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> Protein (NX_P60410)
Protein (NX_P60410)
Protein
Gene SymbolKRTAP10-8 to neXtProt (NX_P60410)
DescriptionKeratin-associated protein 10-8
Chromosome21
Location21q22.3 (46031996 ~ 46032871) to Ensembl
Sequene Features : Isoforms 1, Variants 51, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.N/A .N/A .keratin filament
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 51 0
2014-09-19protein level
1 44 0
2014-05-27transcript level
1 44 0
2014-02-25transcript level
1 44 0
2013-12-09transcript level
1 37 0
2013-11-01transcript level
1 36 0
2013-09-12transcript level
1 36 0
2013-08-17transcript level
1 36 0
2013-07-15transcript level
1 29 0
2013-06-11transcript level
1 29 0
2013-02-12transcript level
1 16 0
2012-12-20transcript level
1 16 0
2012-10-30transcript level
1 16 0
2012-10-07transcript level
1 16 0
2012-08-24transcript level
1 15 0
2012-07-28transcript level
1 15 0
2012-06-08transcript level
1 15 0
2012-05-07transcript level
1 14 0
2012-04-10transcript level
1 14 0
2012-01-13transcript level
1 8 0
2011-12-20transcript level
1 8 0
2011-11-11transcript level
1 8 0
2011-08-23transcript level
1 8 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P60410-1
6 0 0 26278.3887
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-10171774,EBI-10171756 SLC22A23  
  .ion transport .transmembrane transporter activity .integral component of membrane
2 EBI-10171774,EBI-6262458 MATN3  
  .extracellular matrix organization
.skeletal system development
.extracellular matrix structural constituent .proteinaceous extracellular matrix
.extracellular region
3 EBI-10171774,EBI-744471 ZBTB24  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.hematopoietic progenitor cell differentiation
.metal ion binding
.DNA binding
.nucleus
4 EBI-10171774,EBI-742487 SPRY2  
  .positive regulation of protein serine/threonine kinase activity
.positive regulation of ERK1 and ERK2 cascade
.negative regulation of ERK1 and ERK2 cascade
  + 19 more...
.protein serine/threonine kinase activator activity
.protein serine/threonine kinase inhibitor activity
.protein kinase binding
.ruffle membrane
.microtubule cytoskeleton
.plasma membrane
  + 2 more...
5 EBI-10171774,EBI-8646694 DCX  
  .dendrite morphogenesis
.axon extension
.protein autophosphorylation
  + 8 more...
.protein kinase binding
.calcium-dependent protein serine/threonine kinase activity
.microtubule binding
  + 2 more...
.neuron projection
.microtubule associated complex
.microtubule
  + 4 more...
6 EBI-10171774,EBI-3866665 SPRY1  
  .negative regulation of ERK1 and ERK2 cascade
.bud elongation involved in lung branching
.negative regulation of neurotrophin TRK receptor signaling pathway
  + 10 more...
.N/A .plasma membrane
.cytosol
7 EBI-10171774,EBI-1053424 PRKAB2  
  .membrane organization
.regulation of protein kinase activity
.small molecule metabolic process
  + 13 more...
.identical protein binding .AMP-activated protein kinase complex
.cytosol
.nucleoplasm
8 EBI-10171774,EBI-947402 MAPKBP1  
  .N/A .N/A .N/A
9 EBI-10171774,EBI-398610 EIF4E2  
  .cytokine-mediated signaling pathway
.negative regulation of translation
.in utero embryonic development
.poly(A) RNA binding
.ubiquitin protein ligase binding
.translation factor activity, RNA binding
  + 2 more...
.mRNA cap binding complex
.cytosol
10 EBI-10171774,EBI-718707 LRCH4  
  .nervous system development .N/A .PML body
11 EBI-10171774,EBI-749295 STK16  
  .cellular response to transforming growth factor beta stimulus
.protein autophosphorylation
.regulation of signal transduction
.ATP binding
.non-membrane spanning protein tyrosine kinase activity
.protein serine/threonine kinase activity
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.perinuclear region of cytoplasm
.membrane
.Golgi-associated vesicle
.cytoplasm
12 EBI-10171774,EBI-374781 GLRX3  
  .cell redox homeostasis
.negative regulation of cardiac muscle hypertrophy
.regulation of the force of heart contraction
.iron-sulfur cluster binding
.metal ion binding
.poly(A) RNA binding
  + 2 more...
