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> Protein (NX_P62508)
Protein (NX_P62508)
Protein
Gene SymbolESRRG to neXtProt (NX_P62508)
DescriptionEstrogen-related receptor gamma
Chromosome1
Location1q41 (216676588 ~ 217311097) to Ensembl
Sequene Features : Isoforms 5, Variants 117, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of transcription, DNA-templated
.gene expression
.transcription initiation from RNA polymerase II promoter
.regulation of transcription, DNA-templated
.AF-2 domain binding
.zinc ion binding
.steroid binding
  + 4 more...
.nucleoplasm
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
5 117 2
2014-09-19protein level
5 84 2
2014-05-27protein level
5 84 2
2014-02-25protein level
5 59 2
2013-12-09protein level
5 51 2
2013-11-01protein level
5 51 2
2013-09-12protein level
5 51 2
2013-08-17protein level
5 51 2
2013-07-15protein level
4 50 2
2013-06-11protein level
4 50 2
2013-02-12protein level
3 9 6
2012-12-20protein level
3 10 6
2012-10-30protein level
3 9 6
2012-10-07protein level
3 9 2
2012-08-24protein level
3 2 2
2012-07-28protein level
3 2 2
2012-06-08protein level
3 18 2
2012-05-07protein level
3 18 2
2012-04-10protein level
3 18 2
2012-01-13protein level
3 19 2
2011-12-20protein level
3 19 2
2011-11-11protein level
3 19 2
2011-08-23protein level
3 19 2
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P62508-1
1 14 5 51272.4862
NX_P62508-2
0 14 5 48549.2652
NX_P62508-3
0 15 5 49283.6231
NX_P62508-4
0 14 4 44044.0914
NX_P62508-5
2 15 5 52428.1747
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-2834260,EBI-308778 KIAA1598  
  .regulation of neuron migration
.regulation of establishment of cell polarity
.axon guidance
.N/A .axonal growth cone
2 EBI-2834260,EBI-946109 NR0B1  
  .Sertoli cell differentiation
.negative regulation of transcription, DNA-templated
.negative regulation of cell differentiation
  + 17 more...
.AF-2 domain binding
.sequence-specific DNA binding
.protein homodimerization activity
  + 9 more...
.polysomal ribosome
.membrane
.cytoplasm
  + 2 more...
3 EBI-2834260,EBI-748597 CCDC67  
  .multi-ciliated epithelial cell differentiation
.de novo centriole assembly
.cell projection organization
.N/A .deuterosome
.cytoplasm
4 EBI-2834260,EBI-295715 NUP160  
  .regulation of cellular response to heat
.transmembrane transport
.small molecule metabolic process
  + 18 more...
.nucleocytoplasmic transporter activity .nuclear pore outer ring
.cytosol
.nuclear pore
.nuclear envelope
5 EBI-2834260,EBI-2125614 KIFC3  
  .epithelial cell-cell adhesion
.zonula adherens maintenance
.metabolic process
  + 3 more...
.ATPase activity
.ATP binding
.microtubule motor activity
.extracellular exosome
.cytoplasmic vesicle membrane
.zonula adherens
  + 4 more...
6 EBI-2834260,EBI-765486 PPARGC1A  
  .positive regulation of ATP biosynthetic process
.positive regulation of energy homeostasis
.regulation of N-methyl-D-aspartate selective glutamate receptor activity
  + 51 more...
.androgen receptor binding
.sequence-specific DNA binding
.ubiquitin protein ligase binding
  + 9 more...
.PML body
.cytosol
.DNA-directed RNA polymerase II, core complex
  + 2 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adrenal gland30
brain5
embryonic tissue9
eye67
heart11
intestine4
kidney33
mammary gland6
mouth15
muscle18
placenta84
salivary gland49
testis2
trachea19
uterus4
Health State
TissuesTPM*
normal1
adrenal tumor79
breast (mammary gland) tumor10
germ cell tumor7
head and neck tumor7
kidney tumor14
primitive neuroectodermal tumor of the CNS7
retinoblastoma21
uterine tumor11
Developmental Stage
TissuesTPM*
adult1
fetus3
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adrenal gland7
cerebral cortex4.4
duodenum5.4
esophagus3.6
gallbladder1.2
heart muscle14.1
kidney25.7
pancreas3.4
placenta15.6
prostate4.6
salivary gland15.7
small intestine5.2
spleen1.3
stomach22.7
testis1.3
thyroid gland13.2
urinary bladder1.4
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602969, gene) Estrogen-related receptor, gamma; ESRRGOMIM


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