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	> Protein (NX_P57103) Protein (NX_P57103) Protein Gene Symbol SLC8A3 to neXtProt (NX_P57103) Description Sodium/calcium exchanger 3 Chromosome 14 Location 14q24.2 (70510934 ~ 70655787) to Ensembl Sequene Features : Isoforms 7, Variants 202, PTMs 2 to neXtProt Sequence Features Gene Ontologies GO: Biological Process GO: Mulecular Function GO: Cellular Component .calcium ion import into cell .calcium ion export from cell .cellular response to cAMP   + 7 more... .calcium:sodium antiporter activity .dendritic spine .neuronal cell body .sarcolemma   + 4 more... Proteomic Evidences Release Protein Evidence Pr Ab Isoforms Variants PTMs 2015-01-01 protein level 7 202 2 2014-09-19 protein level 7 137 2 2014-05-27 protein level 7 132 2 2014-02-25 protein level 7 130 2 2013-12-09 protein level 7 107 2 2013-11-01 protein level 7 100 2 2013-09-12 protein level 7 100 2 2013-08-17 protein level 7 100 2 2013-07-15 transcript level 7 68 2 2013-06-11 transcript level 7 68 2 2013-02-12 transcript level 7 37 11 2012-12-20 transcript level 7 37 11 2012-10-30 transcript level 6 38 9 2012-10-07 transcript level 6 38 2 2012-08-24 transcript level 6 22 2 2012-07-28 transcript level 6 22 2 2012-06-08 transcript level 6 22 2 2012-05-07 transcript level 5 22 2 2012-04-10 transcript level 3 22 2 2012-01-13 transcript level 3 11 2 2011-12-20 transcript level 3 11 2 2011-11-11 transcript level 3 11 2 2011-08-23 transcript level 3 11 2 Protein Isoforms Isoform Ac   U G S Mw (Da) NX_P57103-1 1 31 2 102942.8955 NX_P57103-2 0 32 2 102348.5232 NX_P57103-3 1 20 0 68902.4325 NX_P57103-4 0 8 2 31121.7173 NX_P57103-5 0 10 2 32723.5321 NX_P57103-6 1 31 2 102627.7533 NX_P57103-7 4 29 2 102736.7263 : Uniquely mapped peptide : Gene-specific peptide : Shared peptide EST expression level of Protein Coding Gene (ref. NCBI UniGene EST) Body Sites Tissues TPM* blood 8 bone 13 brain 34 ear 62 eye 38 muscle 28 Health State Tissues TPM* normal 14 germ cell tumor 3 glioma 18 non-neoplasia 10 primitive neuroectodermal tumor of the CNS 86 Developmental Stage Tissues TPM* adult 9 fetus 28 TPM*: Transcripts per million; transcript expression level measured by expression sequence tags. Expression level of Protein (ref. Human Protein Atlas) RNA-Seq. Tissues FPKM adrenal gland 1.4 cerebral cortex 10.3 Cancer Tumor Number of patients and Staining levels breast cancer carcinoid cervical cancer colorectal cancer endometrial cancer glioma head and neck cancer liver cancer lung cancer lymphoma melanoma ovarian cancer pancreatic cancer prostate cancer renal cancer skin cancer stomach cancer testis cancer thyroid cancer urothelial cancer RNA-seq colour codes Highly expressed RNAs (FPKM >50) Moderately expressed RNAs (50> FPKM >10) Lower expressed RNAs (10> FPKM >1) The lowest expressed RNAs (FPKM value of 0 or 1) Staining level colour codes Highly expressed protein Moderately expressed protein Lower expressed protein Not Detected Disease No. Disease Description Ref. 1 (*607991, gene) Solute carrier family 8 (sodium-calcium exchanger), member 3; SLC8A3 OMIM

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