental Stage
TissuesTPM*
adult33
embryoid body28
blastocyst65
fetus53
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.3
adrenal gland2.3
appendix1.8
cerebral cortex3.1
colon1.6
duodenum1.2
esophagus2.5
gallbladder4.2
heart muscle2.6
kidney2.9
lung2.9
lymph node1.9
ovary10.9
pancreas1.1
placenta2.8
prostate5.1
salivary gland1.7
skin3.9
small intestine1.4
spleen3.6
stomach1.8
testis6.7
thyroid gland6.7
urinary bladder3.2
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineHigh
colonHigh
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisMedium
esophagusMedium
fallopian tubeHigh
gallbladderMedium
heart muscleMedium
hippocampusMedium
kidneyMedium
lateral ventricleMedium
liverMedium
lungMedium
lymph nodeMedium
nasopharynxMedium
oral mucosaMedium
ovaryMedium
pancreasMedium
parathyroid glandMedium
placentaHigh
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleMedium
skin 1High
skin 2Medium
small intestineMedium
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Medium
spleenLow
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderHigh
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*604077, gene) Zinc finger protein 135; ZNF135OMIM


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