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> Protein (NX_P61026)
Protein (NX_P61026)
Protein
Gene SymbolRAB10 to neXtProt (NX_P61026)
DescriptionRas-related protein Rab-10
Chromosome2
Location2p23.3 (26256976 ~ 26360323) to Ensembl
Sequene Features : Isoforms 1, Variants 18, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.establishment of protein localization to endoplasmic reticulum membrane
.establishment of protein localization to membrane
.protein localization to plasma membrane
  + 18 more...
.myosin V binding
.GDP binding
.GTP binding
.GTPase activity
.primary cilium
.endoplasmic reticulum tubular network
.extracellular exosome
  + 11 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 18 4
2014-09-19protein level
1 11 4
2014-05-27protein level
1 11 4
2014-02-25protein level
1 10 4
2013-12-09protein level
1 9 4
2013-11-01protein level
1 8 3
2013-09-12protein level
1 8 3
2013-08-17protein level
1 8 3
2013-07-15protein level
1 5 3
2013-06-11protein level
1 5 3
2013-02-12protein level
1 2 3
2012-12-20protein level
1 2 3
2012-10-30protein level
1 3 3
2012-10-07protein level
1 3 3
2012-08-24protein level
1 3 3
2012-07-28protein level
1 3 3
2012-06-08protein level
1 4 3
2012-05-07protein level
1 3 3
2012-04-10protein level
1 3 3
2012-01-13protein level
1 2 3
2011-12-20protein level
1 2 3
2011-11-11protein level
1 2 3
2011-08-23protein level
1 2 3
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P61026-1
6 0 2 22526.5248
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-726075,EBI-748974 OPTN  
  .Golgi ribbon formation
.defense response to Gram-negative bacterium
.negative regulation of I-kappaB kinase/NF-kappaB signaling
  + 10 more...
.K63-linked polyubiquitin binding
.identical protein binding
.polyubiquitin binding
  + 2 more...
.recycling endosome
.perinuclear region of cytoplasm
.cytoplasmic membrane-bounded vesicle
  + 8 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue155
adrenal gland151
ascites75
bladder133
blood57
bone139
bone marrow430
brain233
cervix226
connective tissue127
ear186
embryonic tissue183
esophagus198
eye119
heart44
intestine176
kidney75
larynx85
liver141
lung119
lymph112
lymph node590
mammary gland257
mouth393
muscle197
ovary19
pancreas112
parathyroid339
pharynx73
pituitary gland121
placenta144
prostate131
skin128
spleen112
stomach104
testis241
thymus112
thyroid171
trachea753
uterus245
vascular251
Health State
TissuesTPM*
normal158
adrenal tumor316
bladder carcinoma113
breast (mammary gland) tumor64
cervical tumor86
chondrosarcoma144
colorectal tumor133
esophageal tumor231
gastrointestinal tumor67
germ cell tumor265
glioma205
head and neck tumor246
kidney tumor87
leukemia476
liver tumor208
lung tumor107
lymphoma83
non-neoplasia134
ovarian tumor52
pancreatic tumor161
primitive neuroectodermal tumor of the CNS165
prostate cancer173
retinoblastoma43
skin tumor119
soft tissue/muscle tissue tumor175
uterine tumor199
Developmental Stage
TissuesTPM*
adult155
embryoid body242
blastocyst146
neonate128
fetus161
infant42
juvenile179
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue59.8
adrenal gland72
appendix74.5
bone marrow22.8
cerebral cortex75.2
colon95.8
duodenum55.9
esophagus375.1
gallbladder81.9
heart muscle61.4
kidney67.4
liver42.8
lung49.4
lymph node66.2
ovary52
pancreas33.2
placenta66.3
prostate54.1
salivary gland49.7
skin83.1
small intestine61.5
spleen57
stomach92.4
testis44.4
thyroid gland98.8
urinary bladder123.8
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612672, gene) Ras-associated protein rab10; RAB10OMIM


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