.extracellular exosome
.Z disc
.cell cortex
13 EBI-10171774,EBI-742764 PDE9A  
  .cGMP-mediated signaling
.metabolic process
.blood coagulation
.signal transduction
.3',5'-cyclic-GMP phosphodiesterase activity
.metal ion binding
.3',5'-cyclic-nucleotide phosphodiesterase activity
.perinuclear region of cytoplasm
.perikaryon
.ruffle membrane
  + 3 more...
14 EBI-10171774,EBI-353997 GNAI2  
  .regulation of calcium ion transport
.cell division
.negative regulation of synaptic transmission
  + 17 more...
.metal ion binding
.G-protein beta/gamma-subunit complex binding
.GTP binding
  + 3 more...
.extracellular exosome
.membrane raft
.vesicle
  + 8 more...
15 EBI-10171774,EBI-9008836 CHRNG  
  .transmembrane transport
.regulation of membrane potential
.synaptic transmission
  + 3 more...
.acetylcholine receptor activity
.channel activity
.acetylcholine-activated cation-selective channel activity
.postsynaptic membrane
.cell junction
.acetylcholine-gated channel complex
  + 2 more...
16 EBI-10171774,EBI-1052631 ALPI  
  .dephosphorylation .zinc ion binding
.alkaline phosphatase activity
.protease binding
.magnesium ion binding
.anchored component of membrane
.integral component of membrane
.plasma membrane
17 EBI-10171774,EBI-352528 HSPD1  
  .protein maturation
.chaperone-mediated protein complex assembly
.positive regulation of T cell activation
  + 21 more...
.chaperone binding
.unfolded protein binding
.poly(A) RNA binding
  + 8 more...
.extracellular exosome
.lipopolysaccharide receptor complex
.protein complex
  + 13 more...
18 EBI-10171774,EBI-3919694 PVR  
  .susceptibility to T cell mediated cytotoxicity
.regulation of immune response
.positive regulation of natural killer cell mediated cytotoxicity
  + 7 more...
.cell adhesion molecule binding
.receptor activity
.extracellular exosome
.integral component of membrane
.cell surface
  + 4 more...
19 EBI-10171774,EBI-4397076 FAH  
  .small molecule metabolic process
.cellular nitrogen compound metabolic process
.tyrosine catabolic process
  + 2 more...
.metal ion binding
.fumarylacetoacetase activity
.extracellular exosome
.cytosol
20 EBI-10171774,EBI-717634 ZNF20  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
21 EBI-10171774,EBI-1965483 ZNF32  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
22 EBI-10171774,EBI-2320534 WT1  
  .positive regulation of metanephric ureteric bud development
.negative regulation of female gonad development
.positive regulation of male gonad development
  + 44 more...
.C2H2 zinc finger domain binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 4 more...
.nuclear speck
.cytoplasm
.nucleolus
  + 2 more...
23 EBI-10171774,EBI-351257 DDX6  
  .exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay
.cytoplasmic mRNA processing body assembly
.viral RNA genome packaging
  + 4 more...
.poly(A) RNA binding
.protein domain specific binding
.ATP binding
  + 3 more...
.intracellular membrane-bounded organelle
.RISC complex
.membrane
  + 5 more...
24 EBI-10171774,EBI-3958099 KRTAP5-9  
  .epidermis development .N/A .keratin filament
25 EBI-10171774,EBI-747133 COL8A1  
  .epithelial cell proliferation
.camera-type eye morphogenesis
.endodermal cell differentiation
  + 6 more...
.N/A .extracellular exosome
.intracellular membrane-bounded organelle
.endoplasmic reticulum lumen
  + 2 more...
