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> Protein (NX_P60409)
Protein (NX_P60409)
Protein
Gene SymbolKRTAP10-7 to neXtProt (NX_P60409)
DescriptionKeratin-associated protein 10-7
Chromosome21
Location21q22.3 (46020497 ~ 46022091) to Ensembl
Sequene Features : Isoforms 2, Variants 65, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .identical protein binding .keratin filament
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 65 0
2014-09-19protein level
2 44 0
2014-05-27transcript level
2 44 0
2014-02-25transcript level
2 44 0
2013-12-09transcript level
2 29 0
2013-11-01transcript level
2 29 0
2013-09-12transcript level
2 29 0
2013-08-17transcript level
2 29 0
2013-07-15transcript level
2 18 0
2013-06-11transcript level
2 18 0
2013-02-12transcript level
2 17 0
2012-12-20transcript level
2 16 0
2012-10-30transcript level
2 20 0
2012-10-07transcript level
2 20 0
2012-08-24transcript level
2 18 0
2012-07-28transcript level
2 18 0
2012-06-08transcript level
2 20 0
2012-05-07transcript level
2 17 0
2012-04-10transcript level
2 17 0
2012-01-13transcript level
2 17 0
2011-12-20transcript level
2 17 0
2011-11-11transcript level
2 17 0
2011-08-23transcript level
2 17 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P60409-1
0 2 2 37786.4354
NX_P60409-2
0 2 2 37325.2962
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10172290,EBI-10173019 ZNF320  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
2 EBI-10172290,EBI-727004 SDCBP  
  .positive regulation of extracellular exosome assembly
.positive regulation of exosomal secretion
.ephrin receptor signaling pathway
  + 9 more...
.protein N-terminus binding
.protein heterodimerization activity
.syndecan binding
  + 4 more...
.blood microparticle
.extracellular exosome
.melanosome
  + 12 more...
3 EBI-10172290,EBI-524257 TOR1A  
  .regulation of protein localization to cell surface
.positive regulation of synaptic vesicle endocytosis
.chaperone-mediated protein transport
  + 16 more...
.unfolded protein binding
.kinesin binding
.ATPase activity
  + 2 more...
.extracellular exosome
.intracellular membrane-bounded organelle
.extrinsic component of endoplasmic reticulum membrane
  + 12 more...
4 EBI-10172290,EBI-744471 ZBTB24  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.hematopoietic progenitor cell differentiation
.metal ion binding
.DNA binding
.nucleus
5 EBI-10172290,EBI-347522 ZNHIT1  
  .negative regulation of G0 to G1 transition
.histone exchange
.regulation of T cell proliferation
  + 2 more...
.metal ion binding
.histone deacetylase binding
.nucleosome binding
.nucleus
.Swr1 complex
6 EBI-10172290,EBI-349968 SUV39H1  
  .cellular response to hypoxia
.rhythmic process
.negative regulation of transcription, DNA-templated
  + 15 more...
.protein N-terminus binding
.histone methyltransferase activity (H3-K9 specific)
.histone methyltransferase activity
  + 5 more...
.rDNA heterochromatin
.chromatin silencing complex
.nucleoplasm
  + 5 more...
7 EBI-10172290,EBI-3866665 SPRY1  
  .negative regulation of ERK1 and ERK2 cascade
.bud elongation involved in lung branching
.negative regulation of neurotrophin TRK receptor signaling pathway
  + 10 more...
.N/A .plasma membrane
.cytosol
8 EBI-10172290,EBI-1053424 PRKAB2  
  .membrane organization
.regulation of protein kinase activity
.small molecule metabolic process
  + 13 more...
.identical protein binding .AMP-activated protein kinase complex
.cytosol
.nucleoplasm
9 EBI-10172290,EBI-947402 MAPKBP1  
  .N/A .N/A .N/A
10 EBI-10172290,EBI-5357290 TULP3  
  .negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning
.ganglion development
.smoothened signaling pathway involved in dorsal/ventral neural tube patterning
  + 14 more...
.phosphatidylinositol binding
.protein complex binding
.enzyme binding
.phosphatidylinositol-4,5-bisphosphate binding
.ciliary base
.primary cilium
.axoneme
  + 5 more...
11 EBI-10172290,EBI-718707 LRCH4  
  .nervous system development .N/A .PML body
12 EBI-10172290,EBI-749694 E2F6  
  .transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.regulation of transcription involved in G1/S transition of mitotic cell cycle
.transcription corepressor activity
.sequence-specific DNA binding transcription factor activity
.DNA binding
.MLL1 complex
.transcription factor complex
.nucleus
13 EBI-10172290,EBI-748664 HSBP1  
  .regulation of cellular response to heat
.endodermal cell differentiation
.cellular response to heat
  + 2 more...
