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> Protein (NX_P62330)
Protein (NX_P62330)
Protein
Gene SymbolARF6 to neXtProt (NX_P62330)
DescriptionADP-ribosylation factor 6
Chromosome14
Location14q21.3 (50359810 ~ 50361490) to Ensembl
Sequene Features : Isoforms 1, Variants 9, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.hepatocyte apoptotic process
.establishment of epithelial cell polarity
.positive regulation of establishment of protein localization to plasma membrane
  + 19 more...
.thioesterase binding
.GTP binding
.GTPase activity
.extracellular exosome
.recycling endosome membrane
.cleavage furrow
  + 11 more...
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 9 3
2014-09-19protein level
1 8 3
2014-05-27protein level
1 8 3
2014-02-25protein level
1 8 3
2013-12-09protein level
1 8 3
2013-11-01protein level
1 8 1
2013-09-12protein level
1 8 1
2013-08-17protein level
1 8 1
2013-07-15protein level
1 6 1
2013-06-11protein level
1 6 1
2013-02-12protein level
1 2 1
2012-12-20protein level
1 2 1
2012-10-30protein level
1 2 1
2012-10-07protein level
1 2 1
2012-08-24protein level
1 2 1
2012-07-28protein level
1 2 1
2012-06-08protein level
1 5 1
2012-05-07protein level
1 4 1
2012-04-10protein level
1 4 1
2012-01-13protein level
1 17 1
2011-12-20protein level
1 17 1
2011-11-11protein level
1 17 1
2011-08-23protein level
1 17 1
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P62330-1
7 0 0 20069.377
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-638181,EBI-1023301 SPAG9  
  .negative regulation of protein homodimerization activity
.protein homooligomerization
.positive regulation of muscle cell differentiation
  + 7 more...
.receptor signaling complex scaffold activity
.kinesin binding
.JUN kinase binding
.MAP-kinase scaffold activity
.extracellular exosome
.perinuclear region of cytoplasm
.integral component of membrane
  + 3 more...
2 EBI-638181,EBI-988663 ATP6V1C1  
  .phagosome maturation
.transmembrane transport
.interaction with host
  + 6 more...
.proton-transporting ATPase activity, rotational mechanism
.hydrogen-exporting ATPase activity, phosphorylative mechanism
.transporter activity
.extracellular exosome
.apical part of cell
.proton-transporting V-type ATPase, V1 domain
  + 5 more...
3 EBI-638181,EBI-638194 ARFIP2  
  .regulation of Arp2/3 complex-mediated actin nucleation
.ruffle organization
.actin cytoskeleton organization
  + 3 more...
.phosphatidylinositol-4-phosphate binding
.Rac GTPase binding
.GTP-dependent protein binding
.GTP binding
.trans-Golgi network membrane
.cell cortex
.plasma membrane
  + 2 more...
4 EBI-638181,EBI-306852 KIF23  
  .mitotic spindle midzone assembly
.positive regulation of cytokinesis
.antigen processing and presentation of exogenous peptide antigen via MHC class II
  + 7 more...
.ATPase activity
.microtubule binding
.ATP binding
.microtubule motor activity
.centralspindlin complex
.mitotic spindle
.intercellular bridge
  + 9 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland60
ascites225
bladder200
blood73
bone83
bone marrow20
connective tissue13
ear62
eye4
heart11
liver4
lung8
lymph node44
mammary gland6
muscle9
pancreas4
placenta3
skin4
stomach10
testis4
uterus12
Health State
TissuesTPM*
normal68
bladder carcinoma113
breast (mammary gland) tumor225
cervical tumor57
chondrosarcoma84
colorectal tumor337
gastrointestinal tumor135
germ cell tumor140
glioma65
head and neck tumor321
kidney tumor43
leukemia31
liver tumor62
lung tumor48
lymphoma83
non-neoplasia72
ovarian tumor65
pancreatic tumor47
primitive neuroectodermal tumor of the CNS102
prostate cancer125
skin tumor151
soft tissue/muscle tissue tumor95
uterine tumor188
Developmental Stage
TissuesTPM*
adult117
embryoid body71
blastocyst32
neonate64
fetus35
infant42
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue34.2
adrenal gland22.1
appendix44.6
bone marrow99.9
cerebral cortex13.6
colon57.9
duodenum40.4
esophagus101.5
gallbladder39.8
heart muscle16
kidney31.2
liver33.4
lung39.3
lymph node59.2
ovary17.2
pancreas14.9
placenta40.5
prostate32.1
salivary gland30.5
skin41.7
small intestine48.4
spleen55.9
stomach55.3
testis24.9
thyroid gland22.2
urinary bladder45.6
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*600464, gene) Adp-ribosylation factor 6; ARF6OMIM


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