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> Protein (NX_P62068)
Protein (NX_P62068)
Protein
Gene SymbolUSP46 to neXtProt (NX_P62068)
DescriptionUbiquitin carboxyl-terminal hydrolase 46
Chromosome4
Location4q12 (53457138 ~ 53525502) to Ensembl
Sequene Features : Isoforms 4, Variants 35, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.righting reflex
.behavioral response to ethanol
.regulation of synaptic transmission, GABAergic
  + 4 more...
.ubiquitin-specific protease activity .N/A
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
4 35 0
2014-09-19protein level
4 28 0
2014-05-27protein level
4 28 0
2014-02-25protein level
4 28 0
2013-12-09protein level
4 28 0
2013-11-01protein level
4 28 0
2013-09-12protein level
4 28 0
2013-08-17protein level
4 28 0
2013-07-15protein level
4 14 0
2013-06-11protein level
4 14 0
2013-02-12protein level
4 3 0
2012-12-20protein level
4 4 0
2012-10-30protein level
4 4 0
2012-10-07protein level
4 4 0
2012-08-24protein level
4 2 0
2012-07-28protein level
4 2 0
2012-06-08protein level
4 5 0
2012-05-07protein level
4 5 0
2012-04-10protein level
4 5 0
2012-01-13protein level
4 5 0
2011-12-20protein level
4 5 0
2011-11-11protein level
4 4 0
2011-08-23protein level
4 4 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P62068-1
0 11 6 42415.0051
NX_P62068-2
2 6 4 26225.9846
NX_P62068-3
1 10 6 41704.5965
NX_P62068-4
1 10 6 41085.4603
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
bladder33
bone27
brain111
cervix41
connective tissue26
embryonic tissue61
eye14
heart11
kidney23
liver9
lung32
lymph node22
mammary gland46
mouth45
muscle37
ovary9
parathyroid97
pharynx24
placenta67
prostate15
skin18
spleen18
stomach104
testis71
thymus25
thyroid42
trachea77
uterus38
vascular58
Health State
TissuesTPM*
normal66
breast (mammary gland) tumor10
cervical tumor57
chondrosarcoma36
gastrointestinal tumor84
germ cell tumor64
glioma93
head and neck tumor29
kidney tumor14
liver tumor10
lung tumor19
non-neoplasia41
ovarian tumor13
primitive neuroectodermal tumor of the CNS7
prostate cancer9
skin tumor7
soft tissue/muscle tissue tumor39
uterine tumor33
Developmental Stage
TissuesTPM*
adult44
embryoid body42
blastocyst65
fetus86
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue4.5
adrenal gland10.8
appendix4.6
bone marrow2.3
cerebral cortex32.2
colon5.3
duodenum4.7
esophagus15.3
gallbladder8.2
heart muscle28
kidney10.8
liver1.7
lung4.8
lymph node4.5
ovary12.4
pancreas3.7
placenta7.3
prostate8.1
salivary gland7.2
skin7.2
small intestine5.1
spleen3.8
stomach6.7
testis15.9
thyroid gland12.1
urinary bladder11.1
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*612849, gene) Ubiquitin-specific peptidase 46; USP46OMIM


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