.transcription corepressor activity .cytoskeleton
.nucleoplasm
.nucleus
14 EBI-10172290,EBI-749295 STK16  
  .cellular response to transforming growth factor beta stimulus
.protein autophosphorylation
.regulation of signal transduction
.ATP binding
.non-membrane spanning protein tyrosine kinase activity
.protein serine/threonine kinase activity
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.perinuclear region of cytoplasm
.membrane
.Golgi-associated vesicle
.cytoplasm
15 EBI-10172290,EBI-2513774 FARS2  
  .gene expression
.tRNA processing
.phenylalanyl-tRNA aminoacylation
.tRNA aminoacylation for protein translation
.ATP binding
.phenylalanine-tRNA ligase activity
.magnesium ion binding
.tRNA binding
.mitochondrial matrix
.mitochondrion
16 EBI-10172290,EBI-8058160 WNT11  
  .negative regulation of fibroblast growth factor production
.negative regulation of canonical Wnt signaling pathway
.positive regulation of protein kinase C signaling
  + 37 more...
.transcription regulatory region DNA binding
.protein kinase activator activity
.frizzled binding
.GTPase activator activity
.cytoplasm
.extracellular space
.proteinaceous extracellular matrix
.extracellular region
17 EBI-10172290,EBI-719843 HBZ  
  .erythrocyte maturation
.negative regulation of transcription from RNA polymerase II promoter
.heme binding
.oxygen binding
.iron ion binding
.oxygen transporter activity
.extracellular exosome
.hemoglobin complex
18 EBI-10172290,EBI-351935 LMNA  
  .negative regulation of extrinsic apoptotic signaling pathway
.regulation of protein localization to nucleus
.positive regulation of cell aging
  + 17 more...
.structural molecule activity .perinuclear region of cytoplasm
.nuclear membrane
.nuclear speck
  + 8 more...
19 EBI-10172290,EBI-9008836 CHRNG  
  .transmembrane transport
.regulation of membrane potential
.synaptic transmission
  + 3 more...
.acetylcholine receptor activity
.channel activity
.acetylcholine-activated cation-selective channel activity
.postsynaptic membrane
.cell junction
.acetylcholine-gated channel complex
  + 2 more...
20 EBI-10172290,EBI-353467 GSTP1  
  .negative regulation of extrinsic apoptotic signaling pathway
.glutathione derivative biosynthetic process
.negative regulation of monocyte chemotactic protein-1 production
  + 27 more...
.nitric oxide binding
.dinitrosyl-iron complex binding
.S-nitrosoglutathione binding
  + 3 more...
.TRAF2-GSTP1 complex
.extracellular exosome
.vesicle
  + 7 more...
21 EBI-10172290,EBI-3919694 PVR  
  .susceptibility to T cell mediated cytotoxicity
.regulation of immune response
.positive regulation of natural killer cell mediated cytotoxicity
  + 7 more...
.cell adhesion molecule binding
.receptor activity
.extracellular exosome
.integral component of membrane
.cell surface
  + 4 more...
22 EBI-10172290,EBI-10177272 ZNF250  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
23 EBI-10172290,EBI-717634 ZNF20  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
24 EBI-10172290,EBI-2841331 ZNF26  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
25 EBI-10172290,EBI-1965483 ZNF32  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
26 EBI-10172290,EBI-487243 PFKL  
  .canonical glycolysis
.protein homotetramerization
.protein oligomerization
  + 9 more...
.fructose-6-phosphate binding
.fructose binding
.metal ion binding
  + 4 more...
.extracellular exosome
.membrane
.6-phosphofructokinase complex
.cytosol
27 EBI-10172290,EBI-739696 LMO2  
  .cellular response to thyroid hormone stimulus
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of erythrocyte differentiation
  + 3 more...
.E-box binding
.cofactor binding
.bHLH transcription factor binding
  + 7 more...
.transcription factor complex
.nucleus
28 EBI-10172290,EBI-3958099 KRTAP5-9  
  .epidermis development .N/A .keratin filament
29 EBI-10172290,EBI-747133 COL8A1  
  .epithelial cell proliferation
.camera-type eye morphogenesis
.endodermal cell differentiation
  + 6 more...
.N/A .extracellular exosome
.intracellular membrane-bounded organelle
.endoplasmic reticulum lumen
  + 2 more...
30 EBI-10172290,EBI-747754 GRN  
  .positive regulation of epithelial cell proliferation
.embryo implantation
.signal transduction
.blastocyst hatching
.poly(A) RNA binding
.growth factor activity
.extracellular exosome
.intracellular membrane-bounded organelle
.mitochondrion
.extracellular space
31 EBI-10172290,EBI-745213 AQP1  
  .cation transmembrane transport
.maintenance of symbiont-containing vacuole by host
.ammonium transmembrane transport
  + 60 more...
.carbon dioxide transmembrane transporter activity
.nitric oxide transmembrane transporter activity
.transmembrane transporter activity
  + 8 more...
.extracellular exosome
.apical part of cell
.axon terminus
  + 12 more...
32 EBI-10172290,EBI-742094 KRT20  
  .regulation of protein secretion
.intermediate filament organization
.cellular response to stress
.apoptotic process
.structural constituent of cytoskeleton .intermediate filament
.cytoplasm
33 EBI-10172290,EBI-749311 HPCAL1  
  .signal transduction .calcium ion binding .extracellular exosome
34 EBI-10172290,EBI-948821 PTGDS  
  .response to glucocorticoid
.regulation of circadian sleep/wake cycle, sleep
.small molecule metabolic process
  + 4 more...
