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> Protein (NX_P78357)
Protein (NX_P78357)
Protein
Gene SymbolCNTNAP1 to neXtProt (NX_P78357)
DescriptionContactin-associated protein 1
Chromosome17
Location17q21.2 (40834631 ~ 40851832) to Ensembl
Sequene Features : Isoforms 1, Variants 143, PTMs 28 to neXtProt Sequence Features
Gene
Ontologies
GO: Biological Process GO: Mulecular Function GO: Cellular Component
.neuromuscular process controlling balance
.neuromuscular process controlling posture
.neuron projection morphogenesis
  + 9 more...
.SH3 domain binding
.SH3/SH2 adaptor activity
.receptor activity
.paranode region of axon
.integral component of membrane
.voltage-gated potassium channel complex
.integral component of plasma membrane
Proteomic Evidences
ReleaseProtein EvidencePrAbIsoformsVariantsPTMs
2015-01-01protein level
1 143 28
2014-09-19protein level
1 100 28
2014-05-27protein level
1 100 28
2014-02-25protein level
1 98 28
2013-12-09protein level
1 81 28
2013-11-01protein level
1 72 28
2013-09-12protein level
1 72 29
2013-08-17protein level
1 72 29
2013-07-15protein level
1 53 29
2013-06-11protein level
1 53 29
2013-02-12protein level
1 26 29
2012-12-20protein level
1 28 29
2012-10-30protein level
1 28 29
2012-10-07protein level
1 28 29
2012-08-24protein level
1 26 29
2012-07-28protein level
1 26 29
2012-06-08protein level
1 29 29
2012-05-07protein level
1 15 29
2012-04-10protein level
1 15 29
2012-01-13protein level
1 8 29
2011-12-20protein level
1 8 29
2011-11-11protein level
1 8 29
2011-08-23protein level
1 8 29
Protein Isoforms
Isoform Ac UGSMw (Da)
NX_P78357-1
67 0 0 156166.6797
: Uniquely mapped peptide
: Gene-specific peptide
: Shared peptide
Interacting Partners
No. Exp. ref. Symbol   PE Pr Ab Di   GO: Biological Process GO: Mulecular Function GO: Cellular Component
1 EBI-1751903,EBI-389883 NCK1  
  .negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
.negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
.negative regulation of PERK-mediated unfolded protein response
  + 23 more...
.eukaryotic initiation factor eIF2 binding
.receptor tyrosine kinase binding
.protein binding, bridging
  + 5 more...
.vesicle membrane
.cell-cell junction
.plasma membrane
  + 6 more...
EST expression level of Protein Coding Gene (ref. NCBI UniGene EST)
Body Sites
TissuesTPM*
bone41
brain31
connective tissue20
embryonic tissue28
eye62
heart33
intestine4
larynx255
liver9
lung14
muscle9
nerve128
ovary9
pancreas4
pharynx49
placenta14
prostate10
testis2
uterus12
vascular19
Health State
TissuesTPM*
normal17
chondrosarcoma36
germ cell tumor3
glioma65
head and neck tumor59
liver tumor20
non-neoplasia31
primitive neuroectodermal tumor of the CNS7
retinoblastoma21
soft tissue/muscle tissue tumor7
Developmental Stage
TissuesTPM*
adult20
embryoid body57
blastocyst32
fetus28
juvenile35
TPM*: Transcripts per million; transcript expression level measured by expression sequence tags.
Expression level of Protein (ref. Human Protein Atlas)
RNA-Seq.
TissuesFPKM
adipose tissue5.7
adrenal gland2.5
appendix6.6
cerebral cortex34.3
colon4.3
duodenum1.7
esophagus2.8
gallbladder7.9
heart muscle3.4
kidney1.8
lung5.4
lymph node3.5
ovary9
pancreas3.6
placenta4.7
prostate4.5
salivary gland1.4
skin2.1
small intestine2.5
spleen4
stomach3.4
testis3.5
thyroid gland1.6
urinary bladder7.2
Cancer
TumorNumber of patients and Staining levels
breast cancer
carcinoid
cervical cancer
colorectal cancer
endometrial cancer
glioma
head and neck cancer
liver cancer
lung cancer
lymphoma
melanoma
ovarian cancer
pancreatic cancer
prostate cancer
renal cancer
skin cancer
stomach cancer
testis cancer
thyroid cancer
urothelial cancer
RNA-seq colour codes
Highly expressed RNAs (FPKM >50)
Moderately expressed RNAs (50> FPKM >10)
Lower expressed RNAs (10> FPKM >1)
The lowest expressed RNAs (FPKM value of 0 or 1)
Staining level colour codes
Highly expressed protein
Moderately expressed protein
Lower expressed protein
Not Detected
Disease
No.Disease DescriptionRef.
1(*602346, gene) Contactin-associated protein 1; CNTNAP1OMIM


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