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> Protein (NX_P61009)
Protein (NX_P61009)
Protein
Gene SymbolSPCS3 to neXtProt (NX_P61009)
DescriptionSignal peptidase complex subunit 3
Chromosome4
Location4q34.2 (177241115 ~ 177253396) to Ensembl
Sequene Features : Isoforms 1, Variants 13, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.regulation of insulin secretion
.cellular protein metabolic process
.gene expression
  + 3 more...
.peptidase activity .integral component of membrane
.endoplasmic reticulum membrane
.signal peptidase complex
.endoplasmic reticulum
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 13 4
2014-09-19protein level
1 9 4
2014-05-27protein level
1 9 4
2014-02-25protein level
1 9 4
2013-12-09protein level
1 8 4
2013-11-01protein level
1 8 3
2013-09-12protein level
1 8 3
2013-08-17protein level
1 8 3
2013-07-15protein level
1 6 1
2013-06-11protein level
1 6 1
2013-02-12protein level
1 2 1
2012-12-20protein level
1 2 1
2012-10-30protein level
1 2 1
2012-10-07protein level
1 2 1
2012-08-24protein level
1 2 1
2012-07-28protein level
1 2 1
2012-06-08protein level
1 3 1
2012-05-07protein level
1 3 1
2012-04-10protein level
1 3 1
2012-01-13protein level
1 3 1
2011-12-20protein level
1 3 1
2011-11-11protein level
1 3 1
2011-08-23protein level
1 3 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P61009-1
7 0 0 20300.4808
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
ascites75
blood65
bone41
bone marrow20
brain29
cervix20
connective tissue33
embryonic tissue51
eye33
heart33
intestine77
kidney66
larynx42
liver14
lung26
lymph45
lymph node77
mammary gland33
mouth105
muscle28
ovary19
pancreas79
pharynx73
placenta109
prostate47
skin52
stomach52
testis55
thymus37
thyroid64
trachea154
umbilical cord145
uterus51
vascular77
Health State
TissuesTPM*
normal55
breast (mammary gland) tumor10
cervical tumor28
chondrosarcoma36
colorectal tumor97
gastrointestinal tumor59
germ cell tumor26
glioma9
head and neck tumor74
kidney tumor72
leukemia21
liver tumor10
lung tumor9
lymphoma27
non-neoplasia31
ovarian tumor26
pancreatic tumor9
prostate cancer38
retinoblastoma43
skin tumor47
uterine tumor77
Developmental Stage
TissuesTPM*
adult51
embryoid body42
blastocyst65
neonate96
fetus50
infant42
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue30.2
adrenal gland27.8
appendix59.6
bone marrow60.3
cerebral cortex31.8
colon40.4
duodenum35.7
esophagus28.9
gallbladder38.1
heart muscle30.6
kidney31.7
liver23.9
lung39.3
lymph node55.3
ovary23.8
pancreas33.2
placenta44.2
prostate36.2
salivary gland76.8
skin25.7
small intestine39.3
spleen49
stomach52.8
testis14.7
thyroid gland70
urinary bladder50.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected


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