.fatty acid binding
.retinoid binding
.transporter activity
.prostaglandin-D synthase activity
.extracellular exosome
.perinuclear region of cytoplasm
.nuclear membrane
  + 5 more...
35 EBI-10172290,EBI-3904603 BUD31  
  .regulation of transcription from RNA polymerase II promoter
.mRNA splicing, via spliceosome
.sequence-specific DNA binding transcription factor activity .spliceosomal complex
.nucleus
36 EBI-10172290,EBI-747693 NAA10  
  .N-terminal peptidyl-glutamic acid acetylation
.N-terminal peptidyl-serine acetylation
.internal protein amino acid acetylation
  + 2 more...
.peptide-glutamate-N-acetyltransferase activity
.peptide-serine-N-acetyltransferase activity
.N-acetyltransferase activity
.NatA complex
.cytosolic ribosome
.membrane
  + 4 more...
37 EBI-10172290,EBI-7466542 GLP1R  
  .regulation of insulin secretion
.small molecule metabolic process
.cAMP-mediated signaling
  + 6 more...
.glucagon receptor activity
.transmembrane signaling receptor activity
.integral component of membrane
.plasma membrane
38 EBI-10172290,EBI-2558314 ALDH3B1  
  .oxidation-reduction process
.aldehyde catabolic process
.cellular response to oxidative stress
  + 3 more...
.aldehyde dehydrogenase [NAD(P)+] activity
.3-chloroallyl aldehyde dehydrogenase activity
.extracellular exosome
.vesicle
.plasma membrane
  + 2 more...
39 EBI-10172290,EBI-10210114 NPBWR2  
  .opioid receptor signaling pathway
.synaptic transmission
.neuropeptide signaling pathway
  + 2 more...
.neuropeptide binding
.neuropeptide receptor activity
.opioid receptor activity
.neuron projection
.integral component of membrane
.integral component of plasma membrane
.plasma membrane
40 EBI-10172290,EBI-473775 CLK1  
  .protein autophosphorylation
.regulation of RNA splicing
.peptidyl-threonine phosphorylation
  + 2 more...
.ATP binding
.non-membrane spanning protein tyrosine kinase activity
.protein serine/threonine/tyrosine kinase activity
.protein serine/threonine kinase activity
.cytoplasm
.nucleus
41 EBI-10172290,EBI-750494 SMCP  
  .sperm motility
.penetration of zona pellucida
.N/A .mitochondrial membrane
.mitochondrion
.cytoplasm
42 EBI-10172290,EBI-10211940 MXI1  
  .cytoplasmic sequestering of transcription factor
.negative regulation of cell proliferation
.transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.transcription corepressor activity
.DNA binding
.cytoplasm
.nucleolus
.nucleus
43 EBI-10172290,EBI-2681830 ZNF41  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
44 EBI-10172290,EBI-3905829 CCNG1  
  .cell division
.negative regulation of apoptotic process
.cell growth
  + 6 more...
.N/A .perinuclear region of cytoplasm
.neuronal cell body
.dendrite
.nucleus
45 EBI-10172290,EBI-2687350 ZNF133  
  .transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
46 EBI-10172290,EBI-744104 GEM  
  .metaphase plate congression
.chromosome organization
.metabolic process
  + 5 more...
.GDP binding
.GTP binding
.GTPase activity
.magnesium ion binding
.mitotic spindle
.spindle midzone
.midbody
  + 2 more...
47 EBI-10172290,EBI-2842077 UCP2  
  .liver regeneration
.cellular response to glucose stimulus
.response to fatty acid
  + 16 more...
.N/A .integral component of membrane
.mitochondrial inner membrane
48 EBI-10172290,EBI-724442 RWDD2B  
  .N/A .N/A .N/A
49 EBI-10172290,EBI-10210845 KRTAP12-1  
  .N/A .N/A .keratin filament
50 EBI-10172290,EBI-10172150 KRTAP10-5  
  .N/A .identical protein binding .keratin filament
51 EBI-10172290,EBI-10171774 KRTAP10-8  
  .N/A .N/A .keratin filament
52 EBI-10172290,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
53 EBI-10172290,EBI-720116 GABARAPL2  
  .negative regulation of proteasomal protein catabolic process
.membrane fusion
.nucleophagy
  + 7 more...
.ATPase binding
.GABA receptor binding
.beta-tubulin binding
  + 2 more...
.cytoplasmic vesicle
.extrinsic component of membrane
.cytosol
  + 7 more...
54 EBI-10172290,EBI-353027 RPS28  
  .cellular protein metabolic process
.ribosomal small subunit biogenesis
.viral transcription
  + 10 more...
.poly(A) RNA binding
.structural constituent of ribosome
.extracellular exosome
.cytosolic small ribosomal subunit
.small ribosomal subunit
  + 2 more...
55 EBI-10172290,EBI-354380 RPL11  
  .cellular protein metabolic process
.ribosomal large subunit biogenesis
.protein localization to nucleus
  + 12 more...
.poly(A) RNA binding
.rRNA binding
.structural constituent of ribosome
.RNA binding
.extracellular exosome
.cytosolic large ribosomal subunit
.membrane
  + 3 more...
56 EBI-10172290,EBI-748380 CSNK1G2  
  .positive regulation of canonical Wnt signaling pathway
.protein autophosphorylation
.small molecule metabolic process
  + 8 more...