26 EBI-10171774,EBI-740446 OTX1  
  .diencephalon morphogenesis
.positive regulation of transcription from RNA polymerase II promoter
.inner ear morphogenesis
  + 3 more...
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II core promoter proximal region sequence-specific DNA binding
.nucleus
27 EBI-10171774,EBI-742094 KRT20  
  .regulation of protein secretion
.intermediate filament organization
.cellular response to stress
.apoptotic process
.structural constituent of cytoskeleton .intermediate filament
.cytoplasm
28 EBI-10171774,EBI-749311 HPCAL1  
  .signal transduction .calcium ion binding .extracellular exosome
29 EBI-10171774,EBI-7466542 GLP1R  
  .regulation of insulin secretion
.small molecule metabolic process
.cAMP-mediated signaling
  + 6 more...
.glucagon receptor activity
.transmembrane signaling receptor activity
.integral component of membrane
.plasma membrane
30 EBI-10171774,EBI-2558314 ALDH3B1  
  .oxidation-reduction process
.aldehyde catabolic process
.cellular response to oxidative stress
  + 3 more...
.aldehyde dehydrogenase [NAD(P)+] activity
.3-chloroallyl aldehyde dehydrogenase activity
.extracellular exosome
.vesicle
.plasma membrane
  + 2 more...
31 EBI-10171774,EBI-740785 HOXA1  
  .cochlea morphogenesis
.cochlea development
.cellular response to retinoic acid
  + 24 more...
.sequence-specific DNA binding .nucleus
32 EBI-10171774,EBI-750494 SMCP  
  .sperm motility
.penetration of zona pellucida
.N/A .mitochondrial membrane
.mitochondrion
.cytoplasm
33 EBI-10171774,EBI-10211940 MXI1  
  .cytoplasmic sequestering of transcription factor
.negative regulation of cell proliferation
.transcription, DNA-templated
.negative regulation of transcription from RNA polymerase II promoter
.transcription corepressor activity
.DNA binding
.cytoplasm
.nucleolus
.nucleus
34 EBI-10171774,EBI-10213071 ZNF138  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.sequence-specific DNA binding transcription factor activity
.DNA binding
.nucleus
35 EBI-10171774,EBI-10210845 KRTAP12-1  
  .N/A .N/A .keratin filament
36 EBI-10171774,EBI-10176379 KRTAP12-2  
  .N/A .N/A .keratin filament
37 EBI-10171774,EBI-10172290 KRTAP10-7  
  .N/A .identical protein binding .keratin filament
38 EBI-10171774,EBI-10172052 KRTAP10-9  
  .N/A .N/A .keratin filament
39 EBI-10171774,EBI-353027 RPS28  
  .cellular protein metabolic process
.ribosomal small subunit biogenesis
.viral transcription
  + 10 more...
.poly(A) RNA binding
.structural constituent of ribosome
.extracellular exosome
.cytosolic small ribosomal subunit
.small ribosomal subunit
  + 2 more...
40 EBI-10171774,EBI-10221390 KRT83  
  .hair cycle
.epidermis development
.aging
.structural molecule activity .keratin filament
.extracellular space
41 EBI-10171774,EBI-10221726 ADAMTSL3  
  .N/A .zinc ion binding
.metallopeptidase activity
.proteinaceous extracellular matrix
42 EBI-10171774,EBI-10192698 CREB5  
  .adipose tissue development
.positive regulation of transcription, DNA-templated
.fat cell differentiation
.transcription from RNA polymerase II promoter
.metal ion binding
.sequence-specific DNA binding
.sequence-specific DNA binding transcription factor activity
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.extracellular exosome
.nucleus
43 EBI-10171774,EBI-747421 HHEX  
  .primitive streak formation
.DNA conformation change
.hepatocyte differentiation
  + 34 more...
.repressing transcription factor binding
.transcription regulatory region DNA binding
.sequence-specific DNA binding
  + 8 more...
