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> Protein (NX_P55087)
Protein (NX_P55087)
Protein
Gene SymbolAQP4 to neXtProt (NX_P55087)
DescriptionAquaporin-4
Chromosome18
Location18q11.2 (24432002 ~ 24445782) to Ensembl
Sequene Features : Isoforms 2, Variants 45, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to estradiol stimulus
.cellular response to interferon-gamma
.renal water absorption
  + 15 more...
.porin activity
.glycerol channel activity
.water channel activity
.water transmembrane transporter activity
.protein complex
.T-tubule
.basolateral plasma membrane
  + 5 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 45 6
2014-09-19protein level
2 38 6
2014-05-27protein level
2 38 6
2014-02-25protein level
2 38 6
2013-12-09protein level
2 26 6
2013-11-01protein level
2 25 6
2013-09-12protein level
2 25 6
2013-08-17protein level
2 25 6
2013-07-15protein level
2 17 6
2013-06-11protein level
2 17 6
2013-02-12protein level
2 10 12
2012-12-20protein level
2 9 12
2012-10-30protein level
2 10 12
2012-10-07protein level
2 10 6
2012-08-24protein level
2 8 6
2012-07-28protein level
2 8 6
2012-06-08protein level
2 11 6
2012-05-07protein level
2 11 6
2012-04-10protein level
2 11 6
2012-01-13protein level
2 10 6
2011-12-20protein level
2 10 6
2011-11-11protein level
2 10 6
2011-08-23protein level
2 10 6
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P55087-1
2 8 0 34806.8584
NX_P55087-2
0 8 0 32278.6347
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
brain176
connective tissue33
embryonic tissue4
eye33
intestine4
kidney4
larynx42
lung35
muscle9
nerve64
pituitary gland60
prostate5
thyroid42
vascular58
Health State
TissuesTPM*
normal57
chondrosarcoma60
colorectal tumor8
germ cell tumor26
glioma111
head and neck tumor22
kidney tumor14
lung tumor19
non-neoplasia124
Developmental Stage
TissuesTPM*
adult34
embryoid body14
fetus26
infant42
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
cerebral cortex335.5
esophagus1
heart muscle2.1
kidney2
liver1.1
lung114.2
ovary2.7
stomach8.7
thyroid gland14.8
Tissues
TissuesExpression level
cerebral cortexHigh
lateral ventricleMedium
lungMedium
stomach 1High
stomach 2Medium
thyroid glandMedium
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600308, gene) Aquaporin 4; AQP4OMIM


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