.peptide binding
.ATP binding
.protein serine/threonine kinase activity
.magnesium ion binding
.membrane
.cytosol
.nucleus
57 EBI-10172290,EBI-10221390 KRT83  
  .hair cycle
.epidermis development
.aging
.structural molecule activity .keratin filament
.extracellular space
58 EBI-10172290,EBI-10192698 CREB5  
  .adipose tissue development
.positive regulation of transcription, DNA-templated
.fat cell differentiation
.transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.extracellular exosome
.nucleus
59 EBI-10172290,EBI-747421 HHEX  
  .primitive streak formation
.DNA conformation change
.hepatocyte differentiation
  + 34 more...
.repressing transcription factor binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 8 more...
.protein-DNA complex
.cytoplasm
.nucleus
60 EBI-10172290,EBI-10223258 PPARD  
  .apoptotic signaling pathway
.cellular response to hypoxia
.adipose tissue development
  + 46 more...
.linoleic acid binding
.sequence-specific DNA binding
.lipid binding
  + 7 more...
.nucleoplasm
.nucleus
61 EBI-10172290,EBI-3951628 TYRO3  
  .platelet aggregation
.neuron cellular homeostasis
.vagina development
  + 20 more...
.phosphatidylinositol 3-kinase binding
.ATP binding
.receptor signaling protein tyrosine kinase activity
  + 2 more...
.integral component of plasma membrane
.endoplasmic reticulum membrane
.nuclear envelope
.nucleus
62 EBI-10172290,EBI-717810 AES  
  .positive regulation of anoikis
.negative regulation of canonical Wnt signaling pathway
.response to interleukin-1
  + 12 more...
.transcription corepressor activity .nucleus
63 EBI-10172290,EBI-2339219 EHHADH  
  .fatty acid beta-oxidation
.internal protein amino acid acetylation
.coenzyme binding
.enzyme binding
.receptor binding
  + 3 more...
.cytosol
.peroxisome
.mitochondrion
64 EBI-10172290,EBI-2602739 FAM27E3  
  .N/A .N/A .N/A
65 EBI-10172290,EBI-10226133 ZNF543  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
66 EBI-10172290,EBI-10181276 GOLGA8DP  
  .N/A .N/A .Golgi apparatus
67 EBI-10172290,EBI-741210 C19orf57  
  .multicellular organismal development .N/A .N/A
68 EBI-10172290,EBI-10227379 ZNF155  
  .transcription, DNA-templated .metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
69 EBI-10172290,EBI-714158 PIN1  
  .negative regulation of cell motility
.negative regulation of ERK1 and ERK2 cascade
.regulation of pathway-restricted SMAD protein phosphorylation
  + 11 more...
.phosphothreonine binding
.phosphoserine binding
.GTPase activating protein binding
  + 2 more...
.midbody
.nuclear speck
.cytoplasm
  + 2 more...
70 EBI-10172290,EBI-10230628 MOBP  
  .nervous system development .structural constituent of myelin sheath .perinuclear region of cytoplasm
.mitochondrion
71 EBI-10172290,EBI-358049 BYSL  
  .cell proliferation
.female pregnancy
.cell adhesion
  + 2 more...
.poly(A) RNA binding .apical part of cell
.intracellular membrane-bounded organelle
.membrane
  + 3 more...
72 EBI-10172290,EBI-953879 PDIA5  
  .oxidation-reduction process
.cell redox homeostasis
.cellular protein metabolic process
  + 4 more...
.oxidoreductase activity
.protein disulfide isomerase activity
.endoplasmic reticulum membrane
.endoplasmic reticulum lumen
.endoplasmic reticulum
73 EBI-10172290,EBI-7115319 ZNF266  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
74 EBI-10172290,EBI-745934 CBX2  
  .development of primary sexual characteristics
.cellular protein metabolic process
.post-translational protein modification
  + 5 more...
.chromatin binding
.DNA binding
.PRC1 complex
.PcG protein complex
.nucleoplasm
  + 3 more...
75 EBI-10172290,EBI-10234020 ZNF846  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
76 EBI-10172290,EBI-10234472 ZNF169  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
77 EBI-10172290,EBI-10235794 P2RY6  
  .transepithelial chloride transport
.positive regulation of smooth muscle cell migration
.phospholipase C-activating G-protein coupled receptor signaling pathway
.UDP-activated nucleotide receptor activity
.G-protein coupled purinergic nucleotide receptor activity
.G-protein coupled receptor activity
.apical plasma membrane
.basolateral plasma membrane
.integral component of plasma membrane
.plasma membrane
78 EBI-10172290,EBI-710310 TCEA2  
  .positive regulation of transcription from RNA polymerase II promoter
.regulation of DNA-templated transcription, elongation
.DNA-templated transcription, elongation
.zinc ion binding
.DNA binding
.transcription elongation factor complex
.centrosome
.nucleoplasm
79 EBI-10172290,EBI-2555767 ZNF124  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
80 EBI-10172290,EBI-3920053 ZSCAN26  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.nucleic acid binding
.nucleus
81 EBI-10172290,EBI-6426443 KLHL38  
  .N/A .N/A .N/A
82 EBI-10172290,EBI-719941 FAM161A  
  .response to stimulus
.cilium assembly
.visual perception
.N/A .ciliary basal body
.photoreceptor connecting cilium
.centrosome
.cytoplasm
83 EBI-10172290,EBI-10240849 ZNF792  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
84 EBI-10172290,EBI-10243533 -  
  .N/A .N/A .N/A
85 EBI-10172290,EBI-751192 FAM76B  
  .protein deneddylation .NEDD8-specific protease activity .nuclear membrane
.nuclear speck
.cytoplasm
  + 2 more...