.protein-DNA complex
.cytoplasm
.nucleus
44 EBI-10171774,EBI-10223946 WT1-AS  
  .N/A .N/A .N/A
45 EBI-10171774,EBI-3951628 TYRO3  
  .platelet aggregation
.neuron cellular homeostasis
.vagina development
  + 20 more...
.phosphatidylinositol 3-kinase binding
.ATP binding
.receptor signaling protein tyrosine kinase activity
  + 2 more...
.integral component of plasma membrane
.endoplasmic reticulum membrane
.nuclear envelope
.nucleus
46 EBI-10171774,EBI-717810 AES  
  .positive regulation of anoikis
.negative regulation of canonical Wnt signaling pathway
.response to interleukin-1
  + 12 more...
.transcription corepressor activity .nucleus
47 EBI-10171774,EBI-2602739 FAM27E3  
  .N/A .N/A .N/A
48 EBI-10171774,EBI-10181276 GOLGA8DP  
  .N/A .N/A .Golgi apparatus
49 EBI-10171774,EBI-714236 MTA1  
  .negative regulation of nucleic acid-templated transcription
.positive regulation of protein autoubiquitination
.regulation of inflammatory response
  + 11 more...
.zinc ion binding
.transcription corepressor activity
.transcription coactivator activity
  + 5 more...
.intracellular membrane-bounded organelle
.NuRD complex
.microtubule
  + 4 more...
50 EBI-10171774,EBI-7813714 PKD2  
  .negative regulation of G1/S transition of mitotic cell cycle
.regulation of calcium ion import
.metanephric S-shaped body morphogenesis
  + 45 more...
.phosphoprotein binding
.ATPase binding
.calcium-induced calcium release activity
  + 13 more...
.mitotic spindle
.integral component of lumenal side of endoplasmic reticulum membrane
.integral component of cytoplasmic side of endoplasmic reticulum membrane
  + 16 more...
51 EBI-10171774,EBI-2510602 JOSD1  
  .N/A .omega peptidase activity .membrane
.plasma membrane
.cytoplasm
52 EBI-10171774,EBI-8641936 NAB2  
  .regulation of epidermis development
.myelination
.negative regulation of transcription from RNA polymerase III promoter
  + 5 more...
.transcription corepressor activity .nucleus
53 EBI-10171774,EBI-2555767 ZNF124  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
54 EBI-10171774,EBI-6426443 KLHL38  
  .N/A .N/A .N/A
55 EBI-10171774,EBI-10243533 -  
  .N/A .N/A .N/A
56 EBI-10171774,EBI-751192 FAM76B  
  .protein deneddylation .NEDD8-specific protease activity .nuclear membrane
.nuclear speck
.cytoplasm
  + 2 more...
57 EBI-10171774,EBI-10245291 LCE3C  
  .keratinization .N/A .N/A
58 EBI-10171774,EBI-10245456 LCE3E  
  .keratinization .N/A .N/A
59 EBI-10171774,EBI-10245913 LCE1B  
  .keratinization .N/A .N/A
60 EBI-10171774,EBI-10246358 LCE4A  
  .keratinization .N/A .N/A
61 EBI-10171774,EBI-10246607 LCE2A  
  .keratinization .N/A .N/A
62 EBI-10171774,EBI-10246750 LCE2D  
  .keratinization .N/A .N/A
63 EBI-10171774,EBI-10247271 FAM74A6  
  .N/A .N/A .N/A
64 EBI-10171774,EBI-10248413 -  
  .N/A .N/A .N/A
65 EBI-10171774,EBI-949753 TENC1  
  .multicellular organismal homeostasis
.intracellular signal transduction
.multicellular organism growth
  + 5 more...
.metal ion binding
.kinase binding
.phosphoprotein phosphatase activity
.focal adhesion
.plasma membrane
66 EBI-10171774,EBI-715463 GLYAT  
  .small molecule metabolic process
.monocarboxylic acid metabolic process
.response to toxic substance
  + 3 more...
