Home| Contact Us

HOME SEARCH STATISTICS
> Protein (NX_P61966)
Protein (NX_P61966)
Protein
Gene SymbolAP1S1 to neXtProt (NX_P61966)
DescriptionAP-1 complex subunit sigma-1A
Chromosome7
Location7q22.1 (100797678 ~ 100804877) to Ensembl
Sequene Features : Isoforms 2, Variants 16, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.membrane organization
.regulation of defense response to virus by virus
.antigen processing and presentation of exogenous peptide antigen via MHC class II
  + 5 more...
.protein transporter activity .extracellular exosome
.trans-Golgi network membrane
.clathrin-coated endocytic vesicle membrane
  + 7 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 16 3
2014-09-19protein level
2 11 3
2014-05-27protein level
2 11 3
2014-02-25protein level
2 11 3
2013-12-09protein level
2 10 3
2013-11-01protein level
2 10 3
2013-09-12protein level
2 10 3
2013-08-17protein level
2 10 3
2013-07-15protein level
2 4 1
2013-06-11protein level
2 4 1
2013-02-12protein level
2 1 1
2012-12-20protein level
2 1 1
2012-10-30protein level
2 1 1
2012-10-07protein level
2 1 1
2012-08-24protein level
2 1 1
2012-07-28protein level
2 1 1
2012-06-08protein level
2 0 1
2012-05-07protein level
2 0 1
2012-04-10protein level
2 0 1
2012-01-13protein level
2 0 1
2011-12-20protein level
2 0 1
2011-11-11protein level
2 0 1
2011-08-23protein level
2 0 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P61966-1
3 3 2 18720.5511
NX_P61966-2
1 3 2 16000.1114
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
ascites150
blood24
bone83
brain33
cervix82
connective tissue6
embryonic tissue79
eye43
intestine56
kidney28
liver38
lung74
lymph22
lymph node22
mammary gland105
muscle28
nerve128
ovary68
pancreas23
placenta60
prostate31
skin66
stomach41
testis36
uterus12
Health State
TissuesTPM*
normal26
adrenal tumor79
breast (mammary gland) tumor150
cervical tumor57
chondrosarcoma72
colorectal tumor62
gastrointestinal tumor67
germ cell tumor79
glioma93
kidney tumor72
leukemia21
liver tumor62
lung tumor97
lymphoma55
non-neoplasia10
ovarian tumor91
pancreatic tumor19
primitive neuroectodermal tumor of the CNS70
prostate cancer48
retinoblastoma21
skin tumor55
soft tissue/muscle tissue tumor23
uterine tumor11
Developmental Stage
TissuesTPM*
adult41
embryoid body57
blastocyst32
fetus28
juvenile71
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue19.8
adrenal gland24.6
appendix20.6
bone marrow6.8
cerebral cortex94.1
colon53.8
duodenum48.1
esophagus25.6
gallbladder32.6
heart muscle11.5
kidney47
liver28.8
lung20.4
lymph node21.9
ovary21.6
pancreas12.9
placenta31.5
prostate31
salivary gland23
skin28.7
small intestine44.3
spleen19.9
stomach36.9
testis22
thyroid gland36.8
urinary bladder42.2
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowLow
breastMedium
bronchusMedium
cerebellumMedium
cerebral cortexMedium
cervix, uterineLow
colonMedium
duodenumMedium
endometrium 1Medium
endometrium 2Medium
esophagusLow
fallopian tubeMedium
gallbladderMedium
hippocampusLow
kidneyMedium
liverMedium
lungLow
lymph nodeLow
oral mucosaMedium
ovaryLow
pancreasMedium
parathyroid glandLow
placentaLow
prostateMedium
rectumMedium
salivary glandMedium
skin 2Low
small intestineMedium
spleenLow
stomach 1Medium
stomach 2Medium
testisMedium
thyroid glandLow
tonsilMedium
urinary bladderMedium
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603531, gene) Adaptor-related protein complex 1, sigma-1 subunit; AP1S1OMIM
2(%609313, phenotype) Erythrokeratodermia variabilis 3OMIM


#424, YPRC/BPRC, Industry-University Research Center, Yonsei Univ., Seodaemun-gu, Seoul, Korea, 120-749
Tel: +82-2-2123-6626, Fax: +82-2-393-6589
2014-2019 (C) Yonsei Proteome Research Center