86 EBI-10172290,EBI-10245456 LCE3E  
  .keratinization .N/A .N/A
87 EBI-10172290,EBI-8640233 AVPI1  
  .cell cycle
.activation of MAPK activity
.N/A .N/A
88 EBI-10172290,EBI-10245897 LINC00242  
  .N/A .N/A .N/A
89 EBI-10172290,EBI-10245913 LCE1B  
  .keratinization .N/A .N/A
90 EBI-10172290,EBI-10246358 LCE4A  
  .keratinization .N/A .N/A
91 EBI-10172290,EBI-10246607 LCE2A  
  .keratinization .N/A .N/A
92 EBI-10172290,EBI-10247271 FAM74A6  
  .N/A .N/A .N/A
93 EBI-10172290,EBI-10248413 -  
  .N/A .N/A .N/A
94 EBI-10172290,EBI-949753 TENC1  
  .multicellular organismal homeostasis
.intracellular signal transduction
.multicellular organism growth
  + 5 more...
.metal ion binding
.kinase binding
.phosphoprotein phosphatase activity
.focal adhesion
.plasma membrane
95 EBI-10172290,EBI-10250516 ZNF425  
  .negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.cytoplasm
.nucleus
96 EBI-10172290,EBI-10250562 KRTAP5-6  
  .N/A .N/A .keratin filament
97 EBI-10172290,EBI-5458784 RPUSD3  
  .pseudouridine synthesis .poly(A) RNA binding
.pseudouridine synthase activity
.N/A
98 EBI-10172290,EBI-1051531 DHX57  
  .RNA processing .metal ion binding
.poly(A) RNA binding
.ATP binding
.ATP-dependent RNA helicase activity
.mitochondrion
.nucleus
99 EBI-10172290,EBI-8635958 SPATA8  
  .N/A .N/A .N/A
100 EBI-10172290,EBI-8481036 RSPO2  
  .positive regulation of canonical Wnt signaling pathway
.trachea cartilage morphogenesis
.epithelial tube branching involved in lung morphogenesis
  + 6 more...
.heparin binding
.receptor binding
.G-protein coupled receptor binding
.cell surface
.extracellular space
.extracellular region
101 EBI-10172290,EBI-10255185 SLC25A48  
  .transmembrane transport .N/A .integral component of membrane
.mitochondrial inner membrane
102 EBI-10172290,EBI-8465456 C16orf59  
  .N/A .N/A .N/A
103 EBI-10172290,EBI-10257016 ZNF572  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
104 EBI-10172290,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
105 EBI-10172290,EBI-10257651 LIMS2  
  .positive regulation of integrin-mediated signaling pathway
.negative regulation of hepatocyte proliferation
.negative regulation of neural precursor cell proliferation
  + 4 more...
.zinc ion binding .focal adhesion
.plasma membrane
.cytosol
.nucleus
106 EBI-10172290,EBI-10258233 CATIP  
  .cilium organization
.actin filament polymerization
.calmodulin binding .actin cytoskeleton
.plasma membrane
.cytoplasm
.nucleus
107 EBI-10172290,EBI-7233259 ZNF329  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
108 EBI-10172290,EBI-10258951 RTN4RL1  
  .axon regeneration .receptor activity .extracellular exosome
.anchored component of plasma membrane
.membrane raft
  + 2 more...
109 EBI-10172290,EBI-8650724 CARKD  
  .nicotinamide nucleotide metabolic process .ADP-dependent NAD(P)H-hydrate dehydratase activity
.ATP-dependent NAD(P)H-hydrate dehydratase activity
.ATP binding
.mitochondrion
110 EBI-10172290,EBI-5278328 ZNF101  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
111 EBI-10172290,EBI-10265447 RNF175  
  .endoplasmic reticulum unfolded protein response
.ER-associated ubiquitin-dependent protein catabolic process
.protein ubiquitination
.ubiquitin protein ligase activity
.zinc ion binding
.integral component of membrane
.endoplasmic reticulum membrane
.Golgi membrane
112 EBI-10172290,EBI-740814 CCDC185  
  .N/A .N/A .N/A
113 EBI-10172290,EBI-10267553 ZNF433  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
114 EBI-10172290,EBI-954696 TCEANC  
  .regulation of DNA-templated transcription, elongation
.regulation of transcription from RNA polymerase II promoter
.transcription, DNA-templated
.DNA binding .nucleus
115 EBI-10172290,EBI-10220600 IQUB  
  .cilium morphogenesis
.smoothened signaling pathway
.N/A .motile cilium
.acrosomal vesicle
116 EBI-10172290,EBI-747580 ZNF439  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
117 EBI-10172290,EBI-10270752 ZNF555  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
118 EBI-10172290,EBI-10271580 CCDC26  
  .N/A .N/A .N/A
119 EBI-10172290,EBI-740727 ZNF417  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
120 EBI-10172290,EBI-3925505 THAP6  
  .N/A .metal ion binding
.DNA binding
.microtubule cytoskeleton
121 EBI-10172290,EBI-742750 BAHD1  
  .negative regulation of transcription, DNA-templated
.heterochromatin assembly
.transcription, DNA-templated
.chromatin silencing
.chromatin binding
.transcription regulatory region sequence-specific DNA binding
.chromatin silencing complex
.nucleoplasm
.chromatin
122 EBI-10172290,EBI-10273713 ZNF564  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
123 EBI-10172290,EBI-3446851 ZNF418  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
124 EBI-10172290,EBI-8637627 AEN  
  .nucleic acid phosphodiester bond hydrolysis
.intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
.response to ionizing radiation
.exonuclease activity
.nucleic acid binding
.nuclear membrane
.nucleolus
.nucleoplasm
.nucleus
125 EBI-10172290,EBI-7199479 PTPMT1  
  .inositol phosphate dephosphorylation
.glycerophospholipid biosynthetic process
.small molecule metabolic process
  + 4 more...
