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> Protein (NX_P63272)
Protein (NX_P63272)
Protein
Gene SymbolSUPT4H1 to neXtProt (NX_P63272)
DescriptionTranscription elongation factor SPT4
Chromosome17
Location17q22 (56422539 ~ 56430454) to Ensembl
Sequene Features : Isoforms 1, Variants 12, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.positive regulation of viral transcription
.positive regulation of transcription from RNA polymerase II promoter
.negative regulation of transcription elongation from RNA polymerase II promoter
  + 10 more...
.protein heterodimerization activity
.zinc ion binding
.sequence-specific DNA binding transcription factor activity
.DSIF complex
.nucleoplasm
.nucleus
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 12 4
2014-09-19protein level
1 9 4
2014-05-27protein level
1 9 4
2014-02-25protein level
1 9 4
2013-12-09protein level
1 8 4
2013-11-01protein level
1 8 3
2013-09-12protein level
1 8 2
2013-08-17protein level
1 8 2
2013-07-15protein level
1 4 1
2013-06-11protein level
1 4 1
2013-02-12protein level
1 3 1
2012-12-20protein level
1 4 1
2012-10-30protein level
1 4 1
2012-10-07protein level
1 4 1
2012-08-24protein level
1 2 1
2012-07-28protein level
1 2 1
2012-06-08protein level
1 3 1
2012-05-07protein level
1 3 1
2012-04-10protein level
1 3 1
2012-01-13protein level
1 1 1
2011-12-20protein level
1 1 1
2011-11-11protein level
1 1 1
2011-08-23protein level
1 1 0
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P63272-1
5 0 0 13184.4689
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-727250,EBI-710464 SUPT5H  
  .negative regulation of mRNA polyadenylation
.positive regulation of viral transcription
.positive regulation of transcription from RNA polymerase II promoter
  + 14 more...
.protein heterodimerization activity
.poly(A) RNA binding
.enzyme binding
.chromatin binding
.DSIF complex
.nucleoplasm
.nucleus
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue233
adrenal gland91
ascites50
blood98
bone marrow20
brain5
connective tissue6
eye23
intestine8
lung2
lymph45
lymph node89
ovary9
pituitary gland60
placenta7
thymus50
tonsil58
vascular19
Health State
TissuesTPM*
normal74
adrenal tumor79
bladder carcinoma56
breast (mammary gland) tumor64
chondrosarcoma181
colorectal tumor26
gastrointestinal tumor50
germ cell tumor26
glioma37
head and neck tumor37
kidney tumor72
leukemia52
liver tumor145
lung tumor77
lymphoma96
non-neoplasia62
ovarian tumor105
pancreatic tumor76
primitive neuroectodermal tumor of the CNS125
prostate cancer48
retinoblastoma172
skin tumor135
soft tissue/muscle tissue tumor63
uterine tumor22
Developmental Stage
TissuesTPM*
adult77
embryoid body114
blastocyst81
fetus91
infant85
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue43.3
adrenal gland57.7
appendix48.9
bone marrow71.7
cerebral cortex38.9
colon46.8
duodenum34.1
esophagus32.6
gallbladder39.6
heart muscle36.3
kidney55
liver35.1
lung41.4
lymph node57.4
ovary42.7
pancreas20.9
placenta42.6
prostate44.6
salivary gland33
skin27.3
small intestine38.1
spleen55.8
stomach43.5
testis32.2
thyroid gland39.5
urinary bladder47.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*603555, gene) Suppressor of ty 4, s. cerevisiae, homolog of, 1; SUPT4H1OMIM


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