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> Protein (NX_P57086)
Protein (NX_P57086)
Protein
Gene SymbolSCAND1 to neXtProt (NX_P57086)
DescriptionSCAN domain-containing protein 1
Chromosome20
Location20q11.23 (34541539 ~ 34547394) to Ensembl
Sequene Features : Isoforms 1, Variants 8, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.identical protein binding
.transcription coactivator activity
.sequence-specific DNA binding transcription factor activity
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 8 1
2014-09-19protein level
1 7 1
2014-05-27protein level
1 7 1
2014-02-25protein level
1 7 1
2013-12-09protein level
1 2 1
2013-11-01protein level
1 2 1
2013-09-12protein level
1 2 1
2013-08-17protein level
1 2 1
2013-07-15protein level
1 0 0
2013-06-11protein level
1 0 0
2013-02-12protein level
1 0 0
2012-12-20protein level
1 0 0
2012-10-30protein level
1 0 0
2012-10-07protein level
1 0 0
2012-08-24protein level
1 0 0
2012-07-28protein level
1 0 0
2012-06-08protein level
1 4 0
2012-05-07protein level
1 4 0
2012-04-10protein level
1 4 0
2012-01-13protein level
1 4 0
2011-12-20protein level
1 4 0
2011-11-11protein level
1 4 0
2011-08-23transcript level
1 4 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P57086-1
8 0 0 19069.9657
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-745846,EBI-10215956 ZNF449  
  .transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
2 EBI-745846,EBI-302345 PNMA1  
  .positive regulation of apoptotic process
.inflammatory response to antigenic stimulus
.N/A .focal adhesion
.cytoplasm
.nucleolus
3 EBI-745846,EBI-2818641 ZKSCAN4  
  .transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
4 EBI-745846,EBI-10290053 PGBD1  
  .N/A .scavenger receptor activity
.sequence-specific DNA binding transcription factor activity
.membrane
.nucleus
5 EBI-745846,EBI-739467 GORASP2  
  .organelle organization
.mitotic cell cycle
.N/A .membrane
.Golgi apparatus
.Golgi membrane
6 EBI-745846,EBI-743851 ZKSCAN7  
  .transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
blood8
bone111
brain59
connective tissue6
embryonic tissue28
esophagus49
eye43
heart55
intestine60
kidney104
liver19
lung44
lymph45
lymph node256
mammary gland39
muscle28
ovary108
pancreas89
placenta52
prostate84
skin156
stomach10
testis50
tonsil58
uterus68
vascular19
Health State
TissuesTPM*
normal47
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor21
chondrosarcoma48
colorectal tumor26
esophageal tumor57
gastrointestinal tumor75
germ cell tumor72
glioma261
kidney tumor29
leukemia42
liver tumor41
lung tumor29
lymphoma55
non-neoplasia62
ovarian tumor91
pancreatic tumor57
primitive neuroectodermal tumor of the CNS118
prostate cancer115
skin tumor175
soft tissue/muscle tissue tumor55
uterine tumor55
Developmental Stage
TissuesTPM*
adult46
embryoid body14
blastocyst32
fetus48
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue19
adrenal gland9.9
appendix9.3
bone marrow15.3
cerebral cortex9.2
colon14.7
duodenum13.3
esophagus1.7
gallbladder3.5
heart muscle4.2
kidney18.7
liver7.6
lung9.9
lymph node6.5
ovary5.5
pancreas5.5
placenta5.9
prostate16.2
salivary gland11.5
skin6.8
small intestine11.1
spleen17
stomach19.9
testis10.2
thyroid gland2.6
urinary bladder3.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*610416, gene) Scan domain-containing 1; SCAND1OMIM


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