.phosphatidylglycerophosphatase activity
.protein tyrosine/serine/threonine phosphatase activity
.protein tyrosine phosphatase activity
.phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
.integral component of mitochondrial inner membrane
.mitochondrion
.nucleus
126 EBI-10172290,EBI-488533 ING5  
  .positive regulation of apoptotic signaling pathway
.negative regulation of growth
.positive regulation of transcription, DNA-templated
  + 7 more...
.methylated histone binding
.zinc ion binding
.chromatin binding
.MOZ/MORF histone acetyltransferase complex
.nucleoplasm
.nucleus
127 EBI-10172290,EBI-718419 PVRL2  
  .susceptibility to T cell mediated cytotoxicity
.establishment of mitochondrion localization
.regulation of immune response
  + 22 more...
.cell adhesion molecule binding
.protein homodimerization activity
.identical protein binding
  + 2 more...
.extracellular exosome
.integral component of membrane
.cell surface
  + 4 more...
128 EBI-10172290,EBI-751290 PCSK5  
  .embryonic skeletal system development
.embryonic digestive tract development
.neurotrophin TRK receptor signaling pathway
  + 15 more...
.peptide binding
.peptidase activity
.serine-type endopeptidase activity
.secretory granule
.integral component of membrane
.Golgi lumen
  + 2 more...
129 EBI-10172290,EBI-1380477 INPP5D  
  .leukocyte migration
.T cell receptor signaling pathway
.negative regulation of immune response
  + 22 more...
.phosphatidylinositol trisphosphate phosphatase activity
.inositol-polyphosphate 5-phosphatase activity
.membrane
.cytosol
130 EBI-10172290,EBI-8293590 IGSF8  
  .regulation of cell motility
.cell proliferation
.skeletal muscle tissue development
  + 3 more...
.N/A .extracellular exosome
.synapse
.axon
  + 3 more...
131 EBI-10172290,EBI-2877705 RPL36AL  
  .translation .structural constituent of ribosome .cytosolic large ribosomal subunit
132 EBI-10172290,EBI-395708 ZBTB9  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
133 EBI-10172290,EBI-748111 ZNF707  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
134 EBI-10172290,EBI-722584 C9orf9  
  .N/A .N/A .cytoplasmic microtubule
.acrosomal vesicle
135 EBI-10172290,EBI-1045338 TMA16  
  .N/A .N/A .nucleolus
.nucleus
136 EBI-10172290,EBI-5278764 CDCA7L  
  .positive regulation of cell proliferation
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.N/A .cytoplasm
.nucleolus
.nucleus
137 EBI-10172290,EBI-741158 WDYHV1  
  .cellular protein modification process .protein-N-terminal glutamine amidohydrolase activity .cytosol
.nucleus
138 EBI-10172290,EBI-751267 PDLIM5  
  .regulation of dendritic spine morphogenesis
.regulation of synapse assembly
.actinin binding
.zinc ion binding
.protein kinase C binding
.actin binding
.postsynaptic membrane
.neuron projection
.cell junction
  + 5 more...
139 EBI-10172290,EBI-10288482 ZNF419  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
140 EBI-10172290,EBI-4395587 ZNF625  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
141 EBI-10172290,EBI-744859 ANKRD36BP1  
  .N/A .N/A .N/A
142 EBI-10172290,EBI-10291463 ZNF778  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
143 EBI-10172290,EBI-8293751 GUCD1  
  .N/A .N/A .N/A
144 EBI-10172290,EBI-6427977 ZNF587  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
145 EBI-10172290,EBI-10295404 CTRC  
  .proteolysis .peptidase activity
.serine-type endopeptidase activity
.N/A
146 EBI-10172290,EBI-745276 ZNF670  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
147 EBI-10172290,EBI-10297542 ZNF2  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.zinc ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
148 EBI-10172290,EBI-741574 MXD3  
  .negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.DNA binding .nucleus
149 EBI-10172290,EBI-748391 SCNM1  
  .RNA splicing
.mRNA processing
.metal ion binding
.enzyme binding
.nuclear speck
.nucleolus
.nucleus
150 EBI-10172290,EBI-541426 AP1M1  
  .membrane organization
.regulation of defense response to virus by virus
.endosome to melanosome transport
  + 5 more...