.glycine N-benzoyltransferase activity
.glycine N-acyltransferase activity
.transferase activity, transferring acyl groups
.extracellular exosome
.mitochondrial matrix
.mitochondrion
67 EBI-10171774,EBI-10250562 KRTAP5-6  
  .N/A .N/A .keratin filament
68 EBI-10171774,EBI-6660291 C11orf87  
  .N/A .N/A .integral component of membrane
69 EBI-10171774,EBI-1051531 DHX57  
  .RNA processing .metal ion binding
.poly(A) RNA binding
.ATP binding
.ATP-dependent RNA helicase activity
.mitochondrion
.nucleus
70 EBI-10171774,EBI-10173507 ADAMTSL4  
  .cellular protein metabolic process
.post-translational protein modification
.positive regulation of apoptotic process
  + 4 more...
.metalloendopeptidase activity
.protease binding
.endoplasmic reticulum lumen
.interstitial matrix
71 EBI-10171774,EBI-727146 ATG9A  
  .innate immune response
.late nucleophagy
.piecemeal microautophagy of nucleus
  + 5 more...
.N/A .recycling endosome
.late endosome membrane
.cytoplasmic vesicle
  + 8 more...
72 EBI-10171774,EBI-10257016 ZNF572  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
73 EBI-10171774,EBI-945833 NOTCH2NL  
  .cell differentiation
.multicellular organismal development
.Notch signaling pathway
.calcium ion binding .cytoplasm
.extracellular region
74 EBI-10171774,EBI-2799342 TMEM150A  
  .regulation of autophagy
.catabolic process
.N/A .integral component of membrane
.plasma membrane
.lysosome
75 EBI-10171774,EBI-10258951 RTN4RL1  
  .axon regeneration .receptor activity .extracellular exosome
.anchored component of plasma membrane
.membrane raft
  + 2 more...
76 EBI-10171774,EBI-8650724 CARKD  
  .nicotinamide nucleotide metabolic process .ADP-dependent NAD(P)H-hydrate dehydratase activity
.ATP-dependent NAD(P)H-hydrate dehydratase activity
.ATP binding
.mitochondrion
77 EBI-10171774,EBI-747580 ZNF439  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
78 EBI-10171774,EBI-741032 CNNM3  
  .ion transport .N/A .integral component of membrane
.membrane
.plasma membrane
79 EBI-10171774,EBI-744545 CATSPER1  
  .membrane depolarization during action potential
.calcium ion import
.regulation of cilium beat frequency involved in ciliary motility
  + 9 more...
.voltage-gated calcium channel activity
.calcium activated cation channel activity
.CatSper complex
.motile cilium
.plasma membrane
80 EBI-10171774,EBI-5459844 DDX55  
  .RNA secondary structure unwinding .poly(A) RNA binding
.ATP binding
.ATP-dependent RNA helicase activity
.membrane
.cytoplasm
.nucleolus
81 EBI-10171774,EBI-10271580 CCDC26  
  .N/A .N/A .N/A
82 EBI-10171774,EBI-742060 TYMSOS  
  .N/A .N/A .N/A
83 EBI-10171774,EBI-740727 ZNF417  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
84 EBI-10171774,EBI-8637627 AEN  
  .nucleic acid phosphodiester bond hydrolysis
.intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
.response to ionizing radiation
.exonuclease activity
.nucleic acid binding
.nuclear membrane
.nucleolus
.nucleoplasm
.nucleus
85 EBI-10171774,EBI-751409 ZNF473  
  .mRNA 3'-end processing
.gene expression
.histone mRNA metabolic process
  + 4 more...
.metal ion binding
.DNA binding
.Cajal body
.nucleoplasm
86 EBI-10171774,EBI-7199479 PTPMT1  
  .inositol phosphate dephosphorylation
.glycerophospholipid biosynthetic process
.small molecule metabolic process
  + 4 more...
