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> Protein (NX_P52799)
Protein (NX_P52799)
Protein
Gene SymbolEFNB2 to neXtProt (NX_P52799)
DescriptionEphrin-B2
Chromosome13
Location13q33.3 (107142079 ~ 107187462) to Ensembl
Sequene Features : Isoforms 1, Variants 35, PTMs 10 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of cardiac muscle cell differentiation
.regulation of chemotaxis
.ephrin receptor signaling pathway
  + 9 more...
.ephrin receptor binding .focal adhesion
.integral component of plasma membrane
.plasma membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 35 10
2014-09-19protein level
1 28 10
2014-05-27protein level
1 28 10
2014-02-25protein level
1 27 10
2013-12-09protein level
1 18 10
2013-11-01protein level
1 18 10
2013-09-12protein level
1 18 10
2013-08-17protein level
1 18 10
2013-07-15protein level
1 10 8
2013-06-11protein level
1 10 8
2013-02-12protein level
1 3 9
2012-12-20protein level
1 3 9
2012-10-30protein level
1 9 9
2012-10-07protein level
1 9 9
2012-08-24protein level
1 7 9
2012-07-28protein level
1 7 9
2012-06-08protein level
1 8 9
2012-05-07protein level
1 8 9
2012-04-10protein level
1 8 9
2012-01-13protein level
1 4 9
2011-12-20protein level
1 4 9
2011-11-11protein level
1 4 9
2011-08-23protein level
1 4 9
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P52799-1
13 0 1 36899.6882
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-7532268,EBI-713635 NCK2  
  .negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
.ephrin receptor signaling pathway
.vascular endothelial growth factor receptor signaling pathway
  + 16 more...
.receptor signaling complex scaffold activity
.cytoskeletal adaptor activity
.SH3/SH2 adaptor activity
.vesicle membrane
.cytosol
.endoplasmic reticulum
.cytoplasm
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
bladder33
blood8
bone97
brain30
connective tissue20
ear248
embryonic tissue93
eye38
heart122
intestine43
kidney47
liver53
lung23
lymph node33
mammary gland26
muscle18
ovary39
pancreas23
placenta56
prostate10
skin33
spleen37
stomach10
testis18
thymus12
thyroid64
uterus68
vascular77
Health State
TissuesTPM*
normal50
breast (mammary gland) tumor10
chondrosarcoma84
colorectal tumor53
gastrointestinal tumor8
germ cell tumor15
glioma37
head and neck tumor22
leukemia10
liver tumor62
lung tumor19
non-neoplasia41
ovarian tumor52
pancreatic tumor28
primitive neuroectodermal tumor of the CNS7
soft tissue/muscle tissue tumor7
uterine tumor66
Developmental Stage
TissuesTPM*
adult39
embryoid body171
blastocyst81
fetus62
infant297
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue14.8
adrenal gland6.2
appendix10
cerebral cortex11.5
colon32.2
duodenum16.5
esophagus14.4
gallbladder11.6
heart muscle12
kidney14
liver3.5
lung35.2
lymph node7.4
ovary3.7
pancreas2.1
placenta24.5
prostate15.6
salivary gland3.7
skin12.1
small intestine16.2
spleen11.9
stomach27.3
testis9
thyroid gland14.1
urinary bladder11.7
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowLow
breastLow
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineLow
colonMedium
duodenumMedium
endometrium 1Low
endometrium 2Medium
epididymisMedium
esophagusLow
fallopian tubeLow
gallbladderMedium
heart muscleMedium
hippocampusLow
kidneyMedium
lateral ventricleLow
liverMedium
lungMedium
lymph nodeLow
nasopharynxLow
oral mucosaLow
ovaryLow
pancreasLow
parathyroid glandLow
placentaMedium
prostateLow
rectumMedium
salivary glandLow
seminal vesicleMedium
skeletal muscleMedium
skin 1Medium
skin 2Medium
small intestineLow
soft tissue 1Low
soft tissue 2Low
spleenLow
stomach 1Medium
stomach 2Low
testisMedium
thyroid glandLow
tonsilLow
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600527, gene) Ephrin b2; EFNB2OMIM


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