.N/A .extracellular exosome
.trans-Golgi network membrane
.clathrin-coated endocytic vesicle membrane
  + 6 more...
151 EBI-10172290,EBI-1044640 KRTAP9-2  
  .N/A .N/A .keratin filament
152 EBI-10172290,EBI-10172511 KRTAP4-2  
  .N/A .N/A .keratin filament
153 EBI-10172290,EBI-7962814 DERL2  
  .retrograde protein transport, ER to cytosol
.endoplasmic reticulum unfolded protein response
.ER-associated ubiquitin-dependent protein catabolic process
  + 3 more...
.N/A .integral component of endoplasmic reticulum membrane
.membrane
.endoplasmic reticulum membrane
  + 3 more...
154 EBI-10172290,EBI-3464833 GABARAPL1  
  .membrane fusion
.nucleophagy
.mitochondrion degradation
.autophagic vacuole assembly
.GABA receptor binding
.beta-tubulin binding
.Tat protein binding
.microtubule binding
.cell body
.dendrite cytoplasm
.dendrite membrane
  + 10 more...
155 EBI-10172290,EBI-748452 PCED1A  
  .N/A .N/A .N/A
156 EBI-10172290,EBI-3918847 HSD3B7  
  .small molecule metabolic process
.bile acid metabolic process
.bile acid biosynthetic process
.cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity
.3-beta-hydroxy-delta5-steroid dehydrogenase activity
.integral component of membrane
.endoplasmic reticulum membrane
157 EBI-10172290,EBI-947551 CHRD  
  .positive regulation of cell adhesion
.negative regulation of osteoblast differentiation
.floor plate development
  + 9 more...
.cytokine binding
.heparin binding
.extracellular space
158 EBI-10172290,EBI-741626 FAM124B  
  .N/A .N/A .N/A
159 EBI-10172290,EBI-715389 C8orf33  
  .N/A .N/A .N/A
160 EBI-10172290,EBI-9996007 RPF1  
  .maturation of LSU-rRNA
.maturation of 5.8S rRNA
.ribosomal large subunit assembly
.poly(A) RNA binding
.rRNA primary transcript binding
.RNA binding
.preribosome, large subunit precursor
.nucleolus
161 EBI-10172290,EBI-633400 CLK4  
  .protein autophosphorylation
.regulation of RNA splicing
.ATP binding
.protein tyrosine kinase activity
.protein serine/threonine/tyrosine kinase activity
.protein serine/threonine kinase activity
.nucleus
162 EBI-10172290,EBI-10310808 TMEM8A  
  .cell adhesion .N/A .extracellular exosome
.integral component of plasma membrane
.plasma membrane
.lysosomal membrane
163 EBI-10172290,EBI-1383814 CSNK1G1  
  .peptidyl-serine phosphorylation
.Wnt signaling pathway
.regulation of cell shape
.endocytosis
.ATP binding
.protein serine/threonine kinase activity
.cytoplasm
.nucleus
164 EBI-10172290,EBI-10311198 SLC6A20  
  .transmembrane transport
.proline transport
.glycine transport
  + 3 more...
.amino acid transmembrane transporter activity
.neurotransmitter:sodium symporter activity
.apical plasma membrane
.integral component of plasma membrane
.plasma membrane
165 EBI-10172290,EBI-9679045 DMRT3  
  .male sex differentiation
.regulation of odontogenesis of dentin-containing tooth
.ventral spinal cord interneuron specification
  + 4 more...
.protein heterodimerization activity
.metal ion binding
.protein homodimerization activity
  + 2 more...
.nucleus
166 EBI-10172290,EBI-2826725 PVRL3  
  .retina morphogenesis in camera-type eye
.cell-cell junction organization
.adherens junction organization
  + 5 more...
.cell adhesion molecule binding
.protein homodimerization activity
.postsynaptic membrane
.apical junction complex
.integral component of membrane
  + 2 more...
167 EBI-10172290,EBI-748927 NPDC1  
  .N/A .N/A .integral component of membrane
168 EBI-10172290,EBI-8640191 SMCO4  
  .N/A .N/A .integral component of membrane
169 EBI-10172290,EBI-747082 CTNNBIP1  
  .negative regulation of mesenchymal cell proliferation
.negative regulation of transcription initiation from RNA polymerase II promoter
.negative regulation of smooth muscle cell proliferation
  + 10 more...
.armadillo repeat domain binding
.beta-catenin binding
.beta-catenin destruction complex
.cytosol
.cytoplasm
  + 2 more...
170 EBI-10172290,EBI-10313481 TREX1  
  .nucleic acid phosphodiester bond hydrolysis
.innate immune response
.positive regulation of type I interferon production
  + 6 more...
.metal ion binding
.protein homodimerization activity
.MutSalpha complex binding
  + 5 more...
.cytosol
.endoplasmic reticulum membrane
.nucleolus
  + 2 more...