.phosphatidylglycerophosphatase activity
.protein tyrosine/serine/threonine phosphatase activity
.protein tyrosine phosphatase activity
.phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
.integral component of mitochondrial inner membrane
.mitochondrion
.nucleus
87 EBI-10171774,EBI-2866213 KIAA0247  
  .cell death
.cellular response to DNA damage stimulus
.N/A .integral component of membrane
88 EBI-10171774,EBI-448771 DOCK2  
  .positive regulation of phagocytosis
.regulation of defense response to virus by virus
.alpha-beta T cell proliferation
  + 12 more...
.T cell receptor binding
.Rac guanyl-nucleotide exchange factor activity
.extracellular exosome
.membrane
.endomembrane system
  + 2 more...
89 EBI-10171774,EBI-751290 PCSK5  
  .embryonic skeletal system development
.embryonic digestive tract development
.neurotrophin TRK receptor signaling pathway
  + 15 more...
.peptide binding
.peptidase activity
.serine-type endopeptidase activity
.secretory granule
.integral component of membrane
.Golgi lumen
  + 2 more...
90 EBI-10171774,EBI-8293590 IGSF8  
  .regulation of cell motility
.cell proliferation
.skeletal muscle tissue development
  + 3 more...
.N/A .extracellular exosome
.synapse
.axon
  + 3 more...
91 EBI-10171774,EBI-741068 FBXW5  
  .centrosome duplication
.proteasome-mediated ubiquitin-dependent protein catabolic process
.SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
  + 2 more...
.protein kinase binding .Cul4-RING E3 ubiquitin ligase complex
.SCF ubiquitin ligase complex
.cytoplasm
92 EBI-10171774,EBI-722584 C9orf9  
  .N/A .N/A .cytoplasmic microtubule
.acrosomal vesicle
93 EBI-10171774,EBI-2509913 TNIP3  
  .cellular response to lipopolysaccharide
.negative regulation of I-kappaB kinase/NF-kappaB signaling
.toll-like receptor 4 signaling pathway
  + 2 more...
.polyubiquitin binding .N/A
94 EBI-10171774,EBI-746300 DHRS1  
  .N/A .oxidoreductase activity .endoplasmic reticulum
.mitochondrial inner membrane
95 EBI-10171774,EBI-2908273 PIGS  
  .cellular protein metabolic process
.post-translational protein modification
.attachment of GPI anchor to protein
.C-terminal protein lipidation
.GPI-anchor transamidase activity .GPI-anchor transamidase complex
.membrane
.endoplasmic reticulum membrane
96 EBI-10171774,EBI-6427977 ZNF587  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.metal ion binding
.DNA binding
.nucleus
97 EBI-10171774,EBI-3916225 FOXB1  
  .cell migration in diencephalon
.inferior colliculus development
.mammary gland lobule development
  + 19 more...
.sequence-specific DNA binding
.sequence-specific DNA binding RNA polymerase II transcription factor activity
.nucleus
98 EBI-10171774,EBI-2849569 ZFYVE21  
  .N/A .metal ion binding .cytoplasmic membrane-bounded vesicle
.focal adhesion
.endosome
99 EBI-10171774,EBI-739863 KRTAP4-12  
  .N/A .N/A .keratin filament
100 EBI-10171774,EBI-5457544 UTP23  
  .maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) .small ribosomal subunit rRNA binding
.poly(A) RNA binding
.small-subunit processome
.nucleolus
101 EBI-10171774,EBI-741350 THAP7  
  .negative regulation of transcription, DNA-templated
.transcription, DNA-templated
.C2H2 zinc finger domain binding
.protein N-terminus binding
.metal ion binding
.DNA binding
.nuclear speck
.chromosome
102 EBI-10171774,EBI-748391 SCNM1  
  .RNA splicing
.mRNA processing
.metal ion binding
.enzyme binding
.nuclear speck
.nucleolus
.nucleus
103 EBI-10171774,EBI-745073 BEX2  
  .regulation of cell cycle
.regulation of apoptotic process
.cell cycle
.apoptotic process
.N/A .cytoplasm
.nucleus
104 EBI-10171774,EBI-10185730 KRTAP9-4  
  .N/A .N/A .keratin filament
105 EBI-10171774,EBI-1044640 KRTAP9-2  
  .N/A .N/A .keratin filament
106 EBI-10171774,EBI-10302392 KRTAP4-11  
  .N/A .N/A .keratin filament
107 EBI-10171774,EBI-10302547 KRTAP4-7  
  .hair cycle
.aging
.N/A .keratin filament
108 EBI-10171774,EBI-10172511 KRTAP4-2  
  .N/A .N/A .keratin filament
109 EBI-10171774,EBI-1993677 ASPSCR1  
  .membrane organization
.regulation of glucose import
.glucose homeostasis
.intracellular protein transport
.N/A .perinuclear region of cytoplasm
.intracellular membrane-bounded organelle
.endoplasmic reticulum-Golgi intermediate compartment membrane
  + 7 more...
