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> Protein (NX_P53992)
Protein (NX_P53992)
Protein
Gene SymbolSEC24C to neXtProt (NX_P53992)
DescriptionProtein transport protein Sec24C
Chromosome10
Location10q22.2 (75504120 ~ 75531919) to Ensembl
Sequene Features : Isoforms 2, Variants 118, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.membrane organization
.COPII vesicle coating
.small molecule metabolic process
  + 7 more...
.zinc ion binding .perinuclear region of cytoplasm
.COPII vesicle coat
.ER to Golgi transport vesicle membrane
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 118 4
2014-09-19protein level
1 99 4
2014-05-27protein level
1 99 4
2014-02-25protein level
1 98 4
2013-12-09protein level
1 74 4
2013-11-01protein level
1 68 4
2013-09-12protein level
1 68 4
2013-08-17protein level
1 68 4
2013-07-15protein level
1 50 3
2013-06-11protein level
1 50 3
2013-02-12protein level
1 25 3
2012-12-20protein level
1 24 3
2012-10-30protein level
1 29 3
2012-10-07protein level
1 29 3
2012-08-24protein level
1 29 3
2012-07-28protein level
1 29 3
2012-06-08protein level
1 29 3
2012-05-07protein level
1 23 3
2012-04-10protein level
1 23 3
2012-01-13protein level
1 14 3
2011-12-20protein level
1 14 3
2011-11-11protein level
1 14 3
2011-08-23protein level
1 14 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P53992-1
28 13 1 118248.8183
NX_P53992-2
0 13 0 38156.3851
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-81134,EBI-346356 WIPF1  
  .response to other organism
.innate immune response
.Fc-gamma receptor signaling pathway involved in phagocytosis
  + 4 more...
.profilin binding
.actin binding
.cytoplasmic membrane-bounded vesicle
.actin cytoskeleton
.actin filament
  + 2 more...
2 EBI-81134,EBI-1757866 MOS  
  .negative regulation of metaphase/anaphase transition of meiotic cell cycle
.establishment of meiotic spindle orientation
.protein autophosphorylation
  + 6 more...
.ATP binding
.MAP kinase kinase kinase activity
.protein serine/threonine kinase activity
.cytoplasm
3 EBI-81134,EBI-81088 SEC23A  
  .membrane organization
.COPII vesicle coating
.small molecule metabolic process
  + 8 more...
.zinc ion binding .perinuclear region of cytoplasm
.smooth endoplasmic reticulum membrane
.COPII vesicle coat
  + 5 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites25
blood179
bone111
bone marrow41
brain46
cervix61
connective tissue80
embryonic tissue140
esophagus49
eye114
heart55
intestine206
kidney56
larynx298
liver68
lung80
lymph135
lymph node77
mammary gland59
mouth136
muscle112
nerve128
ovary68
pancreas74
parathyroid145
pharynx49
pituitary gland121
placenta81
prostate137
skin109
spleen37
stomach83
testis66
thymus87
thyroid128
trachea57
umbilical cord145
uterus73
vascular96
Health State
TissuesTPM*
normal69
bladder carcinoma56
breast (mammary gland) tumor64
cervical tumor28
chondrosarcoma229
colorectal tumor328
esophageal tumor57
gastrointestinal tumor42
germ cell tumor49
glioma102
head and neck tumor119
kidney tumor101
leukemia254
liver tumor62
lung tumor126
lymphoma124
non-neoplasia51
ovarian tumor78
pancreatic tumor57
primitive neuroectodermal tumor of the CNS70
prostate cancer211
retinoblastoma64
skin tumor159
soft tissue/muscle tissue tumor79
uterine tumor99
Developmental Stage
TissuesTPM*
adult122
embryoid body185
blastocyst211
fetus70
juvenile107
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue28.1
adrenal gland39.8
appendix38
bone marrow26.7
cerebral cortex26.1
colon33.2
duodenum30.5
esophagus52.3
gallbladder31.8
heart muscle26.3
kidney27.7
liver22.7
lung38.7
lymph node46.3
ovary33.8
pancreas15.3
placenta43.7
prostate37.4
salivary gland31.1
skin38
small intestine34.7
spleen37.9
stomach31.4
testis37.1
thyroid gland47
urinary bladder38.2
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineMedium
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Low
epididymisMedium
esophagusMedium
fallopian tubeMedium
gallbladderMedium
heart muscleMedium
hippocampusMedium
kidneyHigh
lateral ventricleMedium
liverMedium
lungMedium
lymph nodeLow
nasopharynxMedium
oral mucosaMedium
ovaryLow
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateMedium
rectumMedium
salivary glandMedium
seminal vesicleMedium
skeletal muscleLow
skin 1Medium
skin 2Medium
small intestineMedium
smooth muscleLow
soft tissue 1Medium
soft tissue 2Medium
spleenLow
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandMedium
tonsilMedium
urinary bladderMedium
vaginaMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*607185, gene) Sec24-related gene family, member c; SEC24COMIM


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