171 EBI-10172290,EBI-10313866 C19orf66  
  .N/A .N/A .N/A
172 EBI-10172290,EBI-399076 MRGBP  
  .regulation of growth
.chromatin modification
.regulation of transcription, DNA-templated
  + 2 more...
.N/A .H4/H2A histone acetyltransferase complex
.nucleoplasm
.nucleus
173 EBI-10172290,EBI-741515 THAP1  
  .regulation of mitotic cell cycle
.cell cycle
.regulation of transcription, DNA-templated
  + 2 more...
.sequence-specific DNA binding
.identical protein binding
.zinc ion binding
.PML body
.nucleus
174 EBI-10172290,EBI-740924 PRR13  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.N/A .nucleus
175 EBI-10172290,EBI-745520 ZNF581  
  .transcription from RNA polymerase II promoter
.regulation of transcription from RNA polymerase II promoter
.metal ion binding
.RNA polymerase II regulatory region sequence-specific DNA binding
.nucleus
176 EBI-10172290,EBI-357355 UXT  
  .centrosome organization
.mitochondrion transport along microtubule
.microtubule cytoskeleton organization
.negative regulation of transcription from RNA polymerase II promoter
.beta-tubulin binding
.microtubule binding
.chromatin binding
.RNA polymerase II transcription corepressor activity
.cytoskeleton
.centrosome
.cytoplasm
.nucleus
177 EBI-10172290,EBI-10319970 B4GALT7  
  .negative regulation of fibroblast proliferation
.small molecule metabolic process
.extracellular fibril organization
  + 7 more...
.xylosylprotein 4-beta-galactosyltransferase activity
.manganese ion binding
.galactosyltransferase activity
.beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity
.Golgi cisterna membrane
.integral component of membrane
.Golgi apparatus
.Golgi membrane
178 EBI-10172290,EBI-723716 VTI1B  
  .regulation of protein localization to plasma membrane
.membrane fusion
.vesicle fusion with Golgi apparatus
  + 8 more...
.chloride channel inhibitor activity
.SNAP receptor activity
.SNARE binding
.recycling endosome
.perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
  + 11 more...
179 EBI-10172290,EBI-713677 CRCT1  
  .N/A .N/A .N/A
180 EBI-10172290,EBI-10320765 POLL  
  .somatic hypermutation of immunoglobulin genes
.nucleotide-excision repair
.DNA replication
.metal ion binding
.lyase activity
.DNA-directed DNA polymerase activity
.DNA binding
.nucleus
181 EBI-10172290,EBI-716098 NOL12  
  .N/A .poly(A) RNA binding
.rRNA binding
.nucleolus
182 EBI-10172290,EBI-1759386 SLC23A1  
  .transepithelial L-ascorbic acid transport
.dehydroascorbic acid transport
.small molecule metabolic process
  + 12 more...
.sodium-dependent L-ascorbate transmembrane transporter activity
.dehydroascorbic acid transporter activity
.L-ascorbic acid transporter activity
  + 3 more...
.extracellular exosome
.intracellular organelle
.apical plasma membrane
  + 6 more...
183 EBI-10172290,EBI-10322527 ZNF180  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
184 EBI-10172290,EBI-10322867 ZNF223  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
185 EBI-10172290,EBI-741528 CHIC2  
  .Golgi to plasma membrane transport .N/A .plasma membrane
.Golgi-associated vesicle
186 EBI-10172290,EBI-1105370 ZNF490  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
187 EBI-10172290,EBI-717201 SPG7  
  .anterograde axon cargo transport
.nervous system development
.mitochondrion organization
.proteolysis
.unfolded protein binding
.zinc ion binding
.peptidase activity
  + 2 more...
.mitochondrial membrane
.integral component of membrane
.mitochondrion
188 EBI-10172290,EBI-4291090 GNE  
  .carbohydrate phosphorylation
.cellular protein metabolic process
.post-translational protein modification
  + 6 more...
.metal ion binding
.N-acylmannosamine kinase activity
.UDP-N-acetylglucosamine 2-epimerase activity
  + 2 more...
.cytosol
.cytoplasm
189 EBI-10172290,EBI-2212028 SSX2IP  
  .regulation of cell motility
.centrosome organization
.cilium assembly
  + 3 more...
.N/A .protein complex
.ciliary basal body
.centriolar satellite
  + 3 more...
190 EBI-10172290,EBI-718719 CARHSP1  
  .regulation of mRNA stability
.intracellular signal transduction
.regulation of transcription, DNA-templated
.phosphatase binding
.mRNA 3'-UTR binding
.DNA binding
.extracellular exosome
.P granule
.cytosol
.cytoplasmic mRNA processing body
191 EBI-10172290,EBI-714987 ZNF337  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
192 EBI-10172290,EBI-3438881 ZNF175  
  .defense response to virus
.regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.intermediate filament cytoskeleton
.cytoplasm
.nucleoplasm
193 EBI-10172290,EBI-1048886 NUBP2  
  .small molecule metabolic process
.iron-sulfur cluster assembly
.4 iron, 4 sulfur cluster binding
.metal ion binding
.ATP binding
.nucleotide binding
.spindle pole centrosome
.cytoplasm
.nucleus


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