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> Protein (NX_P68363)
Protein (NX_P68363)
Protein
Gene SymbolTUBA1B to neXtProt (NX_P68363)
DescriptionTubulin alpha-1B chain
Chromosome12
Location12q13.12 (49521565 ~ 49525180) to Ensembl
Sequene Features : Isoforms 2, Variants 30, PTMsto neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.cellular response to interleukin-4
.cell division
.protein polymerization
  + 6 more...
.ubiquitin protein ligase binding
.GTP binding
.structural constituent of cytoskeleton
  + 3 more...
.extracellular exosome
.cytoplasmic microtubule
.microtubule
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
2 30 9
2014-09-19protein level
2 23 9
2014-05-27protein level
1 23 29
2014-02-25protein level
1 23 29
2013-12-09protein level
1 21 29
2013-11-01protein level
1 21 29
2013-09-12protein level
1 21 31
2013-08-17protein level
1 21 31
2013-07-15protein level
1 13 17
2013-06-11protein level
1 13 17
2013-02-12protein level
1 4 22
2012-12-20protein level
1 4 22
2012-10-30protein level
1 5 22
2012-10-07protein level
1 5 22
2012-08-24protein level
1 3 22
2012-07-28protein level
1 3 22
2012-06-08protein level
1 7 22
2012-05-07protein level
1 7 22
2012-04-10protein level
1 7 22
2012-01-13protein level
1 25 22
2011-12-20protein level
1 25 22
2011-11-11protein level
1 25 17
2011-08-23protein level
1 24 14
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P68363-1
0 0 21 50119.4653
NX_P68363-2
1 0 17 37193.9904
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-487083,EBI-350989 TUBB3  
  .protein polymerization
.'de novo' posttranslational protein folding
.cellular protein metabolic process
  + 4 more...
.peptide binding
.GTP binding
.structural constituent of cytoskeleton
.GTPase activity
.cell periphery
.extracellular exosome
.neuronal cell body
  + 5 more...
2 EBI-487083,EBI-741181 AGTRAP  
  .regulation of blood pressure
.response to hypoxia
.angiotensin type II receptor activity .intracellular membrane-bounded organelle
.cytoplasmic vesicle membrane
.integral component of membrane
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
adipose tissue932
adrenal gland1214
ascites5598
bladder502
blood1603
bone1340
bone marrow1641
brain495
cervix5279
connective tissue1281
ear62
embryonic tissue3123
esophagus1984
eye2791
heart1407
intestine2357
kidney1409
larynx170
liver3000
lung3437
lymph6545
lymph node1013
mammary gland780
mouth120
muscle3008
nerve1480
ovary2335
pancreas1199
parathyroid194
pharynx1424
pituitary gland484
placenta1741
prostate954
salivary gland2615
skin1988
spleen1011
stomach1557
testis1835
thymus1756
thyroid64
tonsil3466
trachea19
umbilical cord1671
uterus2003
vascular600
Health State
TissuesTPM*
normal328
adrenal tumor1343
bladder carcinoma511
breast (mammary gland) tumor870
cervical tumor6669
chondrosarcoma1219
colorectal tumor3030
esophageal tumor1101
gastrointestinal tumor3215
germ cell tumor3787
glioma1501
head and neck tumor470
kidney tumor3688
leukemia1629
liver tumor5217
lung tumor8407
lymphoma4931
non-neoplasia7027
ovarian tumor1745
pancreatic tumor1971
prostate cancer1627
retinoblastoma9625
skin tumor3102
soft tissue/muscle tissue tumor4829
uterine tumor1298
Developmental Stage
TissuesTPM*
embryoid body2243
blastocyst2929
neonate1255
fetus1206
infant39385
juvenile8349
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue352.9
adrenal gland229.5
appendix507.8
bone marrow636.8
cerebral cortex595
colon477.4
duodenum210.3
esophagus364.1
gallbladder269.6
heart muscle253.4
kidney123.2
liver102.7
lung359.5
lymph node533.4
ovary261
pancreas75.2
placenta428.4
prostate166.3
salivary gland147.3
skin281
small intestine259.8
spleen254.6
stomach222.5
testis290.4
thyroid gland186.7
urinary bladder403
Tissues
TissuesExpression level
adrenal glandMedium
appendixMedium
bone marrowMedium
breastMedium
bronchusHigh
cerebellumMedium
cerebral cortexHigh
cervix, uterineMedium
colonHigh
duodenumMedium
endometrium 1Medium
endometrium 2Medium
epididymisHigh
esophagusLow
fallopian tubeHigh
gallbladderMedium
heart muscleLow
hippocampusHigh
kidneyMedium
lateral ventricleHigh
liverLow
lungMedium
lymph nodeHigh
nasopharynxHigh
oral mucosaLow
ovaryLow
pancreasMedium
parathyroid glandMedium
placentaMedium
prostateMedium
rectumHigh
salivary glandLow
seminal vesicleHigh
skeletal muscleLow
skin 1Medium
skin 2Low
small intestineHigh
smooth muscleMedium
soft tissue 1Medium
soft tissue 2Medium
spleenMedium
stomach 1High
stomach 2Medium
testisHigh
thyroid glandHigh
tonsilHigh
urinary bladderHigh
vaginaLow
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Expression level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602530, gene) Tubulin, alpha-1b; TUBA1BOMIM


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