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> Protein (NX_P54762)
Protein (NX_P54762)
Protein
Gene SymbolEPHB1 to neXtProt (NX_P54762)
DescriptionEphrin type-B receptor 1
Chromosome3
Location3q22.2 (134316643 ~ 134979309) to Ensembl
Sequene Features : Isoforms 3, Variants 262, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of neuron death
.regulation of ERK1 and ERK2 cascade
.neural precursor cell proliferation
  + 17 more...
.axon guidance receptor activity
.ATP binding
.transmembrane-ephrin receptor activity
.extracellular exosome
.membrane raft
.early endosome membrane
  + 6 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
3 262 4
2014-09-19protein level
1 193 4
2014-05-27protein level
1 193 5
2014-02-25protein level
1 193 5
2013-12-09protein level
1 171 5
2013-11-01protein level
1 170 5
2013-09-12protein level
1 170 5
2013-08-17protein level
1 170 5
2013-07-15protein level
1 109 5
2013-06-11protein level
1 109 5
2013-02-12protein level
1 47 6
2012-12-20protein level
1 48 6
2012-10-30protein level
1 53 6
2012-10-07protein level
1 53 6
2012-08-24protein level
1 48 6
2012-07-28protein level
1 48 6
2012-06-08protein level
1 66 6
2012-05-07protein level
1 34 6
2012-04-10protein level
1 34 6
2012-01-13protein level
1 34 6
2011-12-20protein level
1 34 6
2011-11-11protein level
1 34 5
2011-08-23protein level
1 30 5
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P54762-1
14 27 7 109814.228
NX_P54762-5
1 20 6 61361.9549
NX_P54762-6
5 7 0 26888.4724
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-80252,EBI-401755 GRB2  
  .positive regulation of reactive oxygen species metabolic process
.cellular response to ionizing radiation
.branching involved in labyrinthine layer morphogenesis
  + 25 more...
.ephrin receptor binding
.poly(A) RNA binding
.insulin receptor substrate binding
  + 6 more...
.Grb2-EGFR complex
.extracellular exosome
.vesicle membrane
  + 10 more...
2 EBI-80252,EBI-80275 GRB10  
  .insulin-like growth factor receptor signaling pathway
.negative regulation of insulin receptor signaling pathway
.negative regulation of glucose import
  + 7 more...
.insulin receptor binding
.SH3/SH2 adaptor activity
.plasma membrane
.cytosol
.cytoplasm
3 EBI-80252,EBI-970191 GRB7  
  .leukocyte migration
.stress granule assembly
.positive regulation of cell migration
  + 4 more...
.identical protein binding
.phosphatidylinositol binding
.protein kinase binding
  + 2 more...
.cell projection
.cytoplasmic stress granule
.focal adhesion
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain73
embryonic tissue9
eye19
intestine4
lung11
mammary gland46
mouth45
muscle18
ovary19
prostate5
testis45
trachea19
vascular19
Health State
TissuesTPM*
normal28
colorectal tumor8
germ cell tumor64
glioma55
head and neck tumor22
ovarian tumor26
Developmental Stage
TissuesTPM*
adult11
blastocyst32
fetus64
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue1.4
adrenal gland1.6
appendix1.6
bone marrow1.1
cerebral cortex12.6
duodenum1
esophagus1.9
gallbladder1.7
kidney1.1
lymph node1.7
prostate3.6
salivary gland1.3
skin4.5
spleen3.3
testis7.4
thyroid gland6.9
urinary bladder1.7
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*600600, gene) Ephrin receptor ephb1; EPHB1OMIM


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