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> Protein (NX_P54920)
Protein (NX_P54920)
Protein
Gene SymbolNAPA to neXtProt (NX_P54920)
DescriptionAlpha-soluble NSF attachment protein
Chromosome19
Location19q13.32 (47990894 ~ 48018497) to Ensembl
Sequene Features : Isoforms 1, Variants 38, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.membrane fusion
.membrane organization
.apical protein localization
  + 8 more...
.syntaxin binding
.soluble NSF attachment protein activity
.extracellular exosome
.synaptobrevin 2-SNAP-25-syntaxin-1a complex
.SNARE complex
  + 3 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 38 4
2014-09-19protein level
1 28 4
2014-05-27protein level
1 28 5
2014-02-25protein level
1 28 5
2013-12-09protein level
1 24 5
2013-11-01protein level
1 23 4
2013-09-12protein level
1 23 3
2013-08-17protein level
1 23 3
2013-07-15protein level
1 13 1
2013-06-11protein level
1 13 1
2013-02-12protein level
1 7 0
2012-12-20protein level
1 7 0
2012-10-30protein level
1 8 0
2012-10-07protein level
1 8 0
2012-08-24protein level
1 6 0
2012-07-28protein level
1 6 0
2012-06-08protein level
1 7 0
2012-05-07protein level
1 7 0
2012-04-10protein level
1 7 0
2012-01-13protein level
1 1 0
2011-12-20protein level
1 1 0
2011-11-11protein level
1 1 0
2011-08-23protein level
1 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P54920-1
14 0 3 33211.1874
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-749652,EBI-745000 SNAP23  
  .membrane fusion
.membrane organization
.synaptic vesicle fusion to presynaptic membrane
  + 5 more...
.syntaxin binding
.SNAP receptor activity
.extracellular exosome
.synapse
.neuron projection
  + 8 more...
2 EBI-749652,EBI-712251 NSF  
  .Golgi vesicle docking
.ATP metabolic process
.positive regulation of protein catabolic process
  + 10 more...
.metal ion binding
.ATPase activity, coupled
.protein complex binding
  + 6 more...
.extracellular exosome
.dendritic shaft
.postsynaptic density
  + 5 more...
3 EBI-749652,EBI-744942 STX4  
  .positive regulation of protein localization to cell surface
.positive regulation of protein localization to plasma membrane
.regulation of extrinsic apoptotic signaling pathway via death domain receptors
  + 21 more...
.sphingomyelin phosphodiesterase activator activity
.SNAP receptor activity
.SNARE binding
.extracellular exosome
.perinuclear region of cytoplasm
.synapse
  + 19 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue77
adrenal gland303
ascites301
blood163
bone153
bone marrow41
brain291
cervix288
connective tissue93
embryonic tissue136
esophagus248
eye172
heart78
intestine202
kidney118
larynx42
liver107
lung176
lymph45
lymph node66
mammary gland79
mouth90
muscle131
nerve128
ovary108
pancreas360
parathyroid48
placenta7
prostate15
spleen18
testis2
Health State
TissuesTPM*
normal183
adrenal tumor158
bladder carcinoma56
breast (mammary gland) tumor64
cervical tumor231
chondrosarcoma60
colorectal tumor124
esophageal tumor173
gastrointestinal tumor160
germ cell tumor45
glioma139
head and neck tumor141
kidney tumor116
leukemia95
liver tumor145
lung tumor243
lymphoma193
non-neoplasia289
ovarian tumor78
pancreatic tumor657
primitive neuroectodermal tumor of the CNS196
prostate cancer105
retinoblastoma279
skin tumor143
soft tissue/muscle tissue tumor63
uterine tumor144
Developmental Stage
TissuesTPM*
adult136
embryoid body85
blastocyst146
neonate32
fetus107
infant297
juvenile161
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue60.7
adrenal gland106.5
appendix58.7
bone marrow87.6
cerebral cortex84.1
colon60.4
duodenum57.1
esophagus103.4
gallbladder75.2
heart muscle86
kidney71.1
liver58.2
lung69.9
lymph node60.9
ovary52.5
pancreas47.1
placenta58.2
prostate100
salivary gland91.3
skin94.4
small intestine57.6
spleen63
stomach62.3
testis85.2
thyroid gland89.3
urinary bladder83.5
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603215, gene) N-ethylmaleimide-sensitive factor attachment protein, alpha; NAPAOMIM


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