110 EBI-10171774,EBI-743787 YIPF3  
  .cell differentiation .N/A .intracellular membrane-bounded organelle
.transport vesicle
.integral component of membrane
  + 3 more...
111 EBI-10171774,EBI-7962814 DERL2  
  .retrograde protein transport, ER to cytosol
.endoplasmic reticulum unfolded protein response
.ER-associated ubiquitin-dependent protein catabolic process
  + 3 more...
.N/A .integral component of endoplasmic reticulum membrane
.membrane
.endoplasmic reticulum membrane
  + 3 more...
112 EBI-10171774,EBI-748452 PCED1A  
  .N/A .N/A .N/A
113 EBI-10171774,EBI-373380 VPS11  
  .positive regulation of protein targeting to mitochondrion
.vesicle-mediated transport
.intracellular protein transport
.syntaxin binding
.zinc ion binding
.nucleotide binding
.late endosome membrane
.HOPS complex
.endocytic vesicle
  + 4 more...
114 EBI-10171774,EBI-3918847 HSD3B7  
  .small molecule metabolic process
.bile acid metabolic process
.bile acid biosynthetic process
.cholest-5-ene-3-beta,7-alpha-diol 3-beta-dehydrogenase activity
.3-beta-hydroxy-delta5-steroid dehydrogenase activity
.integral component of membrane
.endoplasmic reticulum membrane
115 EBI-10171774,EBI-947551 CHRD  
  .positive regulation of cell adhesion
.negative regulation of osteoblast differentiation
.floor plate development
  + 9 more...
.cytokine binding
.heparin binding
.extracellular space
116 EBI-10171774,EBI-2801103 SMOC1  
  .limb development
.regulation of osteoblast differentiation
.extracellular matrix organization
  + 4 more...
.extracellular matrix binding
.calcium ion binding
.basement membrane
117 EBI-10171774,EBI-633400 CLK4  
  .protein autophosphorylation
.regulation of RNA splicing
.ATP binding
.protein tyrosine kinase activity
.protein serine/threonine/tyrosine kinase activity
.protein serine/threonine kinase activity
.nucleus
118 EBI-10171774,EBI-1267176 PTPRH  
  .peptidyl-tyrosine dephosphorylation
.apoptotic process
.protein dephosphorylation
.transmembrane receptor protein tyrosine phosphatase activity .integral component of plasma membrane
.cytoplasm
119 EBI-10171774,EBI-10311198 SLC6A20  
  .transmembrane transport
.proline transport
.glycine transport
  + 3 more...
.amino acid transmembrane transporter activity
.neurotransmitter:sodium symporter activity
.apical plasma membrane
.integral component of plasma membrane
.plasma membrane
120 EBI-10171774,EBI-9679045 DMRT3  
  .male sex differentiation
.regulation of odontogenesis of dentin-containing tooth
.ventral spinal cord interneuron specification
  + 4 more...
.protein heterodimerization activity
.metal ion binding
.protein homodimerization activity
  + 2 more...
.nucleus
121 EBI-10171774,EBI-2826725 PVRL3  
  .retina morphogenesis in camera-type eye
.cell-cell junction organization
.adherens junction organization
  + 5 more...
