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> Protein (NX_P55064)
Protein (NX_P55064)
Protein
Gene SymbolAQP5 to neXtProt (NX_P55064)
DescriptionAquaporin-5
Chromosome12
Location12q13.12 (50355653 ~ 50359464) to Ensembl
Sequene Features : Isoforms 1, Variants 37, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.transmembrane transport
.camera-type eye morphogenesis
.saliva secretion
  + 8 more...
.glycerol channel activity
.water channel activity
.extracellular exosome
.apical plasma membrane
.basal plasma membrane
  + 4 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 37 2
2014-09-19protein level
1 34 2
2014-05-27protein level
1 34 2
2014-02-25protein level
1 34 2
2013-12-09protein level
1 24 2
2013-11-01protein level
1 22 2
2013-09-12protein level
1 22 2
2013-08-17protein level
1 22 2
2013-07-15protein level
1 15 2
2013-06-11protein level
1 15 2
2013-02-12protein level
1 10 2
2012-12-20protein level
1 10 2
2012-10-30protein level
1 11 2
2012-10-07protein level
1 11 2
2012-08-24protein level
1 11 2
2012-07-28protein level
1 11 2
2012-06-08protein level
1 11 2
2012-05-07protein level
1 10 2
2012-04-10protein level
1 10 2
2012-01-13protein level
1 3 2
2011-12-20protein level
1 3 2
2011-11-11protein level
1 3 2
2011-08-23protein level
1 3 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P55064-1
9 0 0 28274.0243
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-746103,EBI-948001 KRT31  
  .epidermis development .structural constituent of cytoskeleton .extracellular exosome
.intermediate filament
.extracellular space
2 EBI-746103,EBI-10171697 KRT40  
  .N/A .structural molecule activity .intermediate filament
3 EBI-746103,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
4 EBI-746103,EBI-724076 MDFI  
  .trophoblast giant cell differentiation
.embryonic skeletal system morphogenesis
.negative regulation of DNA binding
  + 6 more...
.N/A .cytoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
brain20
connective tissue93
eye119
intestine12
larynx42
lung11
ovary68
placenta7
skin18
stomach167
testis144
uterus30
Health State
TissuesTPM*
normal21
adrenal tumor79
gastrointestinal tumor92
germ cell tumor11
glioma9
non-neoplasia31
ovarian tumor91
soft tissue/muscle tissue tumor111
uterine tumor77
Developmental Stage
TissuesTPM*
adult46
fetus14
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
duodenum11.8
esophagus6.8
gallbladder3.4
kidney1.3
lung10.6
prostate1.8
salivary gland393.4
stomach53.1
testis109.7
thyroid gland1.5
Tissues
TissuesExpression level
breastLow
bronchusMedium
colonLow
duodenumLow
endometrium 1Medium
fallopian tubeLow
nasopharynxMedium
pancreasMedium
rectumLow
salivary glandHigh
small intestineLow
stomach 1Low
stomach 2Low
testisMedium
tonsilLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(%600231, phenotype) Palmoplantar keratoderma, bothnian type; PPKBOMIM
2(*600442, gene) Aquaporin 5; AQP5OMIM


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