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> Protein (NX_P59998)
Protein (NX_P59998)
Protein
Gene SymbolARPC4 to neXtProt (NX_P59998)
DescriptionActin-related protein 2/3 complex subunit 4
Chromosome3
Location3p25.3 (9834179 ~ 9849410) to Ensembl
Sequene Features : Isoforms 4, Variants 8, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.ephrin receptor signaling pathway
.innate immune response
.actin nucleation
  + 5 more...
.enzyme binding
.structural constituent of cytoskeleton
.extracellular exosome
.cell projection
.Arp2/3 protein complex
.cytosol
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 8 2
2014-09-19protein level
4 5 2
2014-05-27protein level
4 5 2
2014-02-25protein level
4 5 2
2013-12-09protein level
4 3 2
2013-11-01protein level
4 3 1
2013-09-12protein level
4 3 1
2013-08-17protein level
4 3 1
2013-07-15protein level
3 1 1
2013-06-11protein level
3 1 1
2013-02-12protein level
1 0 3
2012-12-20protein level
1 0 3
2012-10-30protein level
1 0 3
2012-10-07protein level
1 0 3
2012-08-24protein level
1 0 3
2012-07-28protein level
1 0 3
2012-06-08protein level
1 1 3
2012-05-07protein level
1 2 3
2012-04-10protein level
1 2 3
2012-01-13protein level
1 2 3
2011-12-20protein level
1 2 3
2011-11-11protein level
1 2 3
2011-08-23protein level
1 2 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P59998-1
0 9 0 19654.2471
NX_P59998-2
0 6 27 71672.6535
NX_P59998-3
1 8 0 21574.1477
NX_P59998-4
0 4 0 9545.8222
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-351872,EBI-10171633 PNMA5  
  .positive regulation of apoptotic process .identical protein binding .N/A
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
adrenal gland30
ascites25
bladder33
blood212
bone181
bone marrow143
brain81
cervix268
connective tissue53
embryonic tissue159
esophagus248
eye81
heart55
intestine168
kidney56
liver63
lung65
lymph45
lymph node55
mammary gland72
mouth15
muscle28
nerve128
ovary68
pancreas32
pituitary gland60
placenta116
prostate174
salivary gland98
skin123
spleen93
stomach177
testis29
thymus150
thyroid42
tonsil176
trachea77
umbilical cord72
uterus90
vascular96
Health State
TissuesTPM*
normal81
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor64
cervical tumor231
chondrosarcoma132
colorectal tumor275
esophageal tumor231
gastrointestinal tumor101
germ cell tumor79
glioma130
head and neck tumor37
kidney tumor58
leukemia190
liver tumor104
lung tumor68
lymphoma152
non-neoplasia51
ovarian tumor39
pancreatic tumor66
primitive neuroectodermal tumor of the CNS196
prostate cancer288
retinoblastoma64
skin tumor183
soft tissue/muscle tissue tumor79
uterine tumor55
Developmental Stage
TissuesTPM*
adult99
embryoid body200
blastocyst130
neonate32
fetus68
infant42
juvenile125
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue98.6
adrenal gland93.2
appendix153.6
bone marrow109.4
cerebral cortex89.5
colon139.1
duodenum107.6
esophagus115.2
gallbladder92.6
heart muscle57
kidney94.1
liver56.9
lung99.2
lymph node193.1
ovary74.2
pancreas34
placenta87.8
prostate70.9
salivary gland59.2
skin74.4
small intestine105.3
spleen130.5
stomach92
testis50.5
thyroid gland92.7
urinary bladder135.4
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Disease
No.Disease DescriptionRef.
1(*604226, gene) Actin-related protein 2/3 complex, subunit 4; ARPC4OMIM


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