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> Protein (NX_P52744)
Protein (NX_P52744)
Protein
Gene SymbolZNF138 to neXtProt (NX_P52744)
DescriptionZinc finger protein 138
Chromosome7
Location7q11.21 (64254766 ~ 64294054) to Ensembl
Sequene Features : Isoforms 3, Variants 47, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01transcript level
3 47 0
2014-09-19transcript level
3 33 0
2014-05-27transcript level
3 33 0
2014-02-25transcript level
3 32 0
2013-12-09transcript level
3 24 0
2013-11-01transcript level
3 24 0
2013-09-12transcript level
3 24 0
2013-08-17transcript level
3 24 0
2013-07-15transcript level
2 17 0
2013-06-11transcript level
2 17 0
2013-02-12transcript level
2 8 0
2012-12-20transcript level
1 10 0
2012-10-30transcript level
1 10 0
2012-10-07transcript level
1 10 0
2012-08-24transcript level
1 10 0
2012-07-28transcript level
1 10 0
2012-06-08transcript level
1 12 0
2012-05-07transcript level
1 12 0
2012-04-10transcript level
1 12 0
2012-01-13transcript level
1 8 0
2011-12-20transcript level
1 8 0
2011-11-11transcript level
1 8 0
2011-08-23transcript level
1 8 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P52744-1
0 5 2 30571.3345
NX_P52744-2
1 7 2 34310.0985
NX_P52744-3
3 2 0 14587.3332
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10213071,EBI-741925 DHPS  
  .protein homotetramerization
.deoxyhypusine biosynthetic process from spermidine
.cellular protein metabolic process
  + 6 more...
.deoxyhypusine synthase activity .cytosol
2 EBI-10213071,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
3 EBI-10213071,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
4 EBI-10213071,EBI-725997 TRIM41  
  .protein ubiquitination .ligase activity
.zinc ion binding
.cytoplasm
.nucleolus
5 EBI-10213071,EBI-742740 ZBTB8A  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
6 EBI-10213071,EBI-724076 MDFI  
  .trophoblast giant cell differentiation
.embryonic skeletal system morphogenesis
.negative regulation of DNA binding
  + 6 more...
.N/A .cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites25
brain15
connective tissue20
embryonic tissue18
esophagus49
eye4
intestine8
kidney28
lung2
mammary gland6
mouth30
muscle18
nerve64
pancreas9
pituitary gland60
placenta14
prostate5
skin9
testis22
thymus50
trachea38
uterus17
vascular19
Health State
TissuesTPM*
normal11
chondrosarcoma12
colorectal tumor17
esophageal tumor57
gastrointestinal tumor8
germ cell tumor30
head and neck tumor14
kidney tumor29
non-neoplasia31
primitive neuroectodermal tumor of the CNS23
prostate cancer9
retinoblastoma21
skin tumor7
soft tissue/muscle tissue tumor15
uterine tumor33
Developmental Stage
TissuesTPM*
adult11
embryoid body14
blastocyst16
fetus19
infant42
juvenile17
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue3.6
adrenal gland8.3
appendix4.8
bone marrow2.6
cerebral cortex9.9
colon4.8
duodenum3.4
esophagus5.1
gallbladder4.7
heart muscle2.2
kidney5.9
liver3.2
lung3.4
lymph node9.3
ovary6.7
pancreas1.7
placenta3.2
prostate5.3
salivary gland4.5
skin9.6
small intestine3.8
spleen5.2
stomach4.9
testis7.7
thyroid gland8.1
urinary bladder6
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*604080, gene) Zinc finger protein 138; ZNF138OMIM


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