.cell adhesion molecule binding
.protein homodimerization activity
.postsynaptic membrane
.apical junction complex
.integral component of membrane
  + 2 more...
122 EBI-10171774,EBI-10313866 C19orf66  
  .N/A .N/A .N/A
123 EBI-10171774,EBI-2853126 TBC1D23  
  .regulation of inflammatory response
.positive regulation of interleukin-6 production
.regulation of tumor necrosis factor production
.N/A .N/A
124 EBI-10171774,EBI-8799578 GFOD1  
  .N/A .oxidoreductase activity .extracellular region
125 EBI-10171774,EBI-740924 PRR13  
  .regulation of transcription, DNA-templated
.transcription, DNA-templated
.N/A .nucleus
126 EBI-10171774,EBI-10198848 LUZP4  
  .N/A .N/A .nucleus
127 EBI-10171774,EBI-745404 THAP10  
  .N/A .metal ion binding
.DNA binding
.N/A
128 EBI-10171774,EBI-357355 UXT  
  .centrosome organization
.mitochondrion transport along microtubule
.microtubule cytoskeleton organization
.negative regulation of transcription from RNA polymerase II promoter
.beta-tubulin binding
.microtubule binding
.chromatin binding
.RNA polymerase II transcription corepressor activity
.cytoskeleton
.centrosome
.cytoplasm
.nucleus
129 EBI-10171774,EBI-750394 SLC25A10  
  .sulfide oxidation, using sulfide:quinone oxidoreductase
.transmembrane transport
.small molecule metabolic process
  + 9 more...
.dicarboxylic acid transmembrane transporter activity .integral component of membrane
.mitochondrial inner membrane
.nucleus
130 EBI-10171774,EBI-713677 CRCT1  
  .N/A .N/A .N/A
131 EBI-10171774,EBI-1759386 SLC23A1  
  .transepithelial L-ascorbic acid transport
.dehydroascorbic acid transport
.small molecule metabolic process
  + 12 more...
.sodium-dependent L-ascorbate transmembrane transporter activity
.dehydroascorbic acid transporter activity
.L-ascorbic acid transporter activity
  + 3 more...
.extracellular exosome
.intracellular organelle
.apical plasma membrane
  + 6 more...
132 EBI-10171774,EBI-741528 CHIC2  
  .Golgi to plasma membrane transport .N/A .plasma membrane
.Golgi-associated vesicle
133 EBI-10171774,EBI-4291090 GNE  
  .carbohydrate phosphorylation
.cellular protein metabolic process
.post-translational protein modification
  + 6 more...
.metal ion binding
.N-acylmannosamine kinase activity
.UDP-N-acetylglucosamine 2-epimerase activity
  + 2 more...
.cytosol
.cytoplasm
134 EBI-10171774,EBI-10326419 R3HDM2  
  .N/A .poly(A) RNA binding .nucleus
135 EBI-10171774,EBI-718719 CARHSP1  
  .regulation of mRNA stability
.intracellular signal transduction
.regulation of transcription, DNA-templated
.phosphatase binding
.mRNA 3'-UTR binding
.DNA binding
.extracellular exosome
.P granule
.cytosol
.cytoplasmic mRNA processing body
136 EBI-10171774,EBI-10281938 ZSCAN21  
  .positive regulation of transcription from RNA polymerase II promoter
.regulation of transcription, DNA-templated
.metal ion binding
.RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
.RNA polymerase II core promoter proximal region sequence-specific DNA binding
.nucleus
137 EBI-10171774,EBI-3922719 WIF1  
  .negative regulation of canonical Wnt signaling pathway
.positive regulation of fat cell differentiation
.Wnt signaling pathway
  + 2 more...
.N/A .extracellular region
138 EBI-10171774,EBI-10329546 LYVE1  
  .small molecule metabolic process
.hyaluronan catabolic process
.hyaluronan metabolic process
  + 7 more...
.hyaluronic acid binding
.transmembrane signaling receptor activity
.receptor activity
.extracellular exosome
.membrane
.integral component of plasma membrane